| Yellow Spaces Limited | Real estate | 2018 |
| Yellow Tent Business Services Ltd | Professional & scientific | 2022 |
| Yeoman Investments Limited | Real estate | 2017 |
| YES PAL Fitness Ltd | Education | 2022 |
| YES Solutions Ltd | Manufacturing | 2021 |
| Yield Community Limited | Real estate | 2019 |
| Ymsamate Ltd | Wholesale & retail | 2025 |
| Yogibarn Limited | Other services | 2011 |
| Yomoserv Ltd | Professional & scientific | 2024 |
| York Hair Ltd | Other services | 2014 |
| York Metrology Limited | Professional & scientific | 1988 |
| York Recreation Limited | Professional & scientific | 2011 |
| Youmei Food Ltd | Hospitality | 2017 |
| Young Brickwork Services Ltd | Construction | 2018 |
| Young Electrical Contractors Limited | Construction | 2014 |
| Youniverse Digital Limited | Information & communication | 2010 |
| Your Commercial Recruiter Ltd | Administrative & support | 2022 |
| Your Perm Recruiter Ltd | Administrative & support | 2022 |
| Your Recruiters Limited | Administrative & support | 2021 |
| Your Time Psychology Services Ltd | Health & social care | 2022 |
| Your Wheels Ltd | Extraterritorial | 2017 |
| Yourtour Ventures Limited | Information & communication | 2017 |
| Youth Sport Trust | Education | 2001 |
| Youth Sport Trust Enterprises Ltd | Wholesale & retail | 1996 |
| Yttm Ltd | Wholesale & retail | 2019 |
| Yumi Sleep Ltd | Manufacturing | 2024 |
| Yummy 22 Limited | Hospitality | 2021 |
| Z&M Pizza Ltd | Hospitality | 2026 |
| ZAC Bell UK Limited | Wholesale & retail | 2019 |
| Zactiv Glimmer PAD Ltd | Information & communication | 2026 |
| Zactiv Limited | Professional & scientific | 2025 |
| Zahirul Outdoor Catering Limited | Hospitality | 2025 |
| Zaitah Ltd | Wholesale & retail | 2019 |
| Zaitah Properties Ltd | Real estate | 2022 |
| ZAK Properties Letting Limited | Real estate | 2026 |
| Zappo-Now Ltd | Wholesale & retail | 2025 |
| Zayndu Ltd | Professional & scientific | 2019 |
| Zebrand Ltd | Professional & scientific | 2022 |
| Zeddy Productions Limited | Information & communication | 2015 |
| Zeerin Ltd | Hospitality | 2024 |
| Zenntech Ltd | Wholesale & retail | 2025 |
| Zeronicx Ltd | Wholesale & retail | 2025 |
| ZEST4LIFEUK Limited | Arts & recreation | 2012 |
| ZG Entertainment Limited | Arts & recreation | 2024 |
| ZH Grill Limited | Hospitality | 2025 |
| Zhejiang Zhong Ding International Textile Co Ltd | Professional & scientific | 2020 |
| Zimbabwe Doctors Association UK CIC | Education | 2026 |
| Zimyluxehair Limited | Wholesale & retail | 2026 |
| Zinensis Investment Ltd | Real estate | 2023 |
| ZIP Self Store Limited | Extraterritorial | 2008 |
| Zisk Ltd | Administrative & support | 2020 |
| Ziva Global CIC | Health & social care | 2026 |
| Zora Defence Ltd | Administrative & support | 2024 |
| Zouch Islands (Management) Limited | Households | 1990 |
| Zouch Mill Management Company Limited | Real estate | 1999 |
| Zsaura Limited | Wholesale & retail | 2025 |
| Zsnera Ltd | Wholesale & retail | 2025 |
| ZW Autos Ltd | Wholesale & retail | 2022 |
| Zyhm Consulting Ltd | Wholesale & retail | 2018 |
| ZZA Ventures Ltd | Wholesale & retail | 2026 |