| Straight Forward Publishing Group Limited | Information & communication | 2016 |
| Straight Forward Recordings Limited | Information & communication | 2017 |
| Straightjacket Limited | Information & communication | 1998 |
| Stranfield Financial Services Ltd | Professional & scientific | 2026 |
| Strategic Commercial Consulting Limited | Professional & scientific | 2025 |
| Strategic Marketing Insights Ltd | Professional & scientific | 2022 |
| Strategic Planning Consultancy LLP | | 2006 |
| Strategic Vision (Incorporated) Emea Limited | Professional & scientific | 1994 |
| Strategicfoundry Ltd | Information & communication | 2025 |
| Stratton Fortis Limited | Professional & scientific | 2026 |
| Stratx Solutions Limited | Professional & scientific | 2024 |
| Strawberry Care Limited | Health & social care | 2012 |
| Strawberry Girl Records Limited | Arts & recreation | 2009 |
| Straya Management Ltd | Real estate | 2026 |
| Stream View Management Limited | Households | 2000 |
| Streamline Executive Travel Limited | Extraterritorial | 2006 |
| Streamline Taxis Limited | Transport & logistics | 2002 |
| Street Food by Easydine Limited | Hospitality | 2023 |
| Street Sixty Communications Limited | Professional & scientific | 2018 |
| Streetwear Ltd | Transport & logistics | 2023 |
| Strettons Protect Limited | Financial services | 2026 |
| Stringer and Sons Limited | Construction | 1997 |
| Striped Leopard Accountancy Ltd | Professional & scientific | 2013 |
| Striving Minds Limited | Health & social care | 2026 |
| Strom Technologies Ltd | Administrative & support | 2019 |
| Strong Core Logistics Ltd | Transport & logistics | 2024 |
| Strongfast Global Ltd | Wholesale & retail | 2012 |
| Stroon Ltd | Information & communication | 2023 |
| Structura Interiors Ltd | Construction | 2024 |
| STS Thermal Solutions Limited | Professional & scientific | 2015 |
| Stuart J. Daws & Co. Limited | Wholesale & retail | 1987 |
| Stuart Lamprell Limited | Manufacturing | 2013 |
| Stubbingtons Co Ltd | Financial services | 2022 |
| Student and Rental Group Ltd | Construction | 2018 |
| Student Places Limited | Real estate | 1996 |
| Studio 06 Events Ltd | Real estate | 2024 |
| Studio 06 Ltd | Arts & recreation | 2021 |
| Studio AJW Limited | Wholesale & retail | 2025 |
| Studio at 85 Ltd | Real estate | 2026 |
| Studio Caltagirone Ltd | Professional & scientific | 2025 |
| Studio Covalance Ltd | Professional & scientific | 2025 |
| Studio Dance Company Limited | Arts & recreation | 2017 |
| Studio Dope Ltd | Information & communication | 2023 |
| Studio Fifty Eight Ltd | Other services | 2023 |
| Studio Glatzhofer Ltd | Professional & scientific | 2026 |
| Studio Perucchetti Ltd. | Other services | 2024 |
| Studio RT Limited | Wholesale & retail | 2004 |
| Studio Tashima Ltd | Professional & scientific | 2014 |
| Studrep Ltd | Administrative & support | 2024 |
| Studymedical Limited | Education | 2024 |
| Sturdee Club Developments Limited | Construction | 2025 |
| Sturridge Medical & Surgical Ltd | Health & social care | 2015 |
| Styche & Co Investments Limited | Professional & scientific | 2024 |
| Subcogx Europe Limited | Professional & scientific | 1995 |
| Subcogx UK Limited | Professional & scientific | 2005 |
| Submain Electrical Contractors Limited | Construction | 2010 |
| Submission Technology Limited | Information & communication | 2002 |
| Success Kitchen Consulting Ltd | Professional & scientific | 2018 |
| SUCCESS24 Ltd | Wholesale & retail | 2024 |
| Sudbrooke Site Services Limited | Administrative & support | 2016 |
| Suds and Sisters Cleaning Company Ltd | Administrative & support | 2026 |
| Suha Properties Limited | Real estate | 2012 |
| SUI76 Limited | Administrative & support | 2025 |
| Suiram Handyman Service Ltd | Construction | 2024 |
| Sulk Youth Limited | Information & communication | 2019 |
| Sumaianiaz Limited | Financial services | 2023 |
| Summer Break Park Ltd | Hospitality | 2020 |
| Summersun Court Management Company Limited | Households | 2017 |
| Summit Capital Mortgages LLP | | 2014 |
| Summit Choice Ltd | Wholesale & retail | 2025 |
| Sumudu Ventures Limited | Information & communication | 2018 |
| Sumzi Ltd | Real estate | 2022 |
| Sun Bear Films Ltd | Information & communication | 2018 |
| Sun KEE Maidstone Limited | Hospitality | 2018 |
| Sun Project Management Consultancy Ltd | Wholesale & retail | 2020 |
| Sunami Consulting Ltd | Administrative & support | 2025 |
| Sunny Cabs Ltd | Transport & logistics | 2025 |
| Sunny Field Sells Limited | Wholesale & retail | 2024 |
| Sunnyside Building Services Limited | Construction | 2010 |
| Sunrise Cafe (Dover) Ltd | Hospitality | 2020 |
| Sunrise Day Nursery (Langley) Limited | Education | 2007 |
| Sunset Bikes Limited | Wholesale & retail | 2024 |
| Sunshine Aspects Limited | Other services | 2005 |
| Sunshine WOK Limited | Hospitality | 2023 |
| Super Cleaning Pro Ltd | Administrative & support | 2020 |
| Super Electronic Machines Ltd | Information & communication | 2012 |
| Super Generation Ltd | Information & communication | 2021 |
| Super Micro Foods Ltd | Administrative & support | 2017 |
| Super Pizza Sandling Limited | Hospitality | 2026 |
| Super Pizzas Maidstone UK Ltd | Hospitality | 2025 |
| Super Shwarma Ltd | Hospitality | 2025 |
| Supercar Finance Limited | Extraterritorial | 2005 |
| Supermod Ltd | Construction | 2021 |
| Supertech Advisory Ltd | Professional & scientific | 2018 |
| Supplii Ltd | Wholesale & retail | 2020 |
| Supply Chain Technologies Limited | Extraterritorial | 1994 |
| Supported Housing in Partnership | Health & social care | 2011 |
| Supporting Sustainable Business Limited | Professional & scientific | 2006 |
| Supreme Clean Car Washing Limited | Administrative & support | 2018 |
| Surefit Install Ltd | Construction | 2025 |