| Soknic Limited | Information & communication | 2012 |
| Solantra Ltd | Transport & logistics | 2018 |
| Solar Gates UK Ltd | Administrative & support | 2006 |
| Solar Magneto Ltd | Construction | 2016 |
| Solar Shield Limited | Construction | 1985 |
| Solarin TM Ltd | Construction | 2023 |
| Solaris Installations Limited | Construction | 2010 |
| Sole Copy Ltd | Professional & scientific | 2025 |
| Solid Homes Ltd | Construction | 2024 |
| Solidoak Properties Limited | Construction | 2001 |
| Solmco Limited | Construction | 2011 |
| Solo Kent Services Limited | Administrative & support | 2008 |
| Solo Mission Ltd | Professional & scientific | 2019 |
| Solo Plumbing and Bathrooms Ltd | Construction | 2023 |
| Solo Protection Group Ltd | Administrative & support | 2023 |
| Solumasa Limited | Real estate | 2023 |
| Solutioniser Ltd | Construction | 2023 |
| Solutions by DRE Limited | Other services | 2018 |
| Solvochem (UK) Limited | Extraterritorial | 2019 |
| Somerset Project Management Limited | Construction | 2021 |
| Somerset Property Ventures Limited | Construction | 2015 |
| Something Good Maidstone CIC | Hospitality | 2016 |
| Somethingood.Today Ltd | Professional & scientific | 2023 |
| Sonalis Imaging Limited | Professional & scientific | 2017 |
| Sonario Active Fire Protection Ltd | Administrative & support | 2024 |
| Sonik Logistics Ltd | Transport & logistics | 2020 |
| Sophia Fanciulli Interior Design Limited | Professional & scientific | 2022 |
| Sophia Looney Associates Limited | Professional & scientific | 2017 |
| Sophie Ward Consultancy Ltd | Professional & scientific | 2024 |
| Sophie's Snack Bar Limited | Hospitality | 2026 |
| Sophiestream Ltd | Information & communication | 2026 |
| Sophrology London Limited | Health & social care | 2018 |
| Sorex Group Limited | Construction | 2018 |
| Sorexa Ltd | Wholesale & retail | 2025 |
| Sort Trans Ltd | Construction | 2017 |
| Sothertons Limited | Professional & scientific | 2005 |
| Soul & Skin Beauty, Massage & Aesthetics Ltd | Other services | 2026 |
| Soul Taste Limited | Hospitality | 2021 |
| Sound Algorithm Ltd | Information & communication | 2021 |
| Sound Production Live Ltd | Hospitality | 2022 |
| Sound Shoeing Limited | Agriculture & fishing | 2023 |
| Source Fire Protection Limited | Professional & scientific | 2015 |
| Sourcing Vintage Ltd | Wholesale & retail | 2025 |
| South East Electrics Ltd | Construction | 2020 |
| South East Game Shooting Limited | Arts & recreation | 2018 |
| South East Garden Rooms Limited | Administrative & support | 2025 |
| South East Home Improve Limited | Construction | 2025 |
| South East Services (Kent) Ltd | Energy | 2012 |
| South East Specialist Installation Team Ltd | Public administration | 2024 |
| South East Steel Ltd | Administrative & support | 2009 |
| South Eastern Auto Electrical Services Limited | Wholesale & retail | 1949 |
| South Eastern Building Services Limited | Construction | 2024 |
| South Eastern Solutions Limited | Health & social care | 2016 |
| South Eastern Tennis Limited | Arts & recreation | 2010 |
| South Lodge Residents Association Limited | Households | 1989 |
| Southeast Developers Ltd | Construction | 2011 |
| Southeast Single PLY Ltd | Construction | 2020 |
| Southeast Trailers Limited | Wholesale & retail | 2017 |
| Southern Adhesives Ltd | Construction | 2012 |
| Southern Building Developments Limited | Construction | 2016 |
| Southern Estates Holdings Limited | Real estate | 2007 |
| Southern Estates Services Limited | Real estate | 2019 |
| Southern GEM Ltd | Hospitality | 2022 |
| Southern Hardware Supply Limited | Wholesale & retail | 1991 |
| Southern Interiors Ltd | Construction | 2019 |
| Southern Lightning Engineers Limited | Construction | 1993 |
| Southern Microscope Limited | Professional & scientific | 2016 |
| Southern Microscope Veterinary Services Ltd | Manufacturing | 2002 |
| Southern Planters Ltd | Administrative & support | 2012 |
| Southern Property Estates Limited | Real estate | 2021 |
| Southern Segway Limited | Arts & recreation | 2007 |
| Southern Signs Ltd | Manufacturing | 2014 |
| Southern Television Limited | Information & communication | 2004 |
| Southern Vehicle Security Ltd | Wholesale & retail | 2021 |
| Southon Brickwork Limited | Administrative & support | 2011 |
| Southshore Homes Ltd | Real estate | 2025 |
| Sovereign International Metals & Alloys Ltd | Wholesale & retail | 2020 |
| Sovereign Mortgage Services Limited | Other services | 2016 |
| Sovereign Property Facilities Ltd | Administrative & support | 2012 |
| Sovereign Tutors Limited | Education | 2016 |
| Sovereigns Freehold Limited | Real estate | 2002 |
| SP & H Trading Limited | Wholesale & retail | 2021 |
| SP Structures Limited | Construction | 2011 |
| Space 2 BE ME Ltd | Information & communication | 2010 |
| Space Construction London Ltd | Construction | 2014 |
| Space Recruitment International Ltd | Administrative & support | 2004 |
| Spaceflame Ltd. | Arts & recreation | 2022 |
| Spanarc Valves and Controls Limited | Extraterritorial | 1998 |
| Spangles Education Limited | Education | 2016 |
| Spar Intellec Limited | Information & communication | 2018 |
| Spark UP Design Ltd | Professional & scientific | 2015 |
| Sparkle Animation Limited | Information & communication | 2011 |
| Sparkling Klean Kent Ltd | Administrative & support | 2022 |
| Sparkwise Cleaning Limited | Administrative & support | 2025 |
| Sparkz Marketing Ltd | Professional & scientific | 2021 |
| Spartan Retail Support Limited | Extraterritorial | 2013 |
| Spartan Security and Fire Ltd | Wholesale & retail | 2025 |
| Spartan Sport Development Ltd | Education | 2019 |
| Specialised Housing & Care Ltd | Health & social care | 2017 |
| Spectre Psychotherapy Limited | Health & social care | 2024 |