| Drill Surgeries Ltd. | Manufacturing | 2019 |
| Drinkme Ltd | Other services | 2019 |
| Dripin Ltd | Other services | 2022 |
| Drippinglow Ltd | Other services | 2023 |
| Dripunion Limited | Wholesale & retail | 2021 |
| Driscoll CME Limited | Construction | 2021 |
| Driscoll Group Limited | Financial services | 2021 |
| Driscoll Kingston & Co Ltd | Professional & scientific | 2022 |
| Driscoll Kingston Solicitors Limited | Professional & scientific | 2018 |
| Drithii Dhruv Imports and Exports Limited | Wholesale & retail | 2025 |
| Drivanta Group Ltd | Wholesale & retail | 2026 |
| Drive in Storage Limited | Real estate | 2020 |
| Drive Team (North West) Ltd | Construction | 2021 |
| Drive-Well Automotive Ltd | Wholesale & retail | 2025 |
| Driven Care Limited | Public administration | 2022 |
| Driven to Obsession Ltd | Professional & scientific | 2013 |
| Drivenorth Academy Ltd | Administrative & support | 2025 |
| Drivers of Prestatyn Limited | Wholesale & retail | 1986 |
| Driversity Ltd | Education | 2024 |
| Driving Neuron Two Ltd | Financial services | 2025 |
| DRIVING4 Ltd | Transport & logistics | 2026 |
| Drizzle Valets Ltd | Wholesale & retail | 2025 |
| DRJ 1 Trading Limited | Professional & scientific | 2017 |
| DRJ 2 Trading Limited | Professional & scientific | 2017 |
| DRJ 3 Trading Limited | Professional & scientific | 2017 |
| DRJ 4 Trading Limited | Professional & scientific | 2017 |
| DRJ Liverpool Ltd | Professional & scientific | 2024 |
| Drjq Consulting Ltd | Administrative & support | 2018 |
| DRM JR Ltd | Professional & scientific | 2025 |
| Drome Architects LLP | | 2017 |
| Drone Captured Moments Limited | Information & communication | 2021 |
| Drone Power Ltd | Energy | 2020 |
| Drone Site Surveys Ltd | Professional & scientific | 2019 |
| Drone Zone Inspection and Surveys Limited | Manufacturing | 2022 |
| Dronegraphics UK Limited | Professional & scientific | 2021 |
| Dronezone Visuals Limited | Information & communication | 2025 |
| Drools Natural Treats Ltd | Wholesale & retail | 2025 |
| Droovy Ltd | Information & communication | 2016 |
| Drop Dead Gorgeous GB Ltd | Wholesale & retail | 2019 |
| Drop Watercoolers Ltd | Hospitality | 2025 |
| Dropme UK Ltd | Transport & logistics | 2025 |
| Dropswap Ltd | Health & social care | 2025 |
| Drosinos Limited | Professional & scientific | 2009 |
| Droswin Securities Trading Limited | Professional & scientific | 2018 |
| DRP Glass & Glazing Limited | Construction | 2014 |
| Drpt Birmingham Limited | Hospitality | 2009 |
| Drpt Liverpool Limited | Hospitality | 2008 |
| Drpt Properties Limited | Hospitality | 2009 |
| DRR Construction Group Ltd | Construction | 2023 |
| DRR Construction Limited | Construction | 2018 |
| DRR Management Property Limited | Real estate | 2017 |
| Drummond Corporations Ltd | Wholesale & retail | 2014 |
| Drummond House Investments Limited | Construction | 2023 |
| Drummond Property Limited | Hospitality | 2023 |
| Drummond Securities Limited | Real estate | 2026 |
| Drummoyne Court (Blundellsands) Limited | Households | 1962 |
| Drury Property Group Ltd | Real estate | 2025 |
| DRY Ice Supply (UK) Limited | Manufacturing | 2014 |
| Dryamee Limited | | 1978 |
| Drykela Brazilian Food Ltd | Manufacturing | 2023 |
| Drylam Capital Limited | Financial services | 2026 |
| Drylam Ltd | Wholesale & retail | 2024 |
| Dryline Solutions Ltd | Construction | 2024 |
| Dryon Limited | Wholesale & retail | 2025 |
| DS & Co Developments Limited | Construction | 2014 |
| DS Associates NW Ltd | Professional & scientific | 2019 |
| DS Buy and Sell Ltd | Wholesale & retail | 2025 |
| DS Care Properties Limited | Real estate | 2020 |
| DS Catering (NW) Ltd | Hospitality | 2019 |
| DS Cleaning Ltd | Administrative & support | 2026 |
| DS Clobber Ltd | Wholesale & retail | 2025 |
| DS Corner Limited | Hospitality | 2026 |
| DS Development (NW) Ltd | Real estate | 2025 |
| DS Food Takeaway Limited | Hospitality | 2023 |
| DS Handy MAN Ltd | Construction | 2025 |
| DS Operations Liverpool Limited | Hospitality | 2024 |
| DS Orthopaedic Services Ltd | Health & social care | 2020 |
| DS Wind Solutions Ltd | Professional & scientific | 2024 |
| DSB Group Properties Ltd | Real estate | 2026 |
| DSE (Data Storage) Limited | Administrative & support | 1995 |
| DSG Accountancy and Professional Services Limited | Professional & scientific | 2024 |
| DSG Accountancy and Taxation Services Limited | Administrative & support | 2019 |
| DSG Audit Services Limited | Professional & scientific | 2024 |
| DSG Trustee Services Limited | Professional & scientific | 2023 |
| DSG Wealth Management Limited | Financial services | 2018 |
| Dsgk Solutions Limited | Transport & logistics | 2020 |
| Dsgm Consult Ltd | Information & communication | 2023 |
| Dsgregory Limited | Information & communication | 2025 |
| DSI Deliveries Limited | Transport & logistics | 2015 |
| DSKL8 Limited | Education | 2019 |
| DSL Joinery Ltd | Construction | 2019 |
| DSM Accountancy Solutions Limited | Professional & scientific | 2011 |
| DSM Joinery Ltd | Construction | 2021 |
| DSM Teeth Care Limited | Health & social care | 2023 |
| Dsmc Joinery Limited | Construction | 2017 |
| Dsmediawallsandfireplaces Ltd | Construction | 2025 |
| Dsmt Ltd | Education | 2025 |
| Dsposal Ltd | Information & communication | 2016 |
| Dspro-Om Ltd | Wholesale & retail | 2022 |
| DSS Collective Community CIC | Administrative & support | 2026 |