| Refine Spray Ltd | Construction | 2025 |
| Refined ( Liverpool) Limited | Other services | 2021 |
| Refinegroup Ltd. | Construction | 2016 |
| Refittr Ltd | Information & communication | 2026 |
| Reflect Evolve Perform Limited | Professional & scientific | 2020 |
| Reflect Facade Solutions Ltd | Construction | 2023 |
| Reflections Training Consultancy Limited | Education | 2012 |
| Reflex Blue Property Limited | Real estate | 2018 |
| Refold Therapeutics Limited | Professional & scientific | 2024 |
| Reform Physiotherapy Clinic Limited | Other services | 2019 |
| Reformat Wellness Ltd | Health & social care | 2025 |
| Reformer Soul Limited | Education | 2023 |
| Reformer YOU Pilates Limited | Arts & recreation | 2025 |
| Reformme Formby Limited | Education | 2023 |
| Refrigerant Sales Ltd | Wholesale & retail | 2014 |
| Refuge Nominees Limited | Financial services | 1980 |
| Refuge Solutions Limited | Information & communication | 2012 |
| Refugee Asylum Design (RAD) CIC | Education | 2024 |
| Refurb Builders Ltd | Real estate | 2026 |
| Reg's Removals Ltd | Transport & logistics | 2024 |
| Regal Entertainments Holdings Limited | Financial services | 2024 |
| Regal Entertainments Limited | Administrative & support | 1999 |
| Regal Land Holdings Ltd | Real estate | 2026 |
| Regal Luxe Ltd | Wholesale & retail | 2024 |
| Regal Shine Auto Care Ltd | Wholesale & retail | 2026 |
| Regal Works Ltd | Construction | 2020 |
| Regalis Consultancy Limited | Professional & scientific | 2026 |
| Regelo Energy Ltd | Professional & scientific | 2025 |
| Regency Court Developments Ltd | Real estate | 2017 |
| Regency Court Management (Liverpool) Ltd | Households | 2018 |
| Regency Group Ltd | Wholesale & retail | 2020 |
| Regency Hotel Group Limited | Hospitality | 2020 |
| Regency Property Asset Management Limited | Real estate | 2008 |
| Regenda Developments Limited | Construction | 1998 |
| Regenerate (NW) Ltd | Real estate | 2020 |
| Regenerate North West Ltd | Real estate | 2022 |
| Regeneration Management Ltd | Construction | 2019 |
| Regenic Homes Limited | Construction | 2024 |
| Regent (North West) Limited | Transport & logistics | 2012 |
| Regent 88 Limited | Hospitality | 2018 |
| Regent Cafe Liverpool Ltd | Hospitality | 2019 |
| Regent Chinese Restaurant Ltd | Hospitality | 2019 |
| Regent Gardens (Bootle) Management Company Limited | Households | 1994 |
| Regent News Ltd | Wholesale & retail | 2025 |
| Regent Road Staycation Ltd | Hospitality | 2025 |
| Regent Systems DEV Ltd | Information & communication | 2025 |
| Regents Plaza C308 Limited | Real estate | 2024 |
| Regiant Holdings Ltd | Financial services | 2024 |
| Regig International Limited | Information & communication | 2024 |
| Regimmas Services & Co Ltd | Health & social care | 2025 |
| Reginald Edward Ltd | Health & social care | 2006 |
| Regional Decorators Ltd | Administrative & support | 2010 |
| Rehab and Wellness Ltd | Health & social care | 2023 |
| Rehab in Progress Limited | Transport & logistics | 2022 |
| Rehders Properties Ltd | Real estate | 2024 |
| Rehoboth International Foods and Beverages Ltd | Wholesale & retail | 2024 |
| Rehoboth UK Limited | Wholesale & retail | 2008 |
| REI REI: BE the Future Ltd | Manufacturing | 2021 |
| Reid Accountancy Ltd | Professional & scientific | 2026 |
| Reid Brothers Haulage Ltd | Transport & logistics | 2024 |
| Reid Plumbing & Heating Ltd | Construction | 2020 |
| Reid's Removal's Ltd | Water & waste | 2025 |
| Reidmark Limited | Information & communication | 1987 |
| Reidmark Properties Limited | Real estate | 2018 |
| Reids Recycling and Investors Ltd | Real estate | 2020 |
| REIGNITE365 Community Sports CIC | Education | 2025 |
| REIGNITE365 Limited | Education | 2025 |
| Reilly Classic Car Company Ltd | Wholesale & retail | 2026 |
| Reilly Legal Consultancy Limited | Professional & scientific | 2015 |
| REJUVEN8 KOKOR0 CIC | Health & social care | 2022 |
| Rejuvenate by Jackie Limited | Other services | 2024 |
| Rejuvenate Services Limited | Construction | 2018 |
| Rejuvenate Wellbeing CIC | Health & social care | 2018 |
| Rejuvenating Skin Ltd | Other services | 2026 |
| Rejuvenation-Rhian Limited | Other services | 2017 |
| Related Construction & Development Ltd | Construction | 2022 |
| Relaxed Business Networking Limited | Other services | 2024 |
| Relaxinn Limited | Real estate | 2020 |
| Relay Agents Limited | Professional & scientific | 2025 |
| Relead Limited | Wholesale & retail | 2018 |
| Relevant Studios Ltd | Arts & recreation | 2023 |
| Reliable Building & Maintenance Ltd | Construction | 2025 |
| Reliable Cargo Transport Ltd | Transport & logistics | 2024 |
| Reliable Handyman Services Ltd | Administrative & support | 2017 |
| Reliable Products Limited | Wholesale & retail | 2025 |
| Reliable Removals Kirkby Ltd | Water & waste | 2020 |
| Reliable Scaffolding Kirkby Limited | Construction | 2022 |
| Reliable Transporter Limited | Transport & logistics | 2014 |
| Reliance Catering Ltd | Hospitality | 2024 |
| Reliant Energy Services Ltd. | Construction | 2013 |
| Religious Life Safeguarding Service Ltd | Professional & scientific | 2021 |
| Relish Restaurants Ltd | Hospitality | 2020 |
| Relismart Safety Ltd | Professional & scientific | 2025 |
| Reliv Ltd | Wholesale & retail | 2025 |
| Relo Consulting Limited | Information & communication | 2014 |
| Relson Trade Limited | Transport & logistics | 2025 |
| REM Property Limited | Real estate | 2019 |
| Remake Liverpool Ltd | Manufacturing | 2012 |
| Remal Thermal Cycling Limited | Manufacturing | 1981 |
| Remarkable Resilience Ltd | Administrative & support | 2025 |