| Dolphin Poland LLP | | 2010 |
| Dolphin Staff LLP | | 2004 |
| Dominic at David North Limited | Manufacturing | 2004 |
| Donington Enterprises Limited | | 1982 |
| Drive Holdings 2015 Limited | Wholesale & retail | 2015 |
| Drive Investments Limited | Wholesale & retail | 2011 |
| Druck Limited | Manufacturing | 1981 |
| Drummondance Limited | Arts & recreation | 2003 |
| Dura-Sport (Leisure Care) Ltd | Construction | 2000 |
| Dura-Sport Limited | Construction | 1995 |
| DW Asset Management Ltd | Financial services | 2025 |
| Dynamic Personnel Ltd | Administrative & support | 2021 |
| E Taylor Skip Hire & Recycling Limited | Real estate | 2003 |
| E. M. Turcan & Partners | | 1992 |
| E.H.G. Limited | Households | 1980 |
| E.M.C. International Consultants Limited | Wholesale & retail | 1998 |
| Eamonn Woodcock Associates Limited | Professional & scientific | 2017 |
| East Midlands Care Limited | Health & social care | 2007 |
| East Midlands Water (Direct) Ltd. | Water & waste | 1997 |
| East Midlands Water.Com Limited | Manufacturing | 1998 |
| East Park Investments (Leicester) Limited | Construction | 1983 |
| Eddie Smith & Associates Limited | Wholesale & retail | 2003 |
| Eden Hair Boutique Limited | Other services | 2024 |
| Education for ALL Trust Ltd | Water & waste | 2007 |
| Eeds Limited | Administrative & support | 2006 |
| Effective Development Solutions Limited | Education | 2003 |
| EKL Energy Limited | Energy | 2017 |
| EKL Leisure Limited | Real estate | 2018 |
| Electromech Design and Assembly Limited | Manufacturing | 1980 |
| Elegance Computer Limited | Financial services | 2003 |
| Eletron Limited | Professional & scientific | 1999 |
| ELEV8 IT Ltd. | Information & communication | 2024 |
| Elite Labels (Leicester) Limited | Manufacturing | 2000 |
| Elite Locum Services Limited | Other services | 2007 |
| Elite Thermal Systems Limited | Manufacturing | 1998 |
| Elizabeth a Stone Limited | Administrative & support | 2013 |
| Elmhurst Energy Services Limited | Professional & scientific | 2007 |
| Elmhurst Energy Systems Limited | Administrative & support | 1993 |
| Empress Stores Limited | Wholesale & retail | 2005 |
| EMU Events Limited | Administrative & support | 2006 |
| En-Lighten Technology Ltd | Information & communication | 2008 |
| Entire Maintenance Services Ltd | Administrative & support | 2016 |
| Equality Action Ltd | Other services | 2001 |
| Equity Release Advisor Ltd | Extraterritorial | 2021 |
| Essential Cuts Hair Salon Ltd. | Other services | 2000 |
| Essential Financial Advisers LLP | | 2006 |
| ETA Projects Limited | Professional & scientific | 1996 |
| Etchells Signs Limited | Manufacturing | 2006 |
| Ethitec Limited | Information & communication | 2001 |
| Euler Functions Limited | Financial services | 2020 |
| Euro-Rose Knitwear Ltd | Administrative & support | 2000 |
| Eurofund Services Limited | | 1993 |
| Euromiss Limited | Wholesale & retail | 2002 |
| European Textile Machines Limited | Wholesale & retail | 2002 |
| Eurosigns Holdings Limited | Financial services | 2015 |
| Eurostone Properties Limited | Real estate | 1998 |
| Evans Energy Limited | Professional & scientific | 2002 |
| Evans Heritage Developments Ltd | Construction | 2012 |
| Evcon Limited | Information & communication | 2006 |
| Ever BIN Cleaned Ltd | Other services | 2025 |
| Everards Brewery Limited | Agriculture & fishing | 1936 |
| Ex-Ed Drives and Controls Limited | Manufacturing | 1999 |
| Expeditus Consulting Limited | Professional & scientific | 2003 |
| F. Sherwood & Sons (Shepshed) Limited | Transport & logistics | 1998 |
| F. Shipley & SON Ltd | Construction | 2003 |
| Fabric Crazy Limited | Wholesale & retail | 2024 |
| Fabritex (UK) Limited | Wholesale & retail | 2003 |
| Fabulous Food UN Limited | Transport & logistics | 2006 |
| Fair Farm Hideaway Limited | Hospitality | 2017 |
| Fairway Accessories Limited | Wholesale & retail | 2005 |
| Farecla Products Limited | Manufacturing | 1971 |
| Farsan Ltd | Manufacturing | 1998 |
| Fascinating Properties Limited | Real estate | 2001 |
| Father of 4 Limited | Information & communication | 2026 |
| Faulks & COX Limited | Wholesale & retail | 2002 |
| Fern Carpets Limited | Wholesale & retail | 1992 |
| Festival Players (Loughborough) Limited(The) | Arts & recreation | 1977 |
| Field Medico Legal Reports Limited | Health & social care | 2015 |
| Fielde Engineering Limited | Manufacturing | 1986 |
| Fire Detection & Electrical Services Limited | Construction | 2003 |
| First Property Consultants (UK) Ltd | Real estate | 2005 |
| First Step Photography Limited | Professional & scientific | 2015 |
| First Steps Trading Limited | Wholesale & retail | 2002 |
| Fisher Scientific U.K., Limited | Administrative & support | 1993 |
| Fishers (Leicester) Limited | Other services | 1921 |
| Fitted Solutions Limited | Construction | 2006 |
| Five Lamps House Limited | Households | 2000 |
| Five Turner Street Flats (Management) Limited | Real estate | 1992 |
| FIVEBY5 Industries Limited | Information & communication | 2023 |
| Fletcher & Long Electrical and Property Ltd | Construction | 2018 |
| Flint Engineering Supplies Limited | Wholesale & retail | 2007 |
| Floesis Ltd | Information & communication | 2026 |
| Flood Technologies Limited | Manufacturing | 2012 |
| Flortek Solutions Limited | Construction | 2007 |
| Footprint Software Limited | Information & communication | 2004 |
| Footwear Partnerships Limited | Professional & scientific | 2000 |
| Format Print and Design Limited | Professional & scientific | 1994 |
| Forrest Aviation Services Ltd | Transport & logistics | 2017 |
| Fosse Contracts Limited | Construction | 1984 |
| Fosters Traditional Foods Limited | Wholesale & retail | 2004 |