| Edugate AI Solutions Ltd | Information & communication | 2025 |
| Edutestpro Ltd | Information & communication | 2026 |
| EF Mccambridge & Co. Ltd | Professional & scientific | 2018 |
| Effix Limited | Professional & scientific | 2024 |
| Efni Ltd | Financial services | 2013 |
| Eglinton Developments Limited | Construction | 2015 |
| Eglinton Kayaks Ltd | Wholesale & retail | 2021 |
| EH Recovery Ltd | Other services | 2025 |
| EHG Events Ltd | Arts & recreation | 2024 |
| EI Takeaway Foods Ltd | Hospitality | 2024 |
| EJA Investments Ltd | Administrative & support | 2019 |
| EJS Contracts Limited | Real estate | 2018 |
| EKO Hoofcare Limited | Agriculture & fishing | 2015 |
| EKT Global Sourcing Ltd | Wholesale & retail | 2026 |
| EL Phinia Ltd | Real estate | 2018 |
| EL Tapas GRA Ltd | Hospitality | 2026 |
| Elagh Property Limited | Households | 2021 |
| Elagh Tree Surgery Limited | Agriculture & fishing | 2015 |
| Elaine Mclaughlin Limited | Professional & scientific | 2013 |
| Electrical Control and Instrument Services Limited | Professional & scientific | 1995 |
| ELEV8 Living Ltd | Real estate | 2026 |
| Elevate (Foyle) Ltd | Other services | 2023 |
| Elgloree Limited | Health & social care | 2024 |
| Elgloree Properties Limited | Real estate | 2026 |
| Elite Holdings (N.I.) Ltd | Wholesale & retail | 2018 |
| Elite Mindset Academy Ltd | Professional & scientific | 2021 |
| Elite Networks NI Limited | Construction | 2021 |
| Elite Security TM Ltd | Administrative & support | 2021 |
| ELM Village Company Limited | Real estate | 2015 |
| Elmoreton Limited | Hospitality | 1993 |
| EM Motion Limited | Information & communication | 2019 |
| EM Podiatry Ltd | Public administration | 2021 |
| Embassy Property Limited | Real estate | 2017 |
| EMC Drylining Ltd | Construction | 2018 |
| Emclaughlin Ltd | Professional & scientific | 2020 |
| EMD Boiler Repair & Maintenance Limited | Other services | 2023 |
| EMD Boiler Services Ltd | Construction | 2021 |
| EMD Plumbing Heating Ltd | Construction | 2026 |
| Emerald Medical Limited | Manufacturing | 2026 |
| Emerald Palace Food Ltd | Hospitality | 2025 |
| Emerald Pulse Entertainment Ltd | Administrative & support | 2025 |
| Emerald Wealth Limited | Professional & scientific | 2025 |
| Emergency AID Supplies Limited | Wholesale & retail | 1996 |
| EMG Construction Ltd | Construction | 2018 |
| EMK Consulting Engineers Ltd | Construction | 2020 |
| Emmett Brolly Electrical Limited | Construction | 2025 |
| Emoc Properties Ltd | Real estate | 2009 |
| Empmproperties Ltd | Real estate | 2022 |
| ENA Electrics Ltd | Construction | 2024 |
| Enagh Country Park Enterprises Ltd | Other services | 2019 |
| Enapa Ltd | Professional & scientific | 2024 |
| Enfa Holdings Ltd | Real estate | 2025 |
| Engine House Interactive Limited | Arts & recreation | 2025 |
| Engineering Maintenance and Fitting Ltd | Professional & scientific | 2024 |
| Enigma UH Ltd | Real estate | 2018 |
| Enkalon Developments Limited | Real estate | 2023 |
| Enkalon Enterprises Limited | Manufacturing | 2020 |
| Ensul Limited | Professional & scientific | 2013 |
| Enterprise House Limited | Real estate | 1999 |
| Entertainment Ideas Online Limited | Other services | 2012 |
| Enviro Car Parts Limited | Manufacturing | 2013 |
| Envirocarpartsonline Limited | Wholesale & retail | 2025 |
| Environmental Aerosols Ltd | Professional & scientific | 2024 |
| EOK Drylining Ltd | Construction | 2025 |
| Eolas Inniu Ltd | Real estate | 2020 |
| ERE LPS Holdings Ltd | Financial services | 2013 |
| Eremon Pneus Ltd | Wholesale & retail | 2016 |
| Erin C Smith Designs Ltd | Professional & scientific | 2025 |
| Erne Developments Limited | Real estate | 2004 |
| Erne Limited | Real estate | 2016 |
| Errigal Homes Limited | Construction | 2022 |
| Errigal Interiors (NI) Limited | Other services | 2015 |
| Errigal IWI (Holdings) Limited | Construction | 2023 |
| Errigal Motors NW Limited | Wholesale & retail | 2019 |
| Ervey Holdings Limited | Financial services | 2024 |
| Esbni Limited | Energy | 2010 |
| Escee Ltd | Wholesale & retail | 2021 |
| Eskimo Coffee Company Limited | Hospitality | 2016 |
| Espressgo Ltd | Wholesale & retail | 2023 |
| Esquire Suit Sale & Hire Limited | Wholesale & retail | 2016 |
| ET & T Services Limited | Construction | 2024 |
| European Coaching Academy Ltd | Professional & scientific | 2022 |
| European Work Administration Ltd | Administrative & support | 2024 |
| Ev-Collective Ltd | Professional & scientific | 2014 |
| Evander (NI) Limited | Construction | 2014 |
| Evergriin European Ltd | Financial services | 2022 |
| Evergriin Ltd | Financial services | 2025 |
| Evernu Ltd | Health & social care | 2025 |
| Evide Impact Limited | Information & communication | 2018 |
| Excellence Through Exercise & Learning (Excel) C.I.C. | Education | 2021 |
| Exchange Restaurants Limited | Hospitality | 2005 |
| Exclusive Doors & Floors Ltd | Wholesale & retail | 2019 |
| Exclusive Fit-Out Bespoke Joinery and Fitting Ltd | Construction | 2024 |
| Executive Studio 4D Limited | Professional & scientific | 2008 |
| Express Foodservice (NI) Limited | Wholesale & retail | 2011 |
| Extenso Developments Ltd | Professional & scientific | 2025 |
| Eyespyfx Limited | Information & communication | 2001 |
| EZ Steps Ltd | Wholesale & retail | 2025 |
| Facing Young Ltd | Wholesale & retail | 2024 |
| Fairley's Flavours Ltd | Manufacturing | 2020 |