| SPT Management Ltd | Professional & scientific | 2023 |
| SR Elite Limited | Wholesale & retail | 2026 |
| SR Horizons Limited | Wholesale & retail | 2025 |
| SR Investment Group Ltd | Wholesale & retail | 2025 |
| SRI KKI Ltd | Real estate | 2019 |
| SS Services & Retail Ltd | Wholesale & retail | 2024 |
| SSP Infotech Limited | Information & communication | 2019 |
| Ssrm Ltd | Information & communication | 2024 |
| SST Systems Limited | Administrative & support | 2017 |
| Stafford VS Holdings Limited | Hospitality | 2026 |
| Stairwell Cleaning Services Limited | Water & waste | 2022 |
| Stange Kraft Ltd | Manufacturing | 2011 |
| Stanz Property Ltd | Real estate | 2023 |
| Star Leisure Products Limited | Manufacturing | 2025 |
| Starlaw Management Limited | Extraterritorial | 2012 |
| STC Clark Ltd | Construction | 2026 |
| Steadfast Global Ltd | Manufacturing | 2023 |
| Steve Marsden Fitness Ltd | Arts & recreation | 2019 |
| Stevenson Care Limited | Health & social care | 2020 |
| Stewart Kyle & Co Ltd | Other services | 2023 |
| Stewarton Farms Ltd | Agriculture & fishing | 2019 |
| Still Hearing Limited | Health & social care | 2025 |
| Stipis General Partner | Financial services | 2011 |
| Stipis Properties Ltd | Households | 2022 |
| Stirlingshire Lawncare Services Ltd | Administrative & support | 2023 |
| Stitt Ltd | Real estate | 2017 |
| Stokes Michael SAM Ltd | Wholesale & retail | 2026 |
| Stonecliff Holdings Limited | Real estate | 2026 |
| Stone’S Kitchen Co. Ltd | Hospitality | 2022 |
| Storedge Limited | Transport & logistics | 2015 |
| Strada Private Hire Ltd | Transport & logistics | 2024 |
| Strathblair Consulting Limited | Professional & scientific | 2013 |
| Stream Consultancy Limited | Information & communication | 2026 |
| Stream Digital Ltd | Information & communication | 2019 |
| Street Cabs Ltd | Transport & logistics | 2026 |
| Streetlane Media Ltd | Information & communication | 2018 |
| Strong Tower Investment Ltd | Construction | 2021 |
| Structured Events Ltd | Administrative & support | 2024 |
| STRUX1 Ltd | Construction | 2026 |
| STS Fitout Ltd | Construction | 2017 |
| Stuart's Letting & Management Ltd | Real estate | 1999 |
| Studio Carpentry LLP | | 2013 |
| Studio East Edinburgh Limited | Other services | 2020 |
| Studio Lingua Ltd | Information & communication | 2025 |
| Stylehorizon Ltd | Wholesale & retail | 2024 |
| Stylerite Limited | Wholesale & retail | 2014 |
| SUB Zero Ecoblasting Ltd | Transport & logistics | 2025 |
| Subcold Ltd | Wholesale & retail | 2014 |
| Sudan PH Ltd | Transport & logistics | 2026 |
| Sugar Rush by Aiza Limited | Wholesale & retail | 2024 |
| Sundial Dundas (Corstorphine) Limited | Administrative & support | 2017 |
| Superfare Ltd | Wholesale & retail | 2008 |
| Superior Renovations Ltd | Construction | 2013 |
| Supernova Studios Ltd | Other services | 2026 |
| Supersets Tennis Athlete Performance Limited | Education | 2026 |
| Supperbowl Bankton Ltd | Hospitality | 2018 |
| Surface Experts Ltd | Construction | 2024 |
| Surveys and Certificates Ltd | Other services | 2019 |
| Sustainable Sport (Scotland) Ltd | Professional & scientific | 2024 |
| Sutherland Holdings UK Ltd | Real estate | 2020 |
| SVJ Smile Hub Ltd | Health & social care | 2023 |
| Swan Sea Investment | | 2007 |
| SWANS321 Ltd | Hospitality | 2026 |
| Sweet Inspiration Decorators Ltd | Construction | 2023 |
| Sweet Service UK Ltd | Hospitality | 2020 |
| Swift Corporation Limited | Wholesale & retail | 1987 |
| Swiftshopuk Ltd | Wholesale & retail | 2026 |
| Swifttouche Technologies Limited | Information & communication | 2014 |
| Swilcan Financial Partners Limited | Professional & scientific | 2021 |
| Swilcan Wealth Limited | Professional & scientific | 2018 |
| Sykam Solutions Limited | Wholesale & retail | 2003 |
| Synergy Link (UK) Limited | Professional & scientific | 2016 |
| T Cuts Craigshill Ltd | Other services | 2025 |
| T.A.V.E. Beulah Services Ltd | Health & social care | 2014 |
| T1 Foods Scotland Ltd | Hospitality | 2025 |
| T4M Engineering Ltd | Construction | 2018 |
| Tadanai Limited | Transport & logistics | 2023 |
| TAG Building Developments Limited | Construction | 2022 |
| Taggs Ltd | Transport & logistics | 2025 |
| Tajspices Wholesale Limited | Wholesale & retail | 2020 |
| Takc Property Ltd | Real estate | 2026 |
| Takcs Limited | Transport & logistics | 2024 |
| Takumi Vanguard Ltd | Wholesale & retail | 2025 |
| Talisman Taxis Ltd. | Professional & scientific | 2002 |
| Talkingboy Ltd | Wholesale & retail | 2025 |
| TAM Richardson Ltd | Professional & scientific | 2012 |
| Tanisha Homes Ltd | Real estate | 2021 |
| Tantallon Technical Limited | Professional & scientific | 2025 |
| TAR Enterprising Limited | Wholesale & retail | 2023 |
| Target Veterinary Services Limited | Professional & scientific | 2017 |
| Target-Fm Limited | Administrative & support | 2020 |
| Targeted Software Solutions Limited | Information & communication | 1999 |
| Targgs Limited | Transport & logistics | 2025 |
| Tartan Bridge Films Scotland Ltd | Information & communication | 2025 |
| Tartan Golf International Limited | Other services | 1984 |
| Tartan Tackle Ltd | Information & communication | 2026 |
| Taskgroup Automotive Limited | Wholesale & retail | 2022 |
| Taste Culture Ltd | Hospitality | 2025 |
| Taudler Limited | Wholesale & retail | 2023 |
| Taxi Near ME Ltd | Transport & logistics | 2021 |