| Reap Coaching Ltd. | Arts & recreation | 2021 |
| REB Motorsport Ltd | Manufacturing | 2023 |
| Rebreatherpro Training Limited | Other services | 2014 |
| Recassifi Ltd | Wholesale & retail | 2025 |
| Red Reindeer Productions Ltd | Information & communication | 2002 |
| Redland Finance Holdings Limited | Professional & scientific | 1972 |
| Redland Magnesia Limited | Extraterritorial | 1952 |
| Redrunner Ltd | Professional & scientific | 2016 |
| Reedswood Park Management Company Limited | Households | 2023 |
| Refined Construction (Leicester) Ltd | Construction | 2011 |
| Refunded Ltd | Professional & scientific | 2024 |
| Regal Fabrications (Coventry) Limited | | 1983 |
| Regent Street Storage Limited | Information & communication | 2015 |
| Regerplatz Ltd | Wholesale & retail | 2023 |
| Regional Foster Families Ltd | Health & social care | 2001 |
| Reilly's Express Delivery Ltd | Transport & logistics | 2022 |
| Reliable Haulage Limited | Information & communication | 1990 |
| Renew Psychology Ltd | Health & social care | 2024 |
| Resl (Southampton) Realisations Limited | Professional & scientific | 2007 |
| Resolution HR Ltd | Administrative & support | 2021 |
| Respiratory Sleep Ltd | Wholesale & retail | 2019 |
| Reverance Life Ltd | Health & social care | 2026 |
| Revival Swimwear AID Limited | Manufacturing | 2023 |
| REX Regum HQ Ltd | Wholesale & retail | 2024 |
| Rezk's Ltd | Health & social care | 2025 |
| RGS Landscaping Ltd | Administrative & support | 2022 |
| Rhino Software Ltd | Information & communication | 2015 |
| RHJ Airfield Park Limited | Real estate | 2002 |
| RIA Tunaley Consultancy Limited | Professional & scientific | 2025 |
| Rice Medical Limited | Health & social care | 2017 |
| Rich Mclean Ltd | Construction | 2016 |
| Richard Michael Electrical Limited | Construction | 2015 |
| Richards Al-Chalabi Ltd | Information & communication | 2014 |
| Ricky Bell Ltd | Real estate | 2022 |
| Ride and Drive Lutterworth Ltd | Wholesale & retail | 2025 |
| Ridgeon Network Ltd. | Information & communication | 2009 |
| Ridgeon Ventures Limited | Other services | 2008 |
| Riemer Orthopaedics Ltd | Health & social care | 2019 |
| River Rentals Ltd | Administrative & support | 2017 |
| Riverdale Natural Water Features Limited | Construction | 2022 |
| Riverside Court (Market Harborough) Management Company Limited | Real estate | 2006 |
| Riverstone Homes Midlands Ltd | Construction | 2024 |
| Rivonia Joseph Randall Ltd | Real estate | 2002 |
| Riyaz Shah Oncology Ltd | Health & social care | 2017 |
| Rjem Consulting Limited | Professional & scientific | 2019 |
| RJK Services Ltd | Health & social care | 2026 |
| RK Bisarya Ltd | Health & social care | 2023 |
| Rking Industries Limited | Manufacturing | 2024 |
| RLK Ltd | Information & communication | 2021 |
| RM Surgical Partners Ltd | Health & social care | 2026 |
| RMI (Midlands) Limited | Construction | 2013 |
| RMI Fabrications Limited | Construction | 2021 |
| Robert Dargue Design Studio Ltd | Construction | 2026 |
| Robert Powell Limited | Other services | 2009 |
| Robert Taylor Developments Ltd | Extraterritorial | 2011 |
| Roberts (Leicester) Limited | Wholesale & retail | 2019 |
| Robinsons of Lutterworth Limited | Wholesale & retail | 2015 |
| Rock Associates Investments Limited | Real estate | 2017 |
| Rock Associates Limited | Administrative & support | 2009 |
| Rock Trans Ltd | Transport & logistics | 2024 |
| Rockstar Marketing Group Limited | Hospitality | 2016 |
| ROD Hafner (Consulting) Limited | Professional & scientific | 2020 |
| Roma Numismatics Limited | Wholesale & retail | 2008 |
| Rona Purdham Coaching & Development Limited | Professional & scientific | 2007 |
| Rosapenna Properties Ltd | Real estate | 2023 |
| Roseden Limited | Professional & scientific | 2010 |
| Roseheath Estates Limited | Real estate | 1997 |
| Rotating Plant Measurement Ltd | Professional & scientific | 2018 |
| Rotec Precision Limited | Manufacturing | 1997 |
| Rowan Vehicle Logistics Limited | Construction | 2001 |
| Royal Smithfield Club(The) | Agriculture & fishing | 1900 |
| RS Premium Car Sales Ltd | Wholesale & retail | 2023 |
| RTS Construction Group Limited | Financial services | 2014 |
| RTS Construction Limited | Construction | 2013 |
| RTS Projects Limited | Construction | 2021 |
| Ruban's Medical Ltd | Health & social care | 2022 |
| Ruban's Property Investments Ltd | Real estate | 2025 |
| Rubenji Ltd | Financial services | 2020 |
| Rubens Developments Limited | Real estate | 2008 |
| Ruby Piano Room Ltd | Hospitality | 2019 |
| Ruckmore Ltd | Other services | 2023 |
| Rugby Fireplaces Limited | Wholesale & retail | 2012 |
| Rugby Scaffolding Services Limited | Construction | 2005 |
| Rugged Earth Ltd | Professional & scientific | 2009 |
| Rural Autogates Ltd | Construction | 2014 |
| RV Lock Homes Ltd | Real estate | 2026 |
| S C L FUN Leisure Limited | Arts & recreation | 2017 |
| S Chari Limited | Administrative & support | 2010 |
| S Folan Limited | Other services | 2014 |
| S G N Motors Ltd | Wholesale & retail | 2023 |
| S J Cartwright Ltd | Agriculture & fishing | 2011 |
| S J Print Ltd | Wholesale & retail | 2016 |
| S K Varma Limited | Other services | 2011 |
| S Langlands Limited | Other services | 2011 |
| S P Ford & Co. Limited | Professional & scientific | 2012 |
| S&D Leisure Simulations Ltd | Administrative & support | 2007 |
| S&Df Ltd | Real estate | 2010 |
| S&G Grey Property Ltd | Real estate | 2024 |
| S.H.Popple Limited | Manufacturing | 1946 |
| SA Surgery Limited | Health & social care | 2023 |