| Ulysses Engineering Design and Software Ltd | Professional & scientific | 1996 |
| Unity (UK) Limited | Information & communication | 1988 |
| Unity Recovery Service Limited | Transport & logistics | 1981 |
| Universal Grinding Wheel Company Limited | Extraterritorial | 1935 |
| Universal Products (Leicester) Limited | Manufacturing | 1966 |
| V Festa & Sons Haulage Limited | Transport & logistics | 2004 |
| V Richichi Motors Limited | Wholesale & retail | 2003 |
| Vantastic (Leicestershire) Ltd | Wholesale & retail | 2022 |
| Vape Birstall Limited | Administrative & support | 2018 |
| Vape Shepshed Limited | Administrative & support | 2018 |
| Vedic Foods Limited | Extraterritorial | 2006 |
| Venus Legal Services Limited | Professional & scientific | 2018 |
| Venus Packaging Solutions Limited | Administrative & support | 2007 |
| VH Martin Limited | Real estate | 2019 |
| Vibrant Fashions Limited | Manufacturing | 1996 |
| Vicary Plant Spares UK Limited | Wholesale & retail | 2000 |
| Viewtec Limited | Information & communication | 1998 |
| Vince Green Joinery Limited | Wholesale & retail | 1990 |
| Viscus Limited | Information & communication | 1996 |
| Vitax Limited | Manufacturing | 1986 |
| Vmgs Installations Ltd | Transport & logistics | 2017 |
| VU (UK) Ltd | Information & communication | 2007 |
| Vyas Limited | Wholesale & retail | 1989 |
| W & W Engineers Limited | Manufacturing | 2003 |
| W & W Properties Limited | Real estate | 2002 |
| W J Edge & SON Builders Limited | Construction | 2007 |
| W R Customz Ltd | Wholesale & retail | 2025 |
| WAH Ying Ltd | Hospitality | 2006 |
| Walker & SON (Leicester) Limited | Extraterritorial | 1970 |
| Walker's Books Limited | Wholesale & retail | 1977 |
| Walker-Smith Limited | Professional & scientific | 1999 |
| Ward Surveyors Limited | Real estate | 2002 |
| Warwick Thompson Design Limited | Construction | 2004 |
| Waschies UK Ltd | Wholesale & retail | 2025 |
| Watergates Consulting Ltd | Professional & scientific | 2003 |
| Watermead Nurseries Limited | Education | 2003 |
| Wbcc (Thorpe Astley) Ltd | Households | 2003 |
| Webstone Properties Limited | Real estate | 2019 |
| Wellbar Property Investments Limited | Real estate | 2001 |
| Wells & Blackwell Limited | Real estate | 1947 |
| West Apparel UK Holdings Limited | Wholesale & retail | 2021 |
| Westerby Investment Management Limited | Financial services | 1987 |
| Westfield House (Care) Ltd | Health & social care | 1963 |
| Weston, Shipley & Weston Limited | Manufacturing | 1906 |
| Whalebone Publishing Ltd | Professional & scientific | 2022 |
| What Plus Limited | Wholesale & retail | 2007 |
| Whatton Farm Limited | Wholesale & retail | 2018 |
| Wheeler Woodhouse Limited | Information & communication | 2003 |
| Wheelers Luxury Gifts Limited | Wholesale & retail | 1985 |
| Wheelwright Communications Limited | Professional & scientific | 2008 |
| White Line Design Limited | Professional & scientific | 2003 |
| Whitedog Solutions Limited | Other services | 2019 |
| Wilbert Computer Services Limited | Information & communication | 1997 |
| Willesley Business Services Limited | Administrative & support | 2004 |
| Willesley Park Golf Club Limited | Arts & recreation | 1920 |
| Willowbrook World Wide Limited | | 1970 |
| Winbro Group Technologies Limited | Manufacturing | 1992 |
| Winbro Group UK Limited | Professional & scientific | 1999 |
| Witherington & Co Limited | Professional & scientific | 2007 |
| Woodbridge Leicester Ltd. | Real estate | 2004 |
| Woodbury Holdings Limited | Administrative & support | 1999 |
| Word Marketing Limited | Information & communication | 2002 |
| World Centre Limited | Wholesale & retail | 1988 |
| World of Sweets (Hancocks) Limited | Wholesale & retail | 1966 |
| Wreake Properties Limited | Real estate | 2004 |
| Wycliffe Catering Ltd | Hospitality | 2014 |
| X-Ellent | Other services | 2005 |
| Y Leisure Limited | Hospitality | 1999 |
| YAM Sing Restaurant Limited | Hospitality | 2003 |
| Yarnfab International Limited | Wholesale & retail | 2002 |
| Yellowhammer Homes Limited | Construction | 1984 |
| Yellowvale Ltd | Hospitality | 2003 |
| Zephyrin Ltd | Wholesale & retail | 2026 |