| P R Build (Tempsford) Limited | Construction | 2025 |
| P R Build Holdings Ltd | Financial services | 2021 |
| P R Build Ltd. | Construction | 1997 |
| Paige Toon Ltd | Information & communication | 2013 |
| Pain and Sons Limited | Health & social care | 2024 |
| Perry Sharman Property Ltd | Real estate | 2016 |
| Pete Marsh Consulting Limited | Professional & scientific | 2014 |
| Pharma Delivery Device Consulting Ltd | Professional & scientific | 2014 |
| Pizza Mondo Street Food Ltd | Hospitality | 2019 |
| Ponsonby Associates Ltd | Professional & scientific | 2021 |
| Potential ETC Ltd | Professional & scientific | 2013 |
| Potential Homes Ltd | Real estate | 2019 |
| Power Drive Efficiency Limited | Manufacturing | 2014 |
| PRB Developments Ashley Limited | Construction | 2022 |
| Rainbow Medical Engineering Limited | Manufacturing | 2006 |
| Rainbow Ultrasonics Limited | Extraterritorial | 2013 |
| Ramsey Ruby Ltd | Construction | 2017 |
| Raremet Limited | Financial services | 2011 |
| RAV RX Limited | Professional & scientific | 2023 |
| RDB Progressive Solutions Ltd | Education | 2015 |
| Rectory Developments Anglesey Ltd | Construction | 2014 |
| Rees International Holdings Limited | Professional & scientific | 2023 |
| Renewable Specialist Limited | Professional & scientific | 2014 |
| Reportl Ltd | Information & communication | 2024 |
| RH Building Consultancy Limited | Professional & scientific | 2011 |
| RH Commercial Holdings Ltd | Financial services | 2019 |
| RJ Care Ltd | Health & social care | 2022 |
| RJT Consultancy Ltd | Professional & scientific | 2018 |
| Roka Advisory Limited | Professional & scientific | 2015 |
| Rolo Advisory Limited | Professional & scientific | 2025 |
| Royston Solar Solutions Limited | Construction | 2022 |
| Ruggles Plumbing and Heating Ltd | Construction | 2010 |
| Rwrr (IP) Ltd | Administrative & support | 2024 |
| Sallows Properties Limited | Real estate | 2026 |
| Sandycoombe Limited | Professional & scientific | 2011 |
| Sarnmere Consulting Ltd | Professional & scientific | 2011 |
| Sarnmere Properties Limited | Real estate | 2013 |
| Schooner Transport Limited | Transport & logistics | 2007 |
| SG & GF Investments Limited | Real estate | 2024 |
| Simmo Services Limited | Professional & scientific | 2025 |
| Sky Data Services Ltd | Information & communication | 2017 |
| Span Organisational Engineering Ltd | Professional & scientific | 2015 |
| Speade Limited | Administrative & support | 2013 |
| Spires-Jones Neuroscience Ltd | Professional & scientific | 2025 |
| SR Company Services Limited | Administrative & support | 2000 |
| SSG Tech Consultancy Ltd | Information & communication | 2021 |
| Stanes Rand Business Services Limited | Professional & scientific | 1999 |
| Steam Wine Bar Ltd | Hospitality | 2005 |
| Stemma Land and New Homes Ltd | Construction | 2019 |
| STG Mortgage Solutions Ltd | Financial services | 2022 |
| Stones of Cambridge Ltd | Construction | 2023 |
| Stuart Croft Financial Services Limited | Financial services | 2017 |
| Style Discount UK Ltd | Wholesale & retail | 2016 |
| Sunlite Carports Limited | Manufacturing | 2024 |
| Surrigo Ltd | Professional & scientific | 2012 |
| Sustainable Success Ltd | Professional & scientific | 2022 |
| THE Big Green Generator Company Ltd | Administrative & support | 2019 |
| THE Cambridge Cider Company Limited | Manufacturing | 2023 |
| THE Digital Rainbow Limited | Information & communication | 2019 |
| THE Euro Special Limited | Real estate | 2005 |
| THE Jobs Board Company Ltd | Administrative & support | 2016 |
| THE Living Room Landscapes Limited | Administrative & support | 2011 |
| THE Madisons Experience Ltd | Wholesale & retail | 2015 |
| THE Old Grain Store Limited | Real estate | 2021 |
| THE View Bureau Ltd | Professional & scientific | 2018 |
| Thompson Taraz Rand Group Limited | Professional & scientific | 2018 |
| Three Little Kiwis Ltd | Hospitality | 2020 |
| Thurston Roofing Limited | Construction | 2013 |
| Tigerlab Limited | Information & communication | 2017 |
| Tojeiro Limited | Extraterritorial | 2014 |
| Torx Software Ltd | Professional & scientific | 2020 |
| Trans Global Logistics UK Limited | Administrative & support | 2008 |
| Trivium Technical Authors Limited | Information & communication | 2013 |
| Tuncer Group Limited | Real estate | 2024 |
| Two Highworth Limited | Real estate | 2026 |
| Unic Hospitality Ltd | Information & communication | 2007 |
| Vhayes Regulatory Consulting Ltd | Professional & scientific | 2023 |
| Vitalis Ortho Ltd | Manufacturing | 2025 |
| W D Chipchase Limited | Construction | 2010 |
| Wakebro Construction Ltd | Construction | 2021 |
| Walker Planning & Construction Limited | Professional & scientific | 2002 |
| Waterbeach Stud Ltd | Agriculture & fishing | 2016 |
| Wheeler Science Medicine & Education Ltd | Health & social care | 2012 |
| Widerpool Limited | Professional & scientific | 2013 |
| Wiggbros Holdings Limited | Financial services | 2019 |
| Wild Monday Resilience Ltd | Other services | 2018 |
| Wilkinson London Limited | Professional & scientific | 2022 |
| Woods Distribution Group Ltd | Real estate | 2025 |
| Worly Farm Fisheries Ltd | Wholesale & retail | 2025 |