| Duval Morgan Limited | Real estate | 1991 |
| DW Landscaping & Fencing Limited | Administrative & support | 2023 |
| Dwane Plumbing and Heating Limited | Construction | 2014 |
| DX3WEBS Limited | Information & communication | 2012 |
| Dycote Farms Limited | Agriculture & fishing | 1956 |
| Dylan's Barber Shop Limited | Other services | 2015 |
| Dyluxe Group Ltd | Wholesale & retail | 2026 |
| Dynami Properties Ltd | Real estate | 2023 |
| Dynamic Access Solutions Limited | Manufacturing | 2013 |
| Dynamic Consultancy Specialists Limited | Professional & scientific | 2020 |
| Dynamic Management Solutions (M) Limited | Administrative & support | 2025 |
| Dynamo Business Advisory Limited | Professional & scientific | 2025 |
| Dyson Farming Limited | Financial services | 2009 |
| Dziedzic Transport Ltd | Transport & logistics | 2013 |
| E & a Metals Ltd | Wholesale & retail | 2024 |
| E a Sharpe Limited | Professional & scientific | 2000 |
| E Ancius Ltd | Transport & logistics | 2023 |
| E and R Cars Lincoln Ltd | Transport & logistics | 2021 |
| E Assist Ltd | Information & communication | 2019 |
| E B (Lincoln) Limited | Real estate | 2005 |
| E C One Ltd | Administrative & support | 2025 |
| E Carapeti Limited | Health & social care | 2009 |
| E Hutton Construction Ltd | Construction | 2025 |
| E Jackson Accounting Ltd | Professional & scientific | 2024 |
| E M Howard Limited | Agriculture & fishing | 1956 |
| E V Motion Limited | Extraterritorial | 2021 |
| E&B Building Ltd | Construction | 2025 |
| E&E African Store Limited | Wholesale & retail | 2025 |
| E&E Healthcare Limited | Health & social care | 2023 |
| E&R Supplies Ltd | Wholesale & retail | 2020 |
| E-Ever Ltd | Wholesale & retail | 2025 |
| E-Maks Homes Limited | Health & social care | 2026 |
| E.& J.Barlow Limited | Construction | 1966 |
| E.A.Dring(Farms)Limited | Agriculture & fishing | 1958 |
| E.C. Group Holdings Ltd | Information & communication | 2010 |
| E.D.B. Design Ltd | Manufacturing | 2024 |
| E.I.C.S. Products Limited | Manufacturing | 2012 |
| E.J.M. Plumbing & Heating Limited | Construction | 2009 |
| E.K Transport HGV Ltd | Transport & logistics | 2018 |
| E2P Global Ltd | Wholesale & retail | 2026 |
| Eagle Electrical (Lincs) Limited | Construction | 2007 |
| Eagle EYE Bidco Limited | Financial services | 2025 |
| Eagle EYE Innovations Ltd | Professional & scientific | 2013 |
| Eagle EYE Midco Limited | Financial services | 2025 |
| Eagle EYE Topco Limited | Financial services | 2025 |
| Eagle Hall Estates Limited | Professional & scientific | 2002 |
| Eagle Mortgages & Protection Ltd | Financial services | 2022 |
| Eagle X Talent Limited | Professional & scientific | 2026 |
| Eagle-Age Concepts Ltd | Water & waste | 2024 |
| Eagles Coaching Ltd | Education | 2024 |
| Ealing Classics Limited | Administrative & support | 2010 |
| Eardwic Ltd | Real estate | 2019 |
| Earl of Ermine Ltd | Real estate | 2018 |
| Earlybird Lifestyle Support Ltd | Administrative & support | 2019 |
| Earrn Ltd | Information & communication | 2021 |
| Easilett Ltd | Real estate | 2012 |
| East Bridge Electricals Limited | Construction | 2008 |
| East Coast Classics Ltd | Wholesale & retail | 2023 |
| East Coast Infrastructure Services Ltd | Construction | 2024 |
| East Coast Padel Grantham Limited | Arts & recreation | 2026 |
| East Lake 421 Limited | Hospitality | 2024 |
| East Leake Holdings Limited | Financial services | 2023 |
| East Midlands Community LED Housing CIC | Other services | 2012 |
| East Midlands Plumbers Limited | Construction | 2015 |
| East Mids Drainage Ltd | Construction | 2024 |
| East Sussex Residential Parks Ltd | Households | 2018 |
| East Village (North Hykeham) Management Company Limited | Households | 2021 |
| Eastern Industrial Door Services Ltd | Manufacturing | 2008 |
| Eastfield Commercial Services Limited | Professional & scientific | 2015 |
| Eastfield Enterprises Limited | Manufacturing | 1971 |
| Eastfield Yurts Ltd | Hospitality | 2011 |
| Eastgate Club Lincoln Ltd | Arts & recreation | 2023 |
| Eastgate Construction (Lincoln) Limited | Real estate | 2004 |
| Eastments Garage Ltd. | Wholesale & retail | 2015 |
| Eastmills Court (Heighington) Management Company Ltd. | Real estate | 1989 |
| Easy Drain (East Midlands) Ltd | Other services | 2016 |
| Easy Hire (Lincs) Ltd | Administrative & support | 2015 |
| Easyglaze (Lincoln) Ltd | Construction | 2008 |
| Easylifesupplies Limited | Wholesale & retail | 2026 |
| Easyroute IT Ltd | Information & communication | 2014 |
| EAT Sleep Padel Limited | Arts & recreation | 2025 |
| Eaton IT Services Limited | Professional & scientific | 2025 |
| Ebcon Publishing Limited | Information & communication | 2005 |
| Echo One Design LLP | | 2019 |
| Echo Ready Systems Limited | Information & communication | 2015 |
| ECI Software Solutions Europe Holdings Limited | Professional & scientific | 2006 |
| ECI Software Solutions Limited | Information & communication | 2001 |
| Ecis Renewables Ltd | Construction | 2026 |
| Eclat Entertainment Limited | Administrative & support | 2026 |
| Eclipse Design and Management Limited | Administrative & support | 1999 |
| Eclipse Farm Ltd | Wholesale & retail | 2010 |
| Eclipse Fencing Ltd | Wholesale & retail | 2010 |
| Eco Energy Systems Ltd | Energy | 2024 |
| Eco Packaging Ltd | Administrative & support | 2014 |
| Eco Property Solutions (East Midlands) Ltd | Real estate | 2024 |
| Eco Saint Ltd | Professional & scientific | 2023 |
| Eco-Friendly Events Limited | Manufacturing | 2021 |
| Eco-Mining Capital Ltd | Information & communication | 2020 |
| Eco-Ren Property Services Ltd | Construction | 2014 |
| Ecomal UK Limited | Wholesale & retail | 2001 |