| M2M Business Consulting Ltd | Professional & scientific | 2025 |
| M4 Wavepower Ltd | Professional & scientific | 2012 |
| M60 Digital Ltd | Information & communication | 2009 |
| Maan & Company Limited | Health & social care | 2011 |
| MAC Dental Centre Limited | Administrative & support | 2011 |
| MAC Excavations & Groundworks Ltd | Construction | 2013 |
| MAC Flames Ltd | Hospitality | 2019 |
| MAC Flames Macclesfield Ltd | Hospitality | 2025 |
| Macc Cleaners Ltd | Administrative & support | 2020 |
| Macc Foods Ltd | Hospitality | 2025 |
| Macc Football Club Limited | Arts & recreation | 2020 |
| Macc Lawnmower Services LLP | | 2016 |
| Macc Mouse Homes Limited | Real estate | 2013 |
| Macc Mowers Ltd | Other services | 2025 |
| Macc Scrap Metals Ltd | Water & waste | 2020 |
| Macc Town Kebab Ltd | Hospitality | 2023 |
| Macc Tyres Limited | Wholesale & retail | 2015 |
| Macclandscapes Ltd | Wholesale & retail | 2025 |
| Macclesfield Alterations Ltd | Professional & scientific | 2023 |
| Macclesfield Bearings Limited | Wholesale & retail | 1987 |
| Macclesfield Beer Festival Limited | Administrative & support | 2023 |
| Macclesfield Burger Ltd | Hospitality | 2025 |
| Macclesfield Car Sales Ltd | Wholesale & retail | 2021 |
| Macclesfield Community Artspace | Arts & recreation | 2012 |
| Macclesfield Community Garden Centre | Education | 2008 |
| Macclesfield Community Tree Nursery CIC | Agriculture & fishing | 2023 |
| Macclesfield Conservative Club Limited | Real estate | 1928 |
| Macclesfield Cricket Club Limited | Arts & recreation | 1998 |
| Macclesfield Culture Collective CIC | Arts & recreation | 2026 |
| Macclesfield Day Nursery Limited | Health & social care | 2015 |
| Macclesfield FC Community Sports Trust Ltd | Education | 2008 |
| Macclesfield Fencing Ltd | Construction | 2023 |
| Macclesfield Golf Club Trading Limited | Arts & recreation | 2015 |
| Macclesfield Hospitality Action CIC | Administrative & support | 2021 |
| Macclesfield Hospitality Group Ltd | Hospitality | 2025 |
| Macclesfield Judo Club Limited | Education | 2026 |
| Macclesfield Lawnmower Services Ltd | Manufacturing | 2015 |
| Macclesfield Lawnmowers Ltd | Other services | 2025 |
| Macclesfield LL Happy House Ltd | Hospitality | 2024 |
| Macclesfield Lock & Safe Ltd | Administrative & support | 2024 |
| Macclesfield Maintenance Ltd | Construction | 2016 |
| Macclesfield Medical Writing Ltd. | Professional & scientific | 2015 |
| Macclesfield Model Engineers Supplies Limited | Wholesale & retail | 2005 |
| Macclesfield Motors Ltd | Wholesale & retail | 2021 |
| Macclesfield Performance Ltd | Other services | 2013 |
| Macclesfield Pilates and Yoga Studio Ltd | Arts & recreation | 2020 |
| Macclesfield Properties Limited | Real estate | 2002 |
| Macclesfield Property Hub Limited | Real estate | 2018 |
| Macclesfield Rainbow Taste Ltd | Hospitality | 2025 |
| Macclesfield Repair Café C.I.C. | Other services | 2025 |
| Macclesfield Short Stays Ltd | Real estate | 2019 |
| Macclesfield Tools Ltd | Construction | 2025 |
| Macclesfield Town Basketball Club Community Interest Company | Arts & recreation | 2022 |
| Macclesfield Town Football Club,Limited | Arts & recreation | 1946 |
| Macclesfield Trade Centre Limited | Wholesale & retail | 2018 |
| Macclesfield Tutorial College Limited | Education | 2018 |
| Macclesfield Ukrainian AID Community Interest Company | Health & social care | 2023 |
| Macclesfield Visionplus Limited | Wholesale & retail | 1990 |
| Maccs Discount Ltd | Wholesale & retail | 2025 |
| Macmakeovers Limited | Professional & scientific | 2025 |
| Macrowill Plastic Engineering (UK) Ltd | Wholesale & retail | 2017 |
| Mactex Limited | Wholesale & retail | 1993 |
| Mactex Properties (2004) Limited | Administrative & support | 2004 |
| Mactex Properties Limited | Real estate | 1976 |
| Madbarz Holdings Ltd | Financial services | 2023 |
| Madbarz Limited | Administrative & support | 2016 |
| Madesco Limited | Construction | 2018 |
| Madic Limited | Financial services | 2002 |
| Madisonyoga Limited | Health & social care | 2025 |
| Maenan Abbey Hotel Limited | Hospitality | 1997 |
| Magenta Leaf Ltd | Professional & scientific | 2018 |
| Magic Mountain Limited | Extraterritorial | 1987 |
| Magnus Ltd | Manufacturing | 2019 |
| Magnus Scales Ltd | Manufacturing | 2019 |
| Mahi S Properties Ltd | Real estate | 2025 |
| Mahira Enterprises Ltd | Professional & scientific | 2018 |
| MAI UK Holdings Limited | Professional & scientific | 2006 |
| Maid in Cheshire Ltd | Households | 2019 |
| Maintenance Supplies Contracts Limited | Construction | 2007 |
| Maintenance Supplies Limited | Wholesale & retail | 2003 |
| Maisontwentyseven Limited | Professional & scientific | 2025 |
| MAJ Digital Ltd | Information & communication | 2022 |
| Majorvision Limited | Extraterritorial | 1992 |
| MAK D Industrial Services Ltd | Administrative & support | 2022 |
| Make IT Macclesfield Community Interest Company | Professional & scientific | 2013 |
| Make-Up Trainees Ltd | Education | 2026 |
| Malbec Property Limited | Real estate | 2019 |
| Malbec Property Solutions Limited | Real estate | 2021 |
| Maleson Consultancy Limited | Administrative & support | 2024 |
| Maleson Limited | Real estate | 2022 |
| Malik Consulting Engineers Ltd | Professional & scientific | 2026 |
| Mallia Properties Ltd | Real estate | 2025 |
| Malmanz Limited | Health & social care | 2021 |
| Mams Pharma Services Ltd | Professional & scientific | 2014 |
| Manaris Limited | Hospitality | 2024 |
| Manchester Advanced Intelligent Equipment Research & Innovation Centre Ltd | Manufacturing | 2020 |
| Manchester Flooring Company Limited | Wholesale & retail | 2002 |
| Manchester Medical Academy Limited | Education | 2024 |
| Mango Hedgehog Ltd | Hospitality | 2018 |
| Manor Retail Group Limited | Wholesale & retail | 2017 |