| DE Silva Women's Health Ltd | Health & social care | 2024 |
| DE Support Solutions Ltd | Professional & scientific | 2025 |
| DE Telecoms Ltd | Construction | 2019 |
| DE Vere Facilities Management Limited | Construction | 2020 |
| DEA Group Limited | Financial services | 2019 |
| Deaconos Taylor Ltd | Other services | 2026 |
| Dead Air Records Limited | Wholesale & retail | 2023 |
| Dead Crafty Allerton Ltd | Hospitality | 2025 |
| Dead Inside Design Ltd. | Wholesale & retail | 2020 |
| Deadline Construction Services Ltd | Construction | 2019 |
| Deadlive Limited | Wholesale & retail | 2025 |
| Deafersify CIC | Arts & recreation | 2021 |
| Deal Bridge Limited | Wholesale & retail | 2024 |
| Deal Properties Limited | Real estate | 2019 |
| Dealcrest Limited | Real estate | 1998 |
| Dealga's Tree Consultancy Ltd | Administrative & support | 2011 |
| Dealingwithwellness Limited | Health & social care | 2024 |
| Deals on Wheelz Ltd | Wholesale & retail | 2025 |
| Dean Alexander Energy Consultants Limited | Professional & scientific | 2021 |
| Dean Alexander Properties Limited | Real estate | 2021 |
| Dean Brothers (Formby) Limited | Other services | 1946 |
| Dean L Dalton Ltd | Administrative & support | 2012 |
| Dean Parkins Ltd | Construction | 2015 |
| Dean W Limited | Financial services | 2014 |
| Deanandrewmaintenancemanagementservices Ltd | Manufacturing | 2021 |
| Deandove Ltd | Real estate | 2004 |
| Deano's Care Limited | Health & social care | 2019 |
| Deans Court (Formby) Management Company Limited | Households | 1977 |
| Deansgate Law Limited | Extraterritorial | 2015 |
| Dearbridge Consulting Limited | Professional & scientific | 2019 |
| Dearbridge Investments Limited | Real estate | 2018 |
| Dears Safety Management Ltd | Professional & scientific | 2024 |
| Dearsmith Investments Limited | Real estate | 2019 |
| Dearyou Ltd | Wholesale & retail | 2025 |
| Debbie Knight Property Services Ltd | Real estate | 2020 |
| Deborah's Food Limited | Hospitality | 2019 |
| Debre Bsrat Kudus Urael Eritrean Orthodox Church Liverpool CIC | Other services | 2024 |
| Debre Selam Kudus Urael Eritrean Orthodox Tewahdo Church | Other services | 2022 |
| Debt Health Check Limited | Other services | 2012 |
| Decent Donuts Limited | Wholesale & retail | 2021 |
| Decima (NW) Limited | Professional & scientific | 2018 |
| Deckho LLP | | 2020 |
| Decko Maintenance Ltd | Construction | 2023 |
| Deco 11 - UK Conduit 3 Holding Limited | Administrative & support | 2006 |
| Deco 11 - UK Conduit 3 P.L.C. | Administrative & support | 2006 |
| Decomm Metals Ltd | Professional & scientific | 2021 |
| Decompass Limited | Information & communication | 2024 |
| Decon Properties Limited | Real estate | 2000 |
| Decoration Pro Expert Ltd | Construction | 2022 |
| Decorative Logs Ltd | Wholesale & retail | 2024 |
| Decorex (NW) Ltd | Construction | 2016 |
| Decorex (NWE) Ltd | Construction | 2019 |
| Decoy Barns Property Management Company Limited | Extraterritorial | 2013 |
| Decrevi Distribution Ltd | Wholesale & retail | 2022 |
| Decs Clobber Ltd | Wholesale & retail | 2025 |
| Dedicated Football Development CIC | Education | 2024 |
| Dedicated OPS Ltd | Arts & recreation | 2026 |
| Dedicated Supergym Ltd | Arts & recreation | 2019 |
| Dedomena Data Limited | Administrative & support | 2020 |
| DEE & DEE Catcare Ltd | Manufacturing | 2025 |
| DEE Creative Limited | Information & communication | 2023 |
| DEE Delicious Catering & Events Ltd | Hospitality | 2018 |
| DEE KAY Maintenance Limited | Construction | 2011 |
| DEE Waterloo Limited | Hospitality | 2026 |
| Dee-Velop Heswall Ltd | Construction | 2025 |
| Deeahealth Ltd | Health & social care | 2023 |
| Deeconic Holdings Ltd | Financial services | 2020 |
| Deeconic Libra Ltd | Construction | 2022 |
| Deeconic Orion Ltd | Real estate | 2021 |
| Deeconic Property Investments Ltd | Construction | 2023 |
| Deeds Liverpool Limited | Real estate | 2023 |
| Deeds Property Maintenance Limited | Real estate | 2023 |
| Deeklo Ltd | Wholesale & retail | 2025 |
| Deenatech Ltd | Information & communication | 2025 |
| Deep Electric Ltd | Wholesale & retail | 2022 |
| Deep Escape Ltd | Administrative & support | 2026 |
| Deep Ideas Ltd | Wholesale & retail | 2008 |
| Deep Tissue Liverpool Ltd | Other services | 2025 |
| Deepakkeshari Limited | Information & communication | 2025 |
| Deepaulo Limited | Health & social care | 2015 |
| Deeppan Express Limited | Hospitality | 2018 |
| Deeralba North West Limited | Wholesale & retail | 2023 |
| Defendernauts Ltd | Information & communication | 2025 |
| Define Fitness Falkirk Ltd | Arts & recreation | 2025 |
| Defined by G Limited | Other services | 2024 |
| Definitive 1 Limited | Manufacturing | 2002 |
| Defrig Medical Diagnostic Imaging Global Intreprenuer Limited | Health & social care | 2021 |
| Degil Limited | Households | 2019 |
| Degsy FAY Hairdressing Services Ltd | Other services | 2015 |
| Dehuss Ltd | Real estate | 2025 |
| Deimos Holdings Ltd | Financial services | 2024 |
| Deira DB Securities Ltd | Real estate | 2006 |
| Dejas Natural Ltd | Manufacturing | 2025 |
| Dejon Holdings Limited | Financial services | 2025 |
| Dejon Trading Limited | Professional & scientific | 2025 |
| Dekiru Ltd | Information & communication | 2019 |
| Del's Dynasty Ltd | Administrative & support | 2020 |
| Delaware Allotments CIC | Health & social care | 2019 |
| Deli Stitches Ltd | Other services | 2026 |
| Delicious Creative Ltd | Information & communication | 2013 |