| Riada Partners Limited | Professional & scientific | 2017 |
| Rich Baking Ltd | Manufacturing | 2016 |
| Richardson Cardy Ltd | Manufacturing | 2015 |
| Richmond Coach Hire Ltd | Extraterritorial | 2021 |
| Richmond Coach Services Ltd | Extraterritorial | 2021 |
| Richmond Coaches Ltd | Transport & logistics | 2012 |
| Rickzor Ltd | Health & social care | 2024 |
| Ride Life Above Ltd | Wholesale & retail | 2025 |
| Rigid Rentals Ltd | Real estate | 2026 |
| Rimax Integrated Services Ltd | Wholesale & retail | 2023 |
| RIO Bingo Dungannon Ltd | Arts & recreation | 2015 |
| Rioga Banjos Ltd | Manufacturing | 2023 |
| Rion PTE Ltd | Wholesale & retail | 2025 |
| Riseon Ltd | Financial services | 2024 |
| Riverlands Therapy Ltd | Health & social care | 2025 |
| Rjsd N.I. Limited | Administrative & support | 2020 |
| RK Auto Sales Ltd | Wholesale & retail | 2026 |
| RLC Financial Solutions Limited | Financial services | 2006 |
| RLS Plant Sales Ltd | Administrative & support | 2021 |
| Robert Craig & Sons Limited | Manufacturing | 2007 |
| Robert Kirk Flooring Limited | Wholesale & retail | 2014 |
| Robin's Nest Investments Limited | Real estate | 2019 |
| ROC Golf Ltd | Manufacturing | 2018 |
| Rocdrill Limited | Mining & quarrying | 1996 |
| Rochelou Consulting Firm LP | | 2020 |
| Rock Extraction Limited | Wholesale & retail | 2014 |
| Rockhampton Properties Limited | Manufacturing | 2024 |
| Rodgers Community Care Ltd | Health & social care | 2012 |
| Rodyk Capital Limited | Real estate | 2024 |
| Rogmar Associates Ltd | Professional & scientific | 2025 |
| Rokeby Holdings Ltd | Professional & scientific | 2022 |
| Ronnie Thompson | Other services | 2006 |
| Rookwood Trading Ltd | Administrative & support | 2019 |
| Rosebroom | Financial services | 2026 |
| Rosepark Holdings Ltd | Professional & scientific | 2003 |
| Rosnashane Holdings Ltd | Hospitality | 2020 |
| Rowantree Stone Ltd | Manufacturing | 2015 |
| Rowantree Stoneworks Limited | Construction | 1995 |
| Royal Pizza and Kebabs Ltd | Hospitality | 2026 |
| RPM Motors Ltd | Wholesale & retail | 2019 |
| RPM Motorsport Ltd | Wholesale & retail | 2019 |
| RR Props Ltd | Information & communication | 2019 |
| RT Tech Holdings Ltd | Construction | 2025 |
| Rubcon Contracts Ltd | Construction | 2024 |
| Rubeus Flow Ltd | Health & social care | 2020 |
| Rumbles Lisburn Ltd | Hospitality | 2016 |
| Rumour Mill Creative Communications Limited | Professional & scientific | 2018 |
| Run With Passion Ltd | Arts & recreation | 2019 |
| Rupert Hunter Ltd | Real estate | 2023 |
| Rural Fitness Limited | Arts & recreation | 2023 |
| Russell Engineering Ltd | Extraterritorial | 2021 |
| Russell Lead Roofing Ltd | Construction | 2022 |
| Russula Trade LP | | 2020 |
| Ruthless Media Services Ltd | Information & communication | 2019 |
| RW Electrical Contracts Limited | Construction | 2025 |
| Rwca Ltd | Professional & scientific | 2012 |
| Ryvon Consulting Limited | Professional & scientific | 2019 |
| S & D Developments Limited | | 2007 |
| S Berry Family Butchers Ltd | Wholesale & retail | 2015 |
| S D Brown (Funeral Directors) Ltd | Other services | 2007 |
| S K Ballyclare Takeaway Ltd | Hospitality | 2019 |
| S K Couriers (2017) Ltd | Transport & logistics | 2017 |
| S Knox Construction Services Limited | Construction | 2018 |
| S M D Associates Ltd | Administrative & support | 1999 |
| S Mckee Transport Services Limited | Transport & logistics | 2025 |
| S Robinson Shopfitting Ltd | Manufacturing | 2014 |
| S. and S. Developments (N.I.) Limited | Real estate | 1988 |
| S.C ENG Ltd | Manufacturing | 2021 |
| S1GNO Ltd | Professional & scientific | 2020 |
| Sabari NI Limited | Health & social care | 2018 |
| Safana Films Ltd | Information & communication | 2024 |
| Safe Secure Save Ltd | Construction | 2015 |
| Safety First Display Ltd | Manufacturing | 2024 |
| Safety Matters of NI Ltd | Education | 2023 |
| Safety Solutions (N.I.) Ltd | Other services | 1999 |
| Saikung Night Lisburn Ltd | Hospitality | 2023 |
| Salar IT Limited | Information & communication | 2018 |
| Salisbury Apartments Management Company Limited | Households | 2011 |
| Salt Factory Sports | Education | 2012 |
| Salta Services (NI) Limited | Administrative & support | 2004 |
| Salto Gymnastic Centre Limited | Arts & recreation | 1999 |
| Saltroad Ltd | Health & social care | 2024 |
| SAM Baird Ltd | Health & social care | 2010 |
| Sanders & Morrison Holding Limited | Arts & recreation | 2024 |
| Sandy Bay Civils Limited | Construction | 2023 |
| Sandymount Close Management Co. Ltd | Construction | 2009 |
| Sanla Limited | Construction | 2018 |
| Santry Properties Limited | Construction | 2007 |
| Sarvic Properties Ltd | Real estate | 2022 |
| Sauce Almighty (NI) Limited | Hospitality | 2014 |
| Sauce Almighty Limited | Hospitality | 2014 |
| SC Capital Projects Ltd | Construction | 2021 |
| SC Gardening Limited | Other services | 2016 |
| Scaffold Digital Ltd | Information & communication | 2015 |
| Scangen (UK) Limited | Extraterritorial | 2000 |
| SCF Homes Ltd | Real estate | 2023 |
| Schapiro Limited | Administrative & support | 2005 |
| Schoon Technology Ltd | Manufacturing | 2025 |
| Scorpio Inst. of Pole Ltd | Arts & recreation | 2024 |
| Scotjacksolutions Ltd | Professional & scientific | 2020 |