| Environaid Limited | Wholesale & retail | 2023 |
| Environment First Limited | Water & waste | 2001 |
| Envirotainer Ltd | Transport & logistics | 2011 |
| Envirotainer Services Ltd | Administrative & support | 2000 |
| Envobee Shrimp Ltd | Wholesale & retail | 2018 |
| Envomax Technologies Limited | Extraterritorial | 2012 |
| EON Professional Development Ltd | Information & communication | 2019 |
| EOS Futures Ltd | Wholesale & retail | 2011 |
| EOS Services Ltd | Construction | 2023 |
| EP Aviation Ltd | Manufacturing | 2022 |
| Epic Engineering (Marden) Limited | Manufacturing | 2015 |
| Epic Plumbing Limited | Manufacturing | 2005 |
| Epos Audio UK Limited | Wholesale & retail | 2018 |
| Equalize Construction Ltd | Construction | 2021 |
| Equanimity Associates Limited | Professional & scientific | 2024 |
| Equi-It Limited | Information & communication | 2016 |
| Equity Life Limited | Financial services | 2007 |
| Equity Life UK Limited | Financial services | 2007 |
| Equity Security Promotions Ltd | Administrative & support | 2019 |
| ERDO83 Ltd | Transport & logistics | 2017 |
| Ergin Trading Ltd | Wholesale & retail | 2024 |
| Ergocom Limited | Health & social care | 2008 |
| Eric Mattheeuws UK Limited | Transport & logistics | 1990 |
| Erictel UK Ltd | Information & communication | 2022 |
| Erixstone Construction Ltd | Construction | 2024 |
| ERK Limited | Transport & logistics | 2025 |
| Ernest Homes Kent Limited | Real estate | 2025 |
| Eroom Holdings Ltd | Professional & scientific | 2007 |
| Error Guard Solutions Limited | Information & communication | 2024 |
| ES Old Co Limited | Other services | 2018 |
| ES Restoration Ltd | Construction | 2024 |
| ESB Accounting Services Limited | Professional & scientific | 2020 |
| Escape Hub Limited | Arts & recreation | 2017 |
| Escape Kent Prison Island Limited | Information & communication | 2018 |
| Escapes by Ebonie Ltd | Administrative & support | 2023 |
| ESF Fire Protection Services UK Ltd | Public administration | 2024 |
| Esgyn.Co Ltd | Information & communication | 2026 |
| Esi-Bms Ltd | Professional & scientific | 2026 |
| Espoire Ltd | Health & social care | 2023 |
| Esprit International Limited | Professional & scientific | 1989 |
| Esquire Print Limited | Manufacturing | 2003 |
| Essan-K Planning Limited | Administrative & support | 2003 |
| Essel Innovation and Development Services Limited | Manufacturing | 2020 |
| Essentially London Ltd | Administrative & support | 2014 |
| Essex Auction House Limited | Wholesale & retail | 2020 |
| Essn Strong Ltd | Wholesale & retail | 2019 |
| Estella Boutique Limited | Wholesale & retail | 2014 |
| Estudio Limited | Real estate | 2003 |
| Esty Consultancy Limited | Health & social care | 2025 |
| ET Butcher Takeaway Restaurant Ltd | Wholesale & retail | 2023 |
| Et-C Repairs Ltd | Wholesale & retail | 2019 |
| ETA Transport Ltd | Transport & logistics | 2020 |
| ETE Electrical Contractors Limited | Construction | 2002 |
| Etebar Direct Supplies Ltd | Wholesale & retail | 2024 |
| Etech Gadgets Ltd | Wholesale & retail | 2024 |
| Eternal Health Enterprises Limited | Wholesale & retail | 2023 |
| Ethenham Park Limited | Real estate | 2001 |
| Ether Creative Limited | Information & communication | 2010 |
| Ethica Consultants Limited | Financial services | 2010 |
| Ethical HR Solutions Ltd | Administrative & support | 2018 |
| Ethnicsupermarket Ltd | Wholesale & retail | 2020 |
| Etica Consulting Ltd | Professional & scientific | 2022 |
| ETJ Electrical Limited | Construction | 2016 |
| Etwelle Garage Ltd | Administrative & support | 2023 |
| EU Orang E-Service Ltd | Wholesale & retail | 2023 |
| Eunawo Company Limited | Education | 2025 |
| Eunomia 999 Limited | Information & communication | 2017 |
| Euro Car Tyres Ltd | Wholesale & retail | 2016 |
| Euro-Bpo Limited | Information & communication | 2012 |
| Eurolever Architectural Hardware Limited | Manufacturing | 1999 |
| Eurolever Manufacturing Limited | Financial services | 2013 |
| European Agricultural Commodities Limited | Other services | 2014 |
| European Arts Company Ltd | Arts & recreation | 1993 |
| European Food Suppliers Limited | Administrative & support | 1997 |
| European Moving and Storage Ltd | Manufacturing | 2023 |
| Europet Voyage Ltd | Transport & logistics | 2024 |
| Europlant Rentals Limited | Administrative & support | 1991 |
| EV Home Charge Limited | Construction | 2019 |
| Evander Property Group Ltd | Real estate | 2025 |
| Evaneill Support Services Limited | Education | 2013 |
| Evans & Langford Consultants Limited | Professional & scientific | 2022 |
| Evans Appliances Limited | Wholesale & retail | 2019 |
| Evegate FS (UK) Ltd | Financial services | 2007 |
| Evenbetter Services Ltd | Construction | 2022 |
| Event by EG Ltd | Hospitality | 2023 |
| Eventus Creative Ltd | Manufacturing | 2023 |
| Evergreen PD Limited | Real estate | 2022 |
| Everness Limited | Construction | 2019 |
| Everon UK Limited | Administrative & support | 2009 |
| Everroad Logistics Ltd | Transport & logistics | 2025 |
| Everts Construction Limited | Construction | 2023 |
| Everyman Construction Services Limited | Construction | 1975 |
| Everyone Fitness Ltd | Extraterritorial | 2021 |
| Everystep Private Limited | Health & social care | 2022 |
| Everything Apps Ltd | Information & communication | 2018 |
| Evicom Honey Ltd | Wholesale & retail | 2023 |
| Evilarina Ltd | Transport & logistics | 2025 |
| EVM (Holdings) Limited | Wholesale & retail | 2014 |
| EVO London Ltd | Administrative & support | 2014 |
| Evolution Design and Digital Ltd | Administrative & support | 2018 |