| Diamondpool Limited | Administrative & support | 2000 |
| Dietrich Accounting Ltd | Professional & scientific | 2025 |
| Digi-Construction Ltd | Construction | 2018 |
| Digibit Media Ltd | Information & communication | 2020 |
| Digicomp Solutions Ltd. | Education | 2018 |
| Digital Find Limited | Administrative & support | 2006 |
| Digital Office Automation Limited | Manufacturing | 2014 |
| Digital Plane Group Limited | Information & communication | 2022 |
| Digital UP Consultancy Ltd | Professional & scientific | 2021 |
| Digivizer Limited | Wholesale & retail | 2024 |
| DIL Pro Ltd | Construction | 2019 |
| Dilrio Investments Limited | Real estate | 2018 |
| Dimex Construction Ltd | Construction | 2010 |
| Diomed Developments Limited | Manufacturing | 1963 |
| Diomed Direct Limited | Wholesale & retail | 1997 |
| Diomed Group Holdings Limited | Financial services | 2024 |
| Diomed Limited | Professional & scientific | 2011 |
| Diomed Pharmaceuticals Limited | Professional & scientific | 1998 |
| Dipthy Ltd | Wholesale & retail | 2024 |
| Direct Care and Support Services UK Ltd | Health & social care | 2014 |
| Direct Contact Events Ltd | Administrative & support | 2021 |
| Direct IT Solutions Ltd | Information & communication | 2015 |
| Dirty Harry's Waste Management Ltd | Water & waste | 2008 |
| Discount Cooling Limited | Energy | 2026 |
| Discover Residential Ltd | Households | 2017 |
| Discover Residential Management Ltd | Real estate | 2023 |
| Discovery First Limited | Education | 2016 |
| Diseg Limited | Professional & scientific | 2012 |
| Disruptive Group Distribution Limited | Information & communication | 2018 |
| Disruptive Solutions Distribution Ltd | Information & communication | 2018 |
| Diversity in Recruitment Limited | Professional & scientific | 2021 |
| Divine Coves Limited | Real estate | 2023 |
| Divine Destinations Limited | Administrative & support | 2025 |
| DIY Toolshare Ltd | Administrative & support | 2025 |
| Dizapa Ltd | Information & communication | 2026 |
| Dizzain Ltd | Construction | 2017 |
| DJB Properties Limited | Real estate | 2015 |
| DJE Advisory Services Limited | Administrative & support | 2013 |
| Djem Entertainment Limited | Information & communication | 2006 |
| DJF Site Fixing & Fabrication Limited | Construction | 2014 |
| DJL Plumbing & Heating Limited | Construction | 2023 |
| Djrt Limited | Professional & scientific | 2010 |
| DJS Property Management Ltd | Real estate | 2016 |
| DK Creative Services Ltd | Professional & scientific | 2025 |
| DK Julien Road Limited | Real estate | 2022 |
| DKD Property Holdings Limited | Real estate | 2026 |
| DKH Investments Limited | Construction | 2014 |
| DL Reinforcement Ltd | Construction | 2026 |
| Dmcd Properties Limited | Real estate | 2020 |
| DML Experience Retail Consultancy Ltd | Administrative & support | 2025 |
| Dngu Construction Ltd | Construction | 2026 |
| DNM Commercial Ltd | Construction | 2022 |
| DO Vision-E Limited | Professional & scientific | 2016 |
| Docklands Consultants Ltd | Professional & scientific | 2023 |
| Doctors Relocate Ltd | Administrative & support | 2020 |
| Doctorterry Limited | Health & social care | 2012 |
| Dodope Payments Limited | Administrative & support | 2025 |
| Dolly's Interiors Limited | Manufacturing | 2010 |
| Dominion Earth Ltd | Real estate | 2022 |
| Domus CB2 Developments LLP | | 2014 |
| Domus Homes Limited | Real estate | 2019 |
| Donal Pharm Limited | Health & social care | 2023 |
| Donn Estates Limited | Real estate | 2017 |
| Donor Designated Donations Ltd | Administrative & support | 2019 |
| Doodle Cube Limited | Professional & scientific | 2008 |
| Door Trader Ltd | Extraterritorial | 2014 |
| DOOR25 Marketing Ltd | Professional & scientific | 2025 |
| Dorothyscott Brands Ltd | Wholesale & retail | 2025 |
| Dorset Waste Solutions Limited | Water & waste | 2025 |
| DOS MAS Tacos Ltd | Hospitality | 2021 |
| Dotmasters Limited | Arts & recreation | 2018 |
| Double R Properties Ltd | Real estate | 2024 |
| Dowbiggin Associates Limited | Other services | 2017 |
| Down the Hatch Limited | Hospitality | 2023 |
| Doykov 87 Ltd | Transport & logistics | 2018 |
| Doyle Consultancy Services Ltd | Construction | 2025 |
| DP Interim and Consulting Ltd | Professional & scientific | 2023 |
| DP Investments 1 Limited | Real estate | 2023 |
| DPG Property Developments Ltd | Real estate | 2020 |
| Dplnp Holdings Ltd | Wholesale & retail | 2020 |
| DPS Medical Property Limited | Construction | 2020 |
| DPS Trading Finance Limited | Administrative & support | 2017 |
| DPS Trading Holdings Limited | Construction | 2017 |
| DR Ace Aesthetics Ltd | Health & social care | 2023 |
| DR Hunjan Consultancy Ltd | Health & social care | 2023 |
| DR Leah Baker Street Limited | Other services | 2025 |
| DR Leah Clinics Limited | Other services | 2025 |
| DR Leah Limited | Other services | 2013 |
| DR Leah Loughton Limited | Other services | 2025 |
| DR Leah Moorgate Limited | Other services | 2025 |
| DR Leah Skincare Limited | Wholesale & retail | 2021 |
| DR Nirdosh Limited | Wholesale & retail | 2007 |
| DR Ridez Ltd | Wholesale & retail | 2025 |
| DR Sapna Ltd | Health & social care | 2026 |
| Dragon Wood Homes Ltd | Construction | 2015 |
| Draig Vanguard Ltd | Professional & scientific | 2025 |
| Drainage Consulting Services Limited | Construction | 2014 |
| Drake Media Music Ltd | Information & communication | 2012 |
| Drake Media Properties Ltd | Real estate | 2020 |
| Drayparcs Developments Limited | Construction | 2017 |