| Elschem Solutions Limited | Professional & scientific | 2022 |
| Elwood Property Limited | Real estate | 2021 |
| Elysian Eco Property Ventures Limited | Real estate | 2024 |
| Elysian Land & Asset Discovery Limited | Real estate | 2025 |
| Elysian Trade Limited | Information & communication | 2025 |
| Elysium Aesthetics Ltd | Health & social care | 2017 |
| Emanagers Limited | Information & communication | 2010 |
| Emanuel Transport Limited | Administrative & support | 2018 |
| Embroidery Expressions (Holdings) Ltd | Financial services | 2015 |
| Embroidery Expressions Limited | Administrative & support | 2002 |
| Emeb Ltd | Construction | 2018 |
| Emergency Plumber Only Advance Plumbing Limited | Manufacturing | 2025 |
| Emily Bentham Hypnotherapy Ltd | Health & social care | 2025 |
| Emmaboda Limited | Real estate | 2022 |
| Emmett Inns Limited | Hospitality | 2018 |
| Emos Courier Ltd | Transport & logistics | 2025 |
| Empire Finance Limited | Financial services | 2013 |
| Empire Group Loughborough Ltd | Hospitality | 2019 |
| Empire Tandoori Ltd | Hospitality | 2022 |
| Empire Wealth Limited | Administrative & support | 2024 |
| Empireset Properties Limited | Real estate | 1999 |
| Emporium Home Cleaning Services Ltd | Other services | 2025 |
| Empower Through Catering CIC | Other services | 2025 |
| Emprop Ltd | Real estate | 2025 |
| EMS Living Ltd | Health & social care | 2026 |
| Emserv Limited | Professional & scientific | 2024 |
| EMT Investments Limited | Real estate | 2024 |
| EMT Legal Limited | Professional & scientific | 2026 |
| ENA Prop Ltd | Construction | 2025 |
| Enabled by RW Ltd | Professional & scientific | 2022 |
| Endeavours Student Adventures Ltd | Administrative & support | 2019 |
| Endless Chances Ltd | Wholesale & retail | 2024 |
| Endorphu Productions Ltd | Information & communication | 2022 |
| Energy Furnishings Ltd | Wholesale & retail | 2022 |
| Enertrix Ltd | Wholesale & retail | 2025 |
| Engage Finance Limited | Financial services | 2018 |
| Engage Property Solutions Ltd | Real estate | 2019 |
| Engenior Consulting Ltd | Professional & scientific | 2024 |
| Engigreening Ltd | Professional & scientific | 2024 |
| Engineered Reinforcing Steel Industries UK Limited | Administrative & support | 2017 |
| Engineering Manufacturing Solutions Ltd | Professional & scientific | 2010 |
| England Futsal Community C.I.C. | Education | 2025 |
| English Federation of Disability Sport | Arts & recreation | 1998 |
| English Federation of Disability Sport Events Management Limited | Arts & recreation | 2006 |
| English Sports Development Trust Limited | Arts & recreation | 2001 |
| English Volleyball Association Limited | Arts & recreation | 1986 |
| Enhance Recruitment Ltd | Administrative & support | 2019 |
| Enkindle Ltd | Professional & scientific | 2025 |
| Enrec Engineering Limited | Professional & scientific | 2012 |
| Ensignia Property Limited | Real estate | 2010 |
| Enterprise CN Limited | Professional & scientific | 2015 |
| Ents Store Ltd | Hospitality | 2023 |
| Envigo Holdings Limited | Administrative & support | 1995 |
| Envigo RMS (UK) Limited | Manufacturing | 1976 |
| Envisage Consulting Ltd | Information & communication | 2008 |
| Envisage Estates Limited | Real estate | 2017 |
| Envisage Global Holdings Limited | Financial services | 2017 |
| Envision Project Limited | Education | 2019 |
| Enxus Limited | Agriculture & fishing | 2023 |
| Enzo Presents Ltd | Arts & recreation | 2025 |
| Enzyme HR Ltd. | Administrative & support | 2013 |
| EOS Design Ltd | Professional & scientific | 2016 |
| Eparking Limited | Transport & logistics | 2022 |
| Epic Coffee Limited | Hospitality | 2025 |
| Epinal Way Care Limited | Health & social care | 2021 |
| Eploy Limited | Information & communication | 2005 |
| Epos Data Solutions Limited | Information & communication | 2013 |
| Epracing Ltd | Wholesale & retail | 2007 |
| EPS UK Holdings Limited | Financial services | 2018 |
| Equate Digital Limited | Information & communication | 2021 |
| Equilibrium Skin & Laser Clinic Limited | Other services | 2019 |
| Equinox Search Limited | Real estate | 2024 |
| EQUINOX24 Limited | Arts & recreation | 2014 |
| Erebus Advisors Limited | Financial services | 2022 |
| Erick's Developments Ltd | Construction | 2026 |
| Eros Chatting Limited | Wholesale & retail | 2024 |
| ERS (East Midlands) Ltd | Manufacturing | 2022 |
| ESC Homes Limited | Real estate | 2018 |
| Escapade Retail Solutions Limited | Wholesale & retail | 2004 |
| Esendee Holdings Limited | Financial services | 2011 |
| Esgard Limited | Information & communication | 2026 |
| Eshfa Trading Ltd | Wholesale & retail | 2021 |
| Esperanza Food Limited | Hospitality | 2023 |
| Essex Abel Limited | Professional & scientific | 2000 |
| Essex Property Investment Collective Ltd | Real estate | 2025 |
| Estia Estates Ltd | Real estate | 2024 |
| Etech Digital Solutions Ltd | Wholesale & retail | 2025 |
| Eternal Embroidery Limited | Arts & recreation | 2015 |
| Eternatree Ltd | Other services | 2025 |
| Eternity SEO Limited | Professional & scientific | 2024 |
| Eteronix Limited | Wholesale & retail | 2025 |
| Ethical Festival Ltd | Arts & recreation | 2013 |
| Ethnic Bar Ltd | Hospitality | 2023 |
| Ethos One Limited | Information & communication | 2023 |
| Euphrenity Ltd | Professional & scientific | 2021 |
| Eureka Innovative Solutions Limited | Wholesale & retail | 2008 |
| Euro Asia Cash & Carry Ltd | Hospitality | 2014 |
| Euro Filter Installations Limited | Professional & scientific | 2006 |
| Euro Store Loughborough Ltd | Wholesale & retail | 2024 |
| Eurofilter Limited | Extraterritorial | 2015 |