| Douglas Fenton Limited | Real estate | 1942 |
| Douglas Forsyth Limited | Professional & scientific | 2011 |
| Dowland Ltd | Hospitality | 2024 |
| DP & K Rhodes Limited | Wholesale & retail | 2002 |
| DP Security Solutions Limited | Administrative & support | 2008 |
| DPK Holdings Limited | Financial services | 2022 |
| DR Beth Shepherd Radiology Services Ltd | Health & social care | 2019 |
| DR James Beer Ltd | Health & social care | 2024 |
| DR M a Lucas Limited | Real estate | 2011 |
| DR Mark Sopher Limited | Health & social care | 2010 |
| DR W G Johnson Limited | Health & social care | 2006 |
| Dragon Creativity Ltd | Manufacturing | 2016 |
| Dragon Holdings Limited | Professional & scientific | 1968 |
| Dragonet Marine Systems Ltd. | Manufacturing | 1993 |
| Drake Refurbishment Ltd | Construction | 2012 |
| Draldous Ltd | Professional & scientific | 2026 |
| Dray Mews Cottages Management Company Limited | Households | 2023 |
| Draycott Management Limited | Real estate | 2001 |
| Draycott Surveyors Limited | Professional & scientific | 1991 |
| Dream Oracles Limited | Information & communication | 2022 |
| Dunford Construction Limited | Construction | 1983 |
| Dunver Projects Ltd | Construction | 2015 |
| DUO Coaching Limited | Health & social care | 2010 |
| Durrlock Limited | Real estate | 2016 |
| Dusty Boots Line Dancing Ltd | Education | 2026 |
| Duval Consultancy Ltd | Administrative & support | 2009 |
| Dépaysement Ltd | Administrative & support | 2021 |
| E-Motion Marine Limited | Wholesale & retail | 2018 |
| E.G.Dunford Limited | Construction | 1962 |
| Eadie Cairns Limited | Real estate | 2016 |
| Eadie Cairns Properties Limited | Real estate | 2024 |
| EAR Clinic (Lymington) Ltd | Health & social care | 2018 |
| Eastwoods Equestrian Ltd | Agriculture & fishing | 2020 |
| Easy AS PIE Limited | Administrative & support | 2017 |
| EAT Pizza South Coast Ltd | Hospitality | 2020 |
| Eating Together PUB Company Limited | Hospitality | 2018 |
| EBB Tide Investments Limited | Energy | 2003 |
| Ebenezer Support Ltd | Health & social care | 2024 |
| ECM (Lymington) Ltd | Households | 2014 |
| Ecoclub Ltd | Construction | 2020 |
| Edala Properties Ltd | Hospitality | 2020 |
| Edensfield Limited | Real estate | 1995 |
| EDS Trans Ltd | Transport & logistics | 2021 |
| Edward Doherty & Sons Limited | Real estate | 1938 |
| Edwards Heavies Limited | Wholesale & retail | 2011 |
| Efford Construction Ltd | Construction | 2019 |
| Eichner Studio Limited | Information & communication | 2013 |
| Eight Wellness Limited | Health & social care | 2024 |
| EJH Development Properties Ltd | Construction | 2021 |
| Elandem Ltd | Professional & scientific | 2018 |
| Elate Limited | Administrative & support | 1998 |
| Elderflower Leisure Limited | Hospitality | 2013 |
| Electric Gates New Forest Ltd | Manufacturing | 2015 |
| Elektrex Limited | Professional & scientific | 2022 |
| Elemental Industries Limited | Information & communication | 2012 |
| ELEVE11 Holdings Limited | Financial services | 2022 |
| Elford Environmental Services Ltd | Administrative & support | 2012 |
| Elliotts Retail Holdings Limited | Wholesale & retail | 2014 |
| Elliotts Retailing Limited | Wholesale & retail | 2014 |
| Elmbaron Limited | Households | 1984 |
| Eltec Services Ltd | Administrative & support | 2018 |
| Embed Holdings Limited | Manufacturing | 2022 |
| Emerald Bond Management Company Limited | Professional & scientific | 2017 |
| Emerald Care Providers Ltd | Health & social care | 2021 |
| Emerald MEP Design UK Limited | Professional & scientific | 2017 |
| Emerald Supplies Holdings Limited | Wholesale & retail | 2022 |
| Emerald Supplies Limited | Wholesale & retail | 1989 |
| Enabled Education CIC | Education | 2020 |
| Encompass Events Ltd | Administrative & support | 2009 |
| Entegra DSP Limited | Real estate | 2010 |
| Environmental Expertise Limited | Professional & scientific | 2013 |
| EOS Architecture Limited | Professional & scientific | 2021 |
| Equate Business Solutions Limited | Information & communication | 2003 |
| Equiamore Ltd | Wholesale & retail | 2025 |
| Eric's PUB Ltd | Hospitality | 2021 |
| Escalier 39 Limited | Administrative & support | 2012 |
| Escape Yachting Ltd | Administrative & support | 2010 |
| ESH Estates Ltd | Real estate | 2014 |
| Ethos Outcomes Ltd | Health & social care | 2026 |
| Etonhurst Management Ltd | Real estate | 2025 |
| Euphoria Group London Ltd | Hospitality | 2024 |
| Eurolink Catering Equipment Limited | Manufacturing | 2003 |
| Europa Composites Ltd | Manufacturing | 2013 |
| Europe Finance Consulting Limited | Administrative & support | 1999 |
| European Stone Importers Limited | Extraterritorial | 1987 |
| Evans (Stage & Studio Engineering) Limited | Manufacturing | 1981 |
| Event Management Group Limited | Extraterritorial | 2003 |
| EVENTS4SPORT Limited | Arts & recreation | 2024 |
| Every Cloud Accountancy and Bookkeeping Ltd | Professional & scientific | 2017 |
| Evolve Corporation Limited | Real estate | 2013 |
| Evolved Research and Consulting Ltd | Professional & scientific | 2019 |
| Excel Adhesives Ltd | Manufacturing | 2006 |
| Excellerate Limited | Professional & scientific | 2018 |
| Executive Estates (Hampshire) Limited | Construction | 1995 |
| Executives in Emerging Markets Limited | Extraterritorial | 2010 |
| Exeter Health Solutions Ltd | Health & social care | 2013 |
| Explorer Support Limited | Administrative & support | 2026 |
| F & Z Storage Limited | Real estate | 2022 |
| F H Management 2010 Limited | Real estate | 2010 |
| F Noble Services Limited | Extraterritorial | 2012 |