| Uni-Goer Ltd | Professional & scientific | 2024 |
| Unidata Solutions Ltd | Information & communication | 2012 |
| Unified Care Services Holdings Ltd | Financial services | 2023 |
| Unified Care Services Ltd | Health & social care | 2023 |
| Unified Care Services Property Management Ltd | Real estate | 2024 |
| Union Wharf Management Company Limited | Households | 1995 |
| Union-Coops:Uk Ltd | Other services | 2021 |
| Uniq Lets Ltd | Real estate | 2021 |
| Unique Finish Limited | Wholesale & retail | 2014 |
| Unite Logistics Ltd | Transport & logistics | 2018 |
| United Care Concepts Limited | Health & social care | 2009 |
| United Kingdom Anti-Doping Limited | Information & communication | 2009 |
| United Kingdom Property Networking Limited | Administrative & support | 2023 |
| United Orthopedics Limited | Wholesale & retail | 2019 |
| United Travel Group Limited | Transport & logistics | 1972 |
| United Travel Holdings Limited | Information & communication | 1996 |
| Unitrove Asset Management Group Limited | Extraterritorial | 2020 |
| Unitrove Asset Management Limited | Administrative & support | 2020 |
| Unitrove Consulting Group Limited | Extraterritorial | 2020 |
| Unitrove Consulting Limited | Professional & scientific | 2020 |
| Unitrove Energy Group Limited | Extraterritorial | 2020 |
| Unitrove Energy Limited | Extraterritorial | 2020 |
| Unitrove Group Limited | Financial services | 2020 |
| Unitrove Innovation Group Limited | Extraterritorial | 2020 |
| Unitrove Innovation Limited | Professional & scientific | 2020 |
| Unitrove Limited | Real estate | 2008 |
| Unitrove Technology Group Limited | Extraterritorial | 2020 |
| Unitrove Technology Limited | Extraterritorial | 2020 |
| Unitt Quorn Limited | Extraterritorial | 2017 |
| Universal Contracting Services LLP | | 2022 |
| Universal Power Systems Limited | Extraterritorial | 2007 |
| Universal Real Estate (PVT) Ltd | Real estate | 2018 |
| Unwantees Limited | Extraterritorial | 1999 |
| UP Start CFO Ltd | Professional & scientific | 2024 |
| Uploader Media Limited | Information & communication | 2019 |
| Upper George Street Ltd | Construction | 2020 |
| Uppercase Media Limited | Information & communication | 2013 |
| Upton Properties Braunston Limited | Real estate | 2016 |
| Uptown Property Developments Ltd | Construction | 2009 |
| Uranus Bubble Tea Limited | Manufacturing | 2022 |
| Uranus Group Purchase Limited | Hospitality | 2024 |
| Uranus Property Limited | Real estate | 2021 |
| Urban Biryani Co UK Ltd | Hospitality | 2026 |
| Urban Grain Developments Ltd | Construction | 2025 |
| Urban Mobility Systems (UK) Limited | Wholesale & retail | 2023 |
| Urban Spud Ltd | Hospitality | 2025 |
| Urgo Limited | Manufacturing | 2001 |
| Urotek Medicare UK Limited | Wholesale & retail | 2018 |
| Ursa Holdings Limited | Financial services | 2025 |
| USE the Muse Limited | Professional & scientific | 2022 |
| Uskfuture Ltd | Information & communication | 2025 |
| Utility Information Services Ltd | Professional & scientific | 2013 |
| Utility Survey Exchange Ltd | Information & communication | 2017 |
| UV Transport Ltd | Other services | 2018 |
| V & S (Weston) Limited | Construction | 2002 |
| V & S Fabrications Limited | Construction | 1988 |
| V&E Delivery Ltd | Transport & logistics | 2019 |
| Vacuum Brazing Consultants Limited | Manufacturing | 1991 |
| Vacuum Brazing Corporation Ltd | Extraterritorial | 2009 |
| Valda & Daughter Ltd | Other services | 2002 |
| Vale Care Limited | Administrative & support | 2017 |
| Valleytake Limited | Professional & scientific | 1988 |
| Valuechain Ventures Ltd | Information & communication | 2020 |
| Van DER Beek-Doornberg Ltd | Arts & recreation | 2016 |
| Vancenco Solutions Ltd | Professional & scientific | 2025 |
| Vanday Ltd | Wholesale & retail | 2025 |
| Vanessa Gregory Property Consultants Limited | Real estate | 2025 |
| Vanilla Copy Ltd | Professional & scientific | 2011 |
| Vanpimps Ltd | Wholesale & retail | 2014 |
| Vansafe UK Ltd | Administrative & support | 2023 |
| Vanst UK Limited | Extraterritorial | 2011 |
| Vantage Energy Management Ltd | Professional & scientific | 2020 |
| Vantage Properties Leicester Ltd | Real estate | 2024 |
| Vantix Cargo Limited | Transport & logistics | 2026 |
| Vape HQ (Loughborough) Limited | Wholesale & retail | 2013 |
| Vault and Vivre Ltd | Wholesale & retail | 2025 |
| Vaultiq Security Ltd | Administrative & support | 2016 |
| Vaults Management Company (Ashby) Limited | Households | 2006 |
| VBC Group Ltd | Financial services | 2009 |
| VCO Bars Ltd | Hospitality | 2025 |
| VCO Merch Ltd | Wholesale & retail | 2021 |
| Vdce Limited | Information & communication | 2024 |
| Vector Technology Ltd | Information & communication | 2026 |
| Vedi Food Ltd | Hospitality | 2019 |
| VEE DUB Transporters Limited | Wholesale & retail | 2012 |
| Veeraaj Ltd | Wholesale & retail | 2026 |
| VEG Trust Incorporating the Matthew Eyton Animal Welfare Trust | Information & communication | 2020 |
| Vegan Campaigns Ltd | Information & communication | 2014 |
| Vehicle Arts Ltd | Arts & recreation | 2019 |
| Velt Limited | Construction | 2015 |
| Velvet Trowel Ltd | Construction | 2024 |
| Venaveer Software Services Limited | Other services | 2012 |
| Ventura Hair Salon Limited | Other services | 2021 |
| Venturewilson Limited | Real estate | 2016 |
| Ventureworkx Limited | Information & communication | 2023 |
| Ventus Enterprises Limited | Professional & scientific | 2005 |
| Verdant Corporation Ltd | Information & communication | 2022 |
| Vero Advisory Partners Ltd | Professional & scientific | 2024 |
| Verse 11 Ltd | Wholesale & retail | 2025 |
| Versha’S Rasoi Ltd | Hospitality | 2025 |