| Ryedale Communications LLP | | 2017 |
| Ryedale Creative Limited | Professional & scientific | 2023 |
| Ryedale Cycling Ltd | Wholesale & retail | 2013 |
| Ryedale Design & Develop Limited | Real estate | 2020 |
| Ryedale Entertainments Limited | Information & communication | 2002 |
| Ryedale Estate Agency Limited | Financial services | 2020 |
| Ryedale Events Limited | Professional & scientific | 2017 |
| Ryedale Food-Aid C.I.C. | Health & social care | 2022 |
| Ryedale Homecare Limited | Health & social care | 2004 |
| Ryedale Paws Ltd | Other services | 2026 |
| Ryedale Plumbers Limited | Construction | 1984 |
| Ryedale Property Services Ltd | Households | 2019 |
| Ryedale Reformer Pilates Limited | Arts & recreation | 2025 |
| Ryedale Safety Management Limited | Professional & scientific | 2023 |
| Ryedale Testing Limited | Construction | 2023 |
| Ryedale Vapour Limited | Wholesale & retail | 2013 |
| Ryedale Vintners Limited | Wholesale & retail | 1982 |
| Ryedale Y.M.C.A. | Hospitality | 1996 |
| Ryetec Industrial Equipment Limited | Manufacturing | 1992 |
| Röckk Limited | Construction | 2025 |
| S & J Contract Services Ltd | Administrative & support | 2018 |
| S Allsop Consulting Limited | Professional & scientific | 2025 |
| S J T Yorkshire Limited | Professional & scientific | 2025 |
| S&B Yorkshire Holdings Ltd | Financial services | 2025 |
| S.J. Apex Limited | Health & social care | 2000 |
| Saffllie Limited | Financial services | 2021 |
| Sally Steadman Ltd | Professional & scientific | 2022 |
| Sallyducks.Com Ltd | Administrative & support | 2023 |
| Saltmer Construction Ltd | Construction | 2020 |
| SAM Garnett Properties Ltd | Real estate | 2025 |
| SAM Lander Porsche Engineering Ltd | Wholesale & retail | 2023 |
| Sanzaru Communications Limited | Professional & scientific | 2010 |
| SBZ Logistics Ltd | Transport & logistics | 2024 |
| Scampston Conservatory Preservation Company Ltd | Administrative & support | 2010 |
| Scampston Farming Company Limited | Agriculture & fishing | 1972 |
| Scoops Ahoy Limited | Hospitality | 2021 |
| Scoops Ingredients Ltd | Wholesale & retail | 2024 |
| Scoradale Limited | Real estate | 1993 |
| Scothern Construction Limited | Construction | 1989 |
| Scothern Developments Limited | Construction | 1995 |
| Scothern Homes (Winterton) Ltd | Construction | 2015 |
| Scotica Holdings Limited | Financial services | 2020 |
| Scotica Limited | Professional & scientific | 2016 |
| Seda Cosmetic Company Limited | Manufacturing | 2014 |
| Seekings & Wardle Financial Services Limited | Financial services | 2004 |
| Selby Piper Limited | Manufacturing | 2014 |
| Selby Piper Technologies Limited | Professional & scientific | 2020 |
| Sentinel Protection Limited | Manufacturing | 2024 |
| Serenity Plumbing and Heating Ltd | Construction | 2025 |
| Shasta Holdings Ltd | Information & communication | 2016 |
| Shipton Estates Limited | Real estate | 1938 |
| Shire Fixings Limited | Wholesale & retail | 2021 |
| Shire Woodlands Ltd | Agriculture & fishing | 2024 |
| Shopper Lens Ltd | Professional & scientific | 2025 |
| Showtime Supplies Ltd | Wholesale & retail | 2023 |
| Simon Boyes Offshore Ltd | Construction | 2020 |
| Simon Naylor Fencing Limited | Construction | 2019 |
| Site Rite SEC Ltd | Administrative & support | 2014 |
| Site Security Services LLP | | 2024 |
| SIX Valley Lamb Ltd | Agriculture & fishing | 2022 |
| SJC Malton Developments Limited | Construction | 2010 |
| SJG Design Ltd | Construction | 2013 |
| SJG Temporary Works Ltd | Construction | 2012 |
| SJG Training Ltd | Education | 2016 |
| SJS Properties (Yorkshire) Limited | Real estate | 2021 |
| Skelton Property Ltd | Real estate | 2025 |
| Sky Scaffolding (Whitby) Limited | Administrative & support | 2002 |
| Skyline Builders Yorkshire Limited | Construction | 2020 |
| SLR Housing Services Ltd | Real estate | 2024 |
| Soak Insure Limited | Financial services | 2022 |
| Sofina Foods Limited | Administrative & support | 2017 |
| Sparkiespares.Com Limited | Wholesale & retail | 2012 |
| Sparky Electrical and Refrigeration Limited | Manufacturing | 2021 |
| Spectrum Solicitors Limited | Professional & scientific | 2015 |
| Spencer Electrical (Yorkshire) Limited | Construction | 2021 |
| Springfield Farms (Sherburn) Limited | Agriculture & fishing | 1957 |
| Springhead Property Limited | Construction | 2021 |
| ST. Quintin Investments Ltd | Real estate | 2016 |
| Stallybrass Associates LLP | | 2011 |
| Star Kebap Limited | Hospitality | 2026 |
| Starchild Nurseries Ltd | Education | 2016 |
| Station Court (Malton) Management Company Limited | Households | 1995 |
| Steel Roofing Ltd | Construction | 2010 |
| Step Forward Renewable (SFR) Ltd | Wholesale & retail | 2023 |
| Stephen Pickering Traditional Building Services Ltd | Construction | 2010 |
| Stirchley Bacon Co. Limited | Wholesale & retail | 1982 |
| Stirchley Bacon Holdings Limited | Financial services | 2006 |
| Stockbroker Ltd | Wholesale & retail | 2023 |
| Stone & Associates Architects Ltd | Professional & scientific | 2011 |
| Stones West Heslerton Limited | Wholesale & retail | 1982 |
| Strand Publishing UK Ltd | Information & communication | 2009 |
| Straws Lifestyle Limited | Wholesale & retail | 2020 |
| Stuart Young Construction Limited | Construction | 2014 |
| Studio K Beauty Ltd | Other services | 2024 |
| Studio Laith Limited | Professional & scientific | 2026 |
| Stuff AS Dreams Limited | Health & social care | 2024 |
| Sulcata Properties Limited | Real estate | 2022 |
| Sundella Limited | Financial services | 2025 |
| Sundyne Technologies Ltd | Information & communication | 2026 |
| Surgitex Limited | Professional & scientific | 2003 |