| A J Pipeline (Anglesey) Limited | Construction | 2013 |
| A&S Engineering and Repairs Ltd | Professional & scientific | 2025 |
| A.C. Roof Trusses Limited | Extraterritorial | 2003 |
| A.R. Hendricks Limited | Extraterritorial | 1987 |
| AG Gatehouse Ltd | Extraterritorial | 2024 |
| AGE Well Hwyliog MON | Other services | 2013 |
| Alpemir Ltd | Hospitality | 2025 |
| Always AIM High Community Events Limited | Arts & recreation | 2015 |
| Alwyn Frazer Plastering Contractor Ltd | Construction | 2024 |
| Anglesey Apparel MON Ltd | Wholesale & retail | 2022 |
| Anglesey Direct Cremations Ltd | Other services | 2025 |
| Anglesey Heating & Plumbing Services Ltd. | Construction | 1997 |
| Anglesey Hideaways Ltd | Hospitality | 2021 |
| Anglesey Holiday Lettings Limited | Hospitality | 2020 |
| Anglesey Mobility Ltd | Wholesale & retail | 2014 |
| Anglesey Power Solutions Engineering Limited | Information & communication | 2022 |
| Anglesey Solar & Electrical Ltd | Construction | 2021 |
| Annog CYF | Professional & scientific | 1999 |
| AP Thomas CYF | Professional & scientific | 2014 |
| Arda ODS Ltd | Hospitality | 2024 |
| Arwel Humphreys CYF | Manufacturing | 2014 |
| B & M Farming Ltd | Agriculture & fishing | 2022 |
| Barnfit Ltd | Arts & recreation | 2025 |
| Bastion Tabletop Limited | Administrative & support | 2017 |
| Bathroom Distribution Group UK Limited | Wholesale & retail | 1978 |
| Bella Food Llangefni Ltd | Hospitality | 2025 |
| Blhp Group Ltd | Administrative & support | 2023 |
| BTJ Enterprises Ltd | Administrative & support | 2003 |
| Builders Supplies (West Coast) Limited | Extraterritorial | 1956 |
| Building Supplies Distribution Limited | Extraterritorial | 2003 |
| Bwyd DA MON CBC | Other services | 2020 |
| Bythynnod Bryn Gwallen CYF | Hospitality | 2018 |
| C1PHERTECH Limited | Other services | 2016 |
| Cadarn Consulting Engineers Limited | Professional & scientific | 2013 |
| CAI Data Ltd | Professional & scientific | 2024 |
| Canolfan Glanhwfa CYF | Education | 2013 |
| Cefn Cwmwd Cottages Limited | Hospitality | 1997 |
| Cefn Cwmwd Cottages Management Company Limited | Administrative & support | 2021 |
| Cefni Garage Ltd | Manufacturing | 2015 |
| Celt Scaffolding Ltd | Construction | 2024 |
| Chilli Spice 36 Limited | Hospitality | 2025 |
| Clinic Ceiropracteg Ltd. | Health & social care | 2019 |
| Clinig Laser MÔN CYF | Health & social care | 2025 |
| Clwb Rygbi Llangefni CYF | Arts & recreation | 2015 |
| Concept Spa Ltd | Wholesale & retail | 2015 |
| Countrywide Contract Flooring Ltd. | Construction | 2009 |
| Craig Pugh Construction Ltd | Construction | 2021 |
| Crescent Building Supplies (Ruislip) Limited | Extraterritorial | 2003 |
| Cubs Play Centre Bangor Ltd | Hospitality | 2026 |
| Cubs Play Centre Ltd | Hospitality | 2025 |
| Curtis Painting Group Ltd | Construction | 2003 |
| Cwmni KEV Bach Ltd | Information & communication | 2021 |
| D C Williams & SON Ltd | Wholesale & retail | 2020 |
| Dafydd Hughes & Co Ltd | Professional & scientific | 2017 |
| Danielcare Limited | Health & social care | 2022 |
| Deni Kiro Style Limited | Other services | 2021 |
| Dinorwic Services Ltd | Administrative & support | 2011 |
| DP Heating Solutions Ltd | Construction | 2021 |
| Dragon Garage Doors Ltd | Manufacturing | 2015 |
| Dylan Jones & Sons Ltd | Construction | 2019 |
| Dylan's Group Ltd | Financial services | 2024 |
| Dylan's Restaurant Holdings Ltd | Real estate | 2024 |
| Dylan's Restaurant Ltd | Hospitality | 2012 |
| E J Roberts Consultancy CYF | Professional & scientific | 2026 |
| Eco Earth Apparel Ltd | Wholesale & retail | 2016 |
| Eira Therapy Ltd | Wholesale & retail | 2023 |
| Elite Changeovers Limited | Administrative & support | 2022 |
| Enterprise Telecoms Ltd | Information & communication | 2014 |
| Exall Jones Limited | Extraterritorial | 1983 |
| Exchange Properties NW Ltd | Real estate | 2022 |
| Faizalnazim & Associate Limited | Information & communication | 2012 |
| FAN Duoduo Limited | Hospitality | 2026 |
| Fast JET Performance Ltd | Professional & scientific | 2017 |
| Faun Trackway Limited | Manufacturing | 2014 |
| Fferam Bailey Ltd | Agriculture & fishing | 2020 |
| Ffitrwydd MON Fitness Gym Ltd | Arts & recreation | 2025 |
| Ffitrwydd MON Fitness Studio Ltd | Arts & recreation | 2025 |
| First Independent Commerce of North Wales Limited | Administrative & support | 1996 |
| Flynn Occupational Therapy Ltd | Health & social care | 2024 |
| Fowler & Hare (Anglesey) Limited | Real estate | 1979 |
| Fowler & Hare (Porthmadog) Limited | Professional & scientific | 1981 |
| Fron Consulting Ltd | Professional & scientific | 2025 |
| Frontline Bathrooms Ltd. | Wholesale & retail | 1990 |
| G and H Services NW Limited | Professional & scientific | 2012 |
| Geomon-Anglesey Geopark Ltd | Education | 2008 |
| Glanaber Holdings Ltd | Financial services | 2025 |
| Glynllifon Holdings Ltd | Financial services | 2024 |
| Glynllifon Ltd | Construction | 2019 |
| Glynllifon Management Ltd | Real estate | 2023 |
| Gmac OPS Ltd | Professional & scientific | 2015 |
| Gofal Seibiant Care Limited | Health & social care | 2014 |
| Good Life Therapies Ltd. | Wholesale & retail | 2017 |
| Grandmere Limited | Hospitality | 1981 |
| Gwneud Make DO C.I.C. | Arts & recreation | 2023 |
| Gwy-Môn Media Ltd | Information & communication | 2024 |
| Gwynedd Sandblasting Ltd | Construction | 2011 |
| Hair by Hamilton Ltd | Other services | 2021 |
| Harvey Steel Lintels Limited | Manufacturing | 1992 |
| Hendre Milk Limited | Agriculture & fishing | 2022 |
| HIB - Exhausts Limited | Manufacturing | 2008 |