| Seema HRP Worldwide Ltd | Wholesale & retail | 2024 |
| Seema Property Investments Ltd | Real estate | 2024 |
| Seena Studios Limited | Arts & recreation | 2026 |
| Seeux Champions Academy Ltd | Arts & recreation | 2025 |
| Seeyououtofcourt.Com Ltd | Professional & scientific | 2019 |
| SEF Consultancy Ltd | Professional & scientific | 2025 |
| Sefton & Formby Construction Limited | Construction | 2024 |
| Sefton & Formby Holdings Limited | Financial services | 2024 |
| Sefton and Formby Developments Limited | Real estate | 2023 |
| Sefton Car & Commercial Repairs Ltd | Wholesale & retail | 2023 |
| Sefton Car Wash Limited | Other services | 2026 |
| Sefton Carers Centre | Health & social care | 1995 |
| Sefton Classics Ltd | Extraterritorial | 2017 |
| Sefton Council for Voluntary Service | Health & social care | 1993 |
| Sefton Developments Ltd | Construction | 2023 |
| Sefton Electrical Services Ltd | Construction | 2003 |
| Sefton Estates (Liverpool) Ltd | Real estate | 2017 |
| Sefton Hire Limited | Wholesale & retail | 2007 |
| Sefton Hospitality Limited | Hospitality | 2016 |
| Sefton Hospitality Operations Ltd | Hospitality | 2021 |
| Sefton Integration Limited | Professional & scientific | 2011 |
| Sefton Logistics Co Limited | Transport & logistics | 1998 |
| Sefton Markets Limited | Wholesale & retail | 2016 |
| Sefton Meadows Limited | Wholesale & retail | 2001 |
| Sefton Multicultural Centre | Education | 2019 |
| Sefton New Developments Ltd | Construction | 2023 |
| Sefton Padel Limited | Arts & recreation | 2025 |
| Sefton Park Business Ltd | Administrative & support | 2019 |
| Sefton Park Maintenance Ltd | Real estate | 2015 |
| Sefton Park Management Limited | Administrative & support | 2017 |
| Sefton Park Suites Ltd | Hospitality | 2026 |
| Sefton Plumbing Services Ltd | Construction | 2023 |
| Sefton Podiatry Limited | Health & social care | 2025 |
| Sefton Properties Limited | Real estate | 2003 |
| Sefton Property Holdings Ltd | Wholesale & retail | 2019 |
| Sefton Property Limited | Real estate | 2014 |
| Sefton Rugby Union Football Club | Arts & recreation | 2012 |
| Sefton Security Services Limited | Construction | 2018 |
| Sefton Solar Limited | Construction | 2023 |
| Sefton Springers Trampolining Club C.I.C. | Education | 2026 |
| Sefton Stars Basketball Club | Arts & recreation | 2012 |
| Sefton Street Car Wash Liverpool Ltd | Other services | 2024 |
| Sefton Street DRY Cleaners Limited | Other services | 2026 |
| Sefton Street Services Ltd | Wholesale & retail | 2025 |
| Sefton Tank Services Ltd | Administrative & support | 2025 |
| Sefton Thrive Education & Wellbeing Ltd | Education | 2025 |
| Sefton Towers Ltd | Real estate | 2026 |
| Sefton Training and Enterprise Projects Limited | Hospitality | 2006 |
| Sefton Upvc Ltd | Construction | 2011 |
| Sefton Waste Management Limited | Water & waste | 2024 |
| Sefton Window Cleaning Services Ltd | Administrative & support | 2020 |
| SEG Management Ltd | Administrative & support | 2025 |
| Sehgal Consulting Ltd | Other services | 2025 |
| SEIHIN247 Ltd | Wholesale & retail | 2025 |
| Seis Match Limited | Information & communication | 2012 |
| SEJ Building Services Ltd | Professional & scientific | 2022 |
| Seja Property Limited | Real estate | 2023 |
| Sekander Housing Limited | Real estate | 2005 |
| Sela Construction Limited | Manufacturing | 2017 |
| Selador Recordings Ltd. | Manufacturing | 2013 |
| Selam Capital Ltd | Real estate | 2026 |
| Selasec Limited | Information & communication | 2025 |
| Select Air Services Limited | Energy | 2003 |
| Select Business Group LLP | | 2020 |
| Select Business Services Limited | Information & communication | 2002 |
| Select Car Hire Ltd | Transport & logistics | 2026 |
| Select Carpets Limited | Wholesale & retail | 2021 |
| Select Catering (Huyton) Ltd | Hospitality | 2023 |
| Select Commercial (NW) Limited | Real estate | 2013 |
| Select Digital Business Ltd | Wholesale & retail | 2026 |
| Select Home Care Services Ltd | Health & social care | 2024 |
| Select Offshore Services Limited | Construction | 2018 |
| Select Renewables Ltd | Construction | 2014 |
| Select Roofing & Damp Services Limited | Construction | 2022 |
| Select Sandwich Bar Huyton Ltd | Hospitality | 2019 |
| Select Scaffolds Ltd | Administrative & support | 2006 |
| Select Settles Ltd | Administrative & support | 2018 |
| Select Site Management Ltd | Construction | 2025 |
| Select Training CIC | Education | 2023 |
| Select Upvc Ltd | Manufacturing | 2014 |
| Select Watson LLP | | 2013 |
| Selective Education Services Ltd | Education | 2012 |
| Selector Gearbox Centre Limited | Wholesale & retail | 1987 |
| Selector Holdings Limited | Other services | 2024 |
| Selectrical (Bangor) Limited | Construction | 2009 |
| Selectzone Limited | Wholesale & retail | 2000 |
| Selena Delivery Ltd | Transport & logistics | 2020 |
| Selene Project Management Ltd | Professional & scientific | 2022 |
| Self Agency and Consulting Services Limited | Professional & scientific | 2024 |
| Self Discovery Space Ltd | Other services | 2023 |
| Self Made Community Interest Company | Education | 2025 |
| Self Pick Properties Ltd | Real estate | 2025 |
| Self Same Limited | Wholesale & retail | 2016 |
| Selfish Estelle Ltd | Wholesale & retail | 2025 |
| Selflessly Selfish Ltd | Health & social care | 2026 |
| Selhurst Capital Limited | Administrative & support | 2017 |
| Selienna Properties Ltd | Real estate | 2025 |
| Selinas Investments Limited | Real estate | 2020 |
| Sell My Car Today.Com Ltd | Wholesale & retail | 2025 |
| Sellbuyuk Ltd | Wholesale & retail | 2026 |