| Nexacart Digital Ltd | Wholesale & retail | 2026 |
| Nexpro Ltd | Wholesale & retail | 2023 |
| NFS Electrical Ltd | Construction | 2023 |
| NG Optical Ltd | Health & social care | 2026 |
| Niche IT Projects UK Limited | Information & communication | 2018 |
| Nico-Andy Limited | Other services | 2015 |
| Nifty Aura Creations Ltd | Manufacturing | 2025 |
| Nigel Thompson Trading Company Limited | Real estate | 1980 |
| Nine Consulting Services Ltd | Information & communication | 2016 |
| Nisha Associate Ltd | Information & communication | 2025 |
| NMB Interiors Ltd | Construction | 2024 |
| NMB Kitchen & Builders Limited | Construction | 2018 |
| NMB Kitchens & Bathrooms Ltd | Construction | 2024 |
| NME Properties Limited | Real estate | 2024 |
| NO Metric Limited | Information & communication | 2024 |
| Noble Motor Comapny GB Ltd. | Wholesale & retail | 2015 |
| Nomad Leigh Ltd | Hospitality | 2026 |
| Nordic Interiors Limited | Wholesale & retail | 2025 |
| Normanhurst Sale Ltd | Real estate | 2017 |
| Northern Marketing Ltd | Extraterritorial | 2024 |
| Northern Platforms Limited | Manufacturing | 1984 |
| Northmen Communities CIC | Arts & recreation | 2021 |
| Northwest Bearings Ltd | Wholesale & retail | 2020 |
| Norymus Limited | Other services | 2026 |
| Noub Home Care Services Ltd | Health & social care | 2025 |
| Nova Electrical & Maintenance Ltd | Professional & scientific | 2026 |
| Novaryn Holdings Ltd | Financial services | 2026 |
| Novawave Brands Ltd | Wholesale & retail | 2026 |
| NQ Burgers Ltd | Hospitality | 2025 |
| Nufeet Podiatry Ltd | Health & social care | 2019 |
| Number Plate Guru Ltd | Manufacturing | 2024 |
| NWL Petite Performers Ltd | Education | 2026 |
| Nzuko NDI Old IMO Manchester (Nnim) CIC | Health & social care | 2022 |
| O & L Property Investments Ltd | Real estate | 2023 |
| O'Neills Vending Ltd | Wholesale & retail | 2025 |
| O10 Properties Limited | Real estate | 2025 |
| Oak Tree (Construction Design & Management) Limited | Construction | 2010 |
| OBA Rail Ltd | Construction | 2019 |
| Obsidian Enterprise Ltd | Manufacturing | 2026 |
| Occura Workforce Health and Wellbeing Ltd | Health & social care | 2025 |
| Ocean's 11 Ltd | Hospitality | 2023 |
| Official PIT Wars Ltd | Arts & recreation | 2025 |
| OH My Gast Ltd | Professional & scientific | 2022 |
| OH SO British Events Limited | Hospitality | 2018 |
| Ohio Properties Limited | Hospitality | 2021 |
| Ohyes Ltd | Wholesale & retail | 2023 |
| OJM Developments Ltd | Real estate | 2025 |
| Okapi Trading Ltd | Wholesale & retail | 2019 |
| Old Block Chippy Ltd | Hospitality | 2025 |
| Old Henry Street MC Limited | Health & social care | 2024 |
| Omega Developments (North West) Ltd | Real estate | 2022 |
| OMO Building Services Ltd | Construction | 2026 |
| Omoruyi Impex Limited | Transport & logistics | 2023 |
| Onyx NOW Ltd. | Wholesale & retail | 2019 |
| Open Space First Ltd | Construction | 2021 |
| Open View Windows Ltd | Construction | 2025 |
| Opengate- VENTURES2000 Limited | Health & social care | 2022 |
| Openshaw Refrigeration Ltd | Construction | 2025 |
| Optoplus Ltd | Professional & scientific | 1996 |
| Orange Civils Ltd | Administrative & support | 2016 |
| Orange Grove Kitchen Limited | Hospitality | 2023 |
| Orchid Leisure Limited | Hospitality | 2008 |
| Orchmere Tech Limited | Information & communication | 2025 |
| Oremii Media Ltd | Information & communication | 2025 |
| ORO MIO Ltd | Hospitality | 2026 |
| Orsos Courier Services Ltd | Transport & logistics | 2019 |
| Osemu Services Limited | Health & social care | 2019 |
| Owerre Welfare Community Manchester Ltd | Extraterritorial | 2024 |
| Owerre Welfare Community Greater Manchester CIC | Health & social care | 2023 |
| P & T Motors Limited | Wholesale & retail | 1988 |
| P B and K J Management Limited | Professional & scientific | 2018 |
| P D Jones Joinery Contractor Limited | Construction | 2004 |
| P&Puk Ltd | Wholesale & retail | 2026 |
| P. Wilson Joinery Ltd | Construction | 2004 |
| P.Collins Plumbing & Tiling Ltd | Construction | 2026 |
| PAB 74 Ltd | Extraterritorial | 2016 |
| PAB Architects Limited | Professional & scientific | 2012 |
| PAB Investments (Leigh) Limited | Construction | 2006 |
| Paka Transport Limited | Transport & logistics | 2016 |
| Palace Builders Merchant Ltd | Construction | 2023 |
| Palatine Paints & Chemicals Limited | Manufacturing | 2011 |
| Panache Auto Repairs Ltd | Wholesale & retail | 2025 |
| Parkone Facilities Ltd | Transport & logistics | 2025 |
| Parks Surgery Limited | Health & social care | 2021 |
| Parr Digital Promotions Ltd | Wholesale & retail | 2025 |
| Parsonage Commercials Ltd | Wholesale & retail | 2025 |
| PASSION2024 Ltd | Hospitality | 2024 |
| Passivefireprotect Ltd | Construction | 2026 |
| Patrick Contract Joinery Limited | Construction | 1997 |
| Patrick Developments Limited | Real estate | 1998 |
| Paul Jones Transport Limited | Transport & logistics | 1992 |
| Paul Lester Transport Ltd | Transport & logistics | 2018 |
| PAW Meds Online Ltd | Wholesale & retail | 2026 |
| Paws Doggy Day Care Leigh Ltd | Administrative & support | 2017 |
| Payrica Limited | Information & communication | 2025 |
| PB Plumbing & Property Limited | Construction | 2019 |
| PC Planning Limited | Information & communication | 2023 |
| PDL Management Ltd | Construction | 2006 |
| PDW (Leigh) Limited | Financial services | 2010 |
| Pe&Ra Limited | Professional & scientific | 2023 |