| Derco Properties Ltd | Real estate | 2021 |
| Derek Lofty & Associates LLP | | 2007 |
| Derek Lofty Properties Ltd | Real estate | 2007 |
| Derek S. Wood Associates Limited | Wholesale & retail | 1982 |
| Derek's Drive Limited | Transport & logistics | 2014 |
| Dericom Ltd | Construction | 2024 |
| Derma Studios Ltd | Health & social care | 2009 |
| Dermamed Wellbeing Clinic Limited | Other services | 2024 |
| Dermbiopsy Solutions Ltd | Health & social care | 2025 |
| Deroan Utilities Limited | Manufacturing | 2013 |
| Deru Limited | Real estate | 2017 |
| Deru Properties Ltd | Real estate | 2023 |
| Deseronto Management Company Limited | Real estate | 2010 |
| Desi Arts Development Group C.I.C. | Education | 2023 |
| Desi Dine Ltd | Hospitality | 2025 |
| Desi Junction Ltd | Hospitality | 2023 |
| Desi Table Ltd | Hospitality | 2026 |
| Desi Tadka Luton Ltd | Hospitality | 2025 |
| Design and Consult Ltd | Administrative & support | 2023 |
| Design by SI Ltd | Information & communication | 2019 |
| Design Development Project Management Limited | Construction | 2013 |
| Design Universe Ltd | Manufacturing | 2023 |
| Designed to Provoke Ltd | Manufacturing | 2022 |
| Designer by CS Limited | Wholesale & retail | 2025 |
| Designer Labels (Luton) Ltd | Wholesale & retail | 2019 |
| Designer Tiling Ltd | Construction | 2018 |
| Desigra Solutions Limited | Professional & scientific | 2013 |
| Desire Ventures UK LLC Limited | Manufacturing | 2025 |
| Desiring Ltd | Arts & recreation | 2023 |
| Desk Pilot Ltd | Professional & scientific | 2024 |
| Desmwtis Ltd | Real estate | 2014 |
| Dessert House Rushden Ltd | Hospitality | 2024 |
| Dessert Hub Rushden Limited | Manufacturing | 2025 |
| Dessert Island Luton Limited | Hospitality | 2024 |
| Desserts AA Ltd | Hospitality | 2025 |
| Desserts and Shakes Ltd | Hospitality | 2021 |
| Desserts Wizard Limited | Hospitality | 2025 |
| Destiny Enterprises Ltd | Other services | 2011 |
| Detounbeauty Studio Ltd | Other services | 2025 |
| Detoxservice Ltd | Professional & scientific | 2026 |
| DEV Hospitality Ltd | Hospitality | 2025 |
| Devees Global Services UK Limited | Professional & scientific | 2025 |
| Develop Enterprises Ltd | Wholesale & retail | 2022 |
| Development for ALL Research and Consultancy Limited | Professional & scientific | 2023 |
| Developwise CIC | Information & communication | 2021 |
| Devi Singh Ltd | Construction | 2023 |
| Devicesin Solutions UK Limited | Real estate | 2026 |
| Devlin Residential Ltd | Real estate | 2021 |
| Devoted to Care Ltd | Administrative & support | 2016 |
| DEW & DEW Limited | Other services | 2015 |
| Dewan & Partners Limited | Construction | 2025 |
| Dewan Accountants Limited | Professional & scientific | 2020 |
| Dewan Homes Limited | Real estate | 2024 |
| Dewola Global Ltd | Health & social care | 2023 |
| Dexterous Design and Build Limited | Construction | 2023 |
| Deyac Ltd | Construction | 2022 |
| Deza Development Ltd | Construction | 2023 |
| DFA Mechanical Ltd | Administrative & support | 2025 |
| Dfaj Consulting Limited | Information & communication | 2014 |
| DFB Garage Ltd | Other services | 2022 |
| Dfcb Limited | Hospitality | 2023 |
| Dfer Systems Limited | Administrative & support | 2019 |
| DFL Gworks Limited | Construction | 2025 |
| Dfleet Cleaning Ltd | Administrative & support | 2024 |
| DG Motor Commercial Centre Limited | Wholesale & retail | 2020 |
| DG Professionals Ltd | Construction | 2023 |
| DG4CLOUD Ltd | Construction | 2019 |
| DGA Property Investment Ltd | Real estate | 2024 |
| Dgeq Investments Ltd | Real estate | 2023 |
| Dgtl Works Ltd | Information & communication | 2020 |
| DH Luton Property Investments Ltd | Real estate | 2019 |
| DH Solid Brickwork Ltd | Construction | 2025 |
| Dhaka One World Limited | Agriculture & fishing | 2020 |
| Dhamolcorp Ltd | Transport & logistics | 2025 |
| Dhana Limited | Wholesale & retail | 2025 |
| Dhanad Ltd | Financial services | 2022 |
| Dhatterwal Logistics Ltd | Transport & logistics | 2026 |
| Dhbu Ltd | Professional & scientific | 2025 |
| Dhcs Management Limited | Health & social care | 2022 |
| Dhesi Asset Management Limited | Real estate | 2024 |
| DHH (Luton) Limited | Extraterritorial | 2020 |
| DHH Investment Group Ltd | Financial services | 2023 |
| Dhillon Cars Ltd | Wholesale & retail | 2018 |
| Dhillon Estate Ltd | Real estate | 2015 |
| Dhillon Gourav Ltd | Construction | 2025 |
| Dhillon Transportation Limited | Transport & logistics | 2025 |
| Dhillon Trauma Ortho Ltd | Health & social care | 2024 |
| DI Accounting and Advisory Ltd | Professional & scientific | 2026 |
| DI Carlo Construction Ltd | Construction | 2018 |
| DI Construct Solutions Ltd | Construction | 2025 |
| DIA London Limited | Professional & scientific | 2021 |
| Diamond Boys and Girls Limited | Agriculture & fishing | 2024 |
| Diamond Cleaners Bedfordshire Ltd | Administrative & support | 2024 |
| Diamond Coffee Mediterranean Cuisine Ltd | Hospitality | 2024 |
| Diamond CUT Consulting Limited | Professional & scientific | 2015 |
| Diamond Days Childcare Ltd | Education | 2023 |
| Diamond Executive Cars Ltd | Transport & logistics | 2023 |
| Diamond Home Global Ltd | Wholesale & retail | 2026 |
| Diamond Multiserve Ltd | Transport & logistics | 2023 |
| Diamond Plaster's Ltd | Construction | 2022 |