| Double 66 Ltd | Wholesale & retail | 2024 |
| Double Glazing Repair Specialist Limited | Professional & scientific | 2010 |
| Double HIT Ltd | Information & communication | 2014 |
| Double S Motors Limited | Wholesale & retail | 1959 |
| Double SIX Holdings Limited | Other services | 2026 |
| Double SS Divine Healthcare Services Ltd | Public administration | 2020 |
| Doublechi Ltd | Professional & scientific | 2024 |
| Doubter to Believer Limited | Wholesale & retail | 2026 |
| Doufre Construction Personnel Ltd | Administrative & support | 2019 |
| Dougies Delivery’S Ltd | Hospitality | 2025 |
| Douglas Court (Southport) Management Limited | Households | 1973 |
| Douglas Forestry LLP | | 2012 |
| Douglas Property Developments Ltd | Real estate | 2006 |
| Douglas Property Investors Ltd | Real estate | 2019 |
| Douglas White Limited | Financial services | 2012 |
| Doukkon Catering Ltd | Hospitality | 2014 |
| Doulaitou Management Limited | Real estate | 2019 |
| Doux Chaton Holdings Ltd | Financial services | 2025 |
| Doux Chaton Limited | Hospitality | 2021 |
| DOV Construction & Repairs Ltd | Construction | 2025 |
| Dovecot Cottage Management Company Limited | Households | 2000 |
| Dovecot Foods Ltd | Hospitality | 2025 |
| Dovecot Pizza Limited | Hospitality | 2024 |
| Dovecot Place Pizza L14 Ltd | Hospitality | 2025 |
| Dovedale Mews Management Company Limited | Real estate | 2003 |
| Dover Express Ltd | Wholesale & retail | 2020 |
| Dovestone Bistro Ltd | Hospitality | 2024 |
| Dovewell Training Limited | Education | 2017 |
| Dovey Barbers Ltd | Other services | 2024 |
| Dowd Geotechnical Services Ltd | Professional & scientific | 2022 |
| Dowd International Ltd | Other services | 2022 |
| Dowd Property Group Limited | Real estate | 2026 |
| Dowhigh Limited | Construction | 1975 |
| Dowling Care Holdings Limited | Financial services | 2022 |
| Dowling Digital Ltd | Information & communication | 2017 |
| Down to Earth Groundwork and Plant Hire Limited | Construction | 2016 |
| Downhead Ventures LP | | 2018 |
| Downing Construction Ltd | Construction | 2017 |
| Downing Living Ltd | Real estate | 2019 |
| Downing Living South Ltd | Real estate | 2019 |
| Downing Living Southside Ltd | Real estate | 2019 |
| Downing Properties Limited | Real estate | 2025 |
| Downing Property Management Limited | Real estate | 2013 |
| Downing Property Services Limited | Real estate | 2002 |
| Downing Sports Management Limited | Arts & recreation | 2017 |
| Downland Home Limited | Financial services | 2018 |
| Downland Ventures Limited | Financial services | 2025 |
| Downs Maintenance(Blundellsands)Limited(The) | Households | 1975 |
| Downs Variava Architecture Limited | Professional & scientific | 2008 |
| Downton Construction Ltd | Construction | 2011 |
| Downtown in Business Events Ltd | Other services | 2023 |
| Downtown in Business Ltd | Administrative & support | 2004 |
| Downtown Liverpool in Business Limited | Professional & scientific | 2007 |
| Downtown Preston in Business Limited | Professional & scientific | 2006 |
| Dowridge Homes Ltd | Construction | 2023 |
| Doyle & Co Property Ltd | Real estate | 2026 |
| Doyle Properties (Liverpool) Limited | Hospitality | 2016 |
| Doylester 78 Limited | Administrative & support | 2017 |
| Doylester 79 Limited | Administrative & support | 2017 |
| Doylester Twenty Five Limited | Administrative & support | 2006 |
| DP and Marine Assurance (UK) Limited | Professional & scientific | 2015 |
| DP Couriers Ltd | Transport & logistics | 2026 |
| DP Owens Construction Ltd | Construction | 2024 |
| DP Visuals Ltd | Information & communication | 2025 |
| Dparts Ltd | Education | 2023 |
| DPD Management Company Ltd | Professional & scientific | 2001 |
| DPF Consultancy Ltd | Professional & scientific | 2025 |
| DPG Shop Limited | Wholesale & retail | 2026 |
| DPJ Developments NW Limited | Real estate | 2024 |
| DPJ Management Limited | Real estate | 2021 |
| DPJ Property Investment Group Limited | Real estate | 2025 |
| DPL Estates Ltd | Real estate | 2023 |
| DPM Financial Solutions Ltd | Financial services | 2013 |
| DPP Partners Ltd | Real estate | 2012 |
| Dprv Ltd | Professional & scientific | 2013 |
| DPS Hygiene Ltd | Administrative & support | 2022 |
| DPS Plastering Ltd | Construction | 2013 |
| DPS Vans Ltd | Wholesale & retail | 2025 |
| DR 1D Limited | Real estate | 2023 |
| DR a F Medical Services Limited | Health & social care | 2025 |
| DR Afshin Khalatbari Ltd | Health & social care | 2019 |
| DR Andrew Morgan Positive Psychology Ltd | Health & social care | 2022 |
| DR Andy Brown Limited | Health & social care | 2022 |
| DR Ayman Aboreeda Medical Limited | Health & social care | 2023 |
| DR Baldock's Aesthetic Clinic Ltd | Health & social care | 2025 |
| DR Business Services Limited | Wholesale & retail | 2003 |
| DR C Medical Ltd | Health & social care | 2024 |
| DR Cindy Clinics Ltd | Health & social care | 2023 |
| DR Construct Ltd | Construction | 2021 |
| DR Costas Papageorgiou Limited | Health & social care | 2013 |
| DR Daryanani Ltd | Real estate | 2019 |
| DR Dave's Entertainments Ltd | Arts & recreation | 2012 |
| DR Dromey Limited | Health & social care | 2016 |
| DR Ehab Hamouda Ltd | Health & social care | 2022 |
| DR Feel Good UK Ltd | Wholesale & retail | 2025 |
| DR Fiona Macrae Aesthetics Ltd | Professional & scientific | 2015 |
| DR G J & MRS S J Adam Trading Limited | Professional & scientific | 2019 |
| DR Homes and Properties Ltd | Real estate | 2025 |
| DR Hospitality Ltd | Hospitality | 2024 |
| DR Innovative Products Limited | Professional & scientific | 2017 |