| RWS Global Holdings Limited | Financial services | 2023 |
| RWS Group Limited | Professional & scientific | 1981 |
| RWS Holdings PLC | Financial services | 1994 |
| RWS Information Limited | Information & communication | 1971 |
| RWS Translations Limited | Professional & scientific | 1972 |
| RWS UK Holding Co Limited | Professional & scientific | 2015 |
| RY Property Group Ltd | Real estate | 2026 |
| Ryan Ltd | Information & communication | 2007 |
| Ryton Waste Disposal Limited | Extraterritorial | 1987 |
| S B Cook Electrical Contractors Limited | Construction | 2021 |
| S Chana Contractors Ltd | Manufacturing | 2023 |
| S E L International Limited | Professional & scientific | 1997 |
| S G M Sidhu Ltd | Professional & scientific | 2013 |
| S K WIN Limited | Other services | 2009 |
| S Noone Building Services Limited | Construction | 2012 |
| S O'Neill Plumbing and Heating Limited | Construction | 2014 |
| S SUB Limited | Professional & scientific | 1988 |
| S W Auto Recycling Limited | Wholesale & retail | 2016 |
| S&A Property Services Limited | Real estate | 2020 |
| S&J Property Services Limited | Other services | 2004 |
| S&L Lifts Limited | Manufacturing | 2011 |
| S&N Associates Ltd | Professional & scientific | 2023 |
| S&P Bridgewater LLP | | 2018 |
| S&P Riar Transport Limited | Transport & logistics | 2025 |
| S-Cubed Solutions Limited | Information & communication | 2018 |
| S. Invest Ltd | Real estate | 2024 |
| S.B.C Locum Limited | Professional & scientific | 2020 |
| S.D.S. Leisure Enterprises Limited | Real estate | 1978 |
| S.E Mechanical Engineering Ltd | Professional & scientific | 2017 |
| S.Gurd Property Solutions Ltd | Construction | 2011 |
| S.M. ALI (Anaesthetists) Limited | Health & social care | 2010 |
| S.R. Jones & SON Limited | Construction | 2006 |
| S.S. Khehar Accountancy Services Limited | Professional & scientific | 2003 |
| S10 Group Ltd | Information & communication | 2026 |
| S2 Holdings Limited | Real estate | 2017 |
| S2O Productions Limited | Information & communication | 2011 |
| S4B (UK) Ltd | Professional & scientific | 2011 |
| S4S Security Seals Limited | Wholesale & retail | 2014 |
| SA 2017 Limited | Real estate | 1987 |
| SA Chauffeurs Ltd | Transport & logistics | 2023 |
| Saanuvip Ltd | Real estate | 2025 |
| Saarv Ltd | Information & communication | 2015 |
| SAB Psychology Ltd | Professional & scientific | 2025 |
| Sabella Interiors Limited | Other services | 2016 |
| Sabine Antonia Ltd | Professional & scientific | 2013 |
| Sachshal Ltd | Wholesale & retail | 2015 |
| Sacred Artefacts Ltd | Wholesale & retail | 2023 |
| Sadler & Frost Ltd | Professional & scientific | 2020 |
| Sadler Greenwood Limited | Administrative & support | 2013 |
| Safaiwala Ltd | Administrative & support | 2024 |
| Safari Property Limited | Real estate | 2016 |
| Safe Fixing Ltd | Construction | 2010 |
| Safe Fixing (Property) Ltd | Real estate | 2014 |
| Safe House Windows Ltd | Manufacturing | 2012 |
| Safe Shield Software Limited | Professional & scientific | 2026 |
| Safeland Security Ltd | Administrative & support | 2025 |
| Safire Consulting Ltd | Professional & scientific | 2011 |
| Sagacity Consultants Ltd | Professional & scientific | 2017 |
| Sage & Stone Ltd | Wholesale & retail | 2021 |
| Saheel Consultancy Limited | Financial services | 2018 |
| Sahrova Limited | Wholesale & retail | 2026 |
| SAI Seva UK Limited | Other services | 2019 |
| SAI Vvimala Solutions Ltd | Information & communication | 2020 |
| Sailtown Limited | Professional & scientific | 2004 |
| Saira Majid Accountants Limited | Professional & scientific | 2015 |
| Sajf Traders Ltd | Wholesale & retail | 2024 |
| Sakube Ltd | Real estate | 2021 |
| Sales Builder Europe Ltd | Professional & scientific | 2024 |
| Sales Review Limited | Administrative & support | 2022 |
| Salience Training & Consultancy Ltd | Professional & scientific | 2025 |
| Salmon Blaze Ltd | Professional & scientific | 2023 |
| Salmon Cyber Ltd | Wholesale & retail | 2026 |
| Salon Euphoria Ltd | Other services | 2021 |
| Salon Fresh Limited | Other services | 2015 |
| Salter Associates Ltd | Professional & scientific | 2023 |
| Saltlands Carpentry Limited | Manufacturing | 2025 |
| SAM Housing Ltd | Real estate | 2021 |
| Samanvi Biotech Ltd | Information & communication | 2022 |
| Samara Ventures Limited | Financial services | 2026 |
| Same Day Goods Ltd | Transport & logistics | 2017 |
| Samraj Limited | Real estate | 2002 |
| Samuel E Lewis Ltd | Professional & scientific | 2019 |
| Samuel Wilkinson & Sons Limited | Professional & scientific | 1961 |
| Samurai Kickboxing Jersey Ltd | Education | 2021 |
| Sana Mechanical and Electrical Limited | Construction | 2012 |
| Sancoshipping Ltd | Transport & logistics | 2017 |
| Sandata Ltd | Information & communication | 2019 |
| Sandc Practice Management Ltd | Professional & scientific | 2013 |
| Sanderson Park Resident Management Company Limited | Households | 2021 |
| Sandford Oxford Limited | Construction | 2016 |
| Sandip Gill Ltd | Professional & scientific | 2014 |
| Sandsiv Group Limited | Professional & scientific | 2014 |
| Sandsiv UK Limited | Professional & scientific | 2015 |
| Sanjay Gondkar Consulting Limited | Professional & scientific | 2015 |
| Sankla & Associates Ltd | Professional & scientific | 2026 |
| Sansmart Ltd | Real estate | 2022 |
| Sansome & Co Properties Ltd | Real estate | 2017 |
| Sansome Building Services Ltd | Professional & scientific | 2017 |
| Sansubs Limited | Hospitality | 2003 |
| Santé Holdings Limited | Financial services | 2015 |