| Uppingham Balti Limited | Hospitality | 2019 |
| Uppingham Estates Ltd | Real estate | 2026 |
| Uppingham Furniture Ltd | Wholesale & retail | 2011 |
| Uppingham Launderette Limited | Other services | 2021 |
| Uppingham Manor Ltd | Real estate | 2026 |
| Uppingham Place Management Company Limited | Households | 2022 |
| UPS Shop Limited | Wholesale & retail | 2019 |
| Upsell Events Ltd | Administrative & support | 2018 |
| Upshot Events Limited | Extraterritorial | 2015 |
| Upside Properties Ltd | Real estate | 2022 |
| Upstream Design Solutions Ltd | Professional & scientific | 2024 |
| Uptown House Limited | Real estate | 2024 |
| UQ Securities Ltd | Information & communication | 2014 |
| UQF Resourcing Ltd | Information & communication | 2024 |
| UR Bargains Ltd | Wholesale & retail | 2012 |
| UR Local Store Limited | Wholesale & retail | 2024 |
| UR Stay Holdings Ltd | Financial services | 2018 |
| UR Stay Leicester Limited | Hospitality | 2012 |
| UR Stay Ltd | Hospitality | 2011 |
| Uranus Investments Ltd | Real estate | 2022 |
| URB (Oadby) Ltd | Wholesale & retail | 2021 |
| Urbahype Ltd | Information & communication | 2024 |
| Urbain Homes Ltd | Construction | 2012 |
| Urban (Medicine) Kitchen Ltd | Health & social care | 2015 |
| Urban 154 Limited | Real estate | 2020 |
| Urban Apothecary Limited | Manufacturing | 2005 |
| Urban Building Construct Ltd | Construction | 2024 |
| Urban CBD Ltd | Wholesale & retail | 2018 |
| Urban Cleaning Leicester Limited | Administrative & support | 2025 |
| Urban Concrete Pumping Ltd | Construction | 2019 |
| Urban Deco Ltd | Wholesale & retail | 2024 |
| Urban Elevations Ltd | Real estate | 2024 |
| Urban Equestrian Racing C.I.C. | Agriculture & fishing | 2025 |
| Urban Front Ventures Ltd | Wholesale & retail | 2025 |
| Urban Gill Hair Salon Ltd | Other services | 2026 |
| Urban Graffiti 68 Limited | Manufacturing | 2016 |
| Urban Hortology Ltd | Professional & scientific | 2022 |
| Urban Jatt Ltd | Construction | 2021 |
| Urban Keys Ltd | Real estate | 2021 |
| Urban Lane Limited | Administrative & support | 2025 |
| Urban Legal Limited | Professional & scientific | 2024 |
| Urban Muse Fashion Ltd | Manufacturing | 2025 |
| Urban Poling International Limited | Wholesale & retail | 2024 |
| Urban Products Ltd | Wholesale & retail | 2018 |
| Urban Pubs (Derby) Ltd | Hospitality | 2024 |
| Urban Refurbishments Ltd | Construction | 2025 |
| Urban Tiger Limited | Wholesale & retail | 2011 |
| Urban ZOO Styling Co Limited | Manufacturing | 2022 |
| Urbane Assets Ltd | Construction | 2019 |
| Urbane Hub Ltd | Real estate | 2020 |
| Urbane Management LLP | | 2019 |
| Urbanedge Trade Ltd | Administrative & support | 2026 |
| Urbankey Stays Ltd | Hospitality | 2026 |
| Urbanlink Express Ltd | Transport & logistics | 2025 |
| Urbanproof Limited | Real estate | 1992 |
| Urbansaf Ltd | Wholesale & retail | 2026 |
| Urbansouk Ltd | Wholesale & retail | 2026 |
| Urbanzen Developments Limited | Construction | 2024 |
| Urbello Ltd | Construction | 2022 |
| URG Trade Ltd | Construction | 2022 |
| URG Windows & Doors Ltd | Construction | 2026 |
| Urgent Provider Ltd | Administrative & support | 2023 |
| Urhan Traders Ltd | Wholesale & retail | 2024 |
| Urja Private Ltd | Wholesale & retail | 2025 |
| Uroc Limited | Financial services | 2002 |
| Urooz and Company Ltd | Wholesale & retail | 2025 |
| Urrban Properties Ltd | Hospitality | 2025 |
| Ursan 25 Ltd | Transport & logistics | 2021 |
| Urschel International Limited | Wholesale & retail | 1972 |
| Uruba Restaurant Limited | Hospitality | 2019 |
| Urushop Limited | Wholesale & retail | 2013 |
| Urybeconstruct Ltd | Construction | 2025 |
| US Signs Limited | Professional & scientific | 2020 |
| US2 Property Ltd | Real estate | 2018 |
| Usemango Limited | Information & communication | 2011 |
| Usha Kiran Limited | Information & communication | 2023 |
| Ushrya Limited | Wholesale & retail | 2017 |
| Usines DE Soufre Limited | Extraterritorial | 2009 |
| Usman Optometry Ltd | Professional & scientific | 2021 |
| Usmanexpress Ltd | Wholesale & retail | 2023 |
| Ussen Enterprises Limited | Hospitality | 2018 |
| UST Construction Ltd | Construction | 2019 |
| Ustad Leicester Ltd | Hospitality | 2025 |
| Ustm Limited | Transport & logistics | 2020 |
| Utbh Limited | Construction | 2016 |
| Utech Products Limited | Wholesale & retail | 2014 |
| Uthay Healthcare Limited | Health & social care | 2018 |
| Uthaymeen Shop Ltd | Wholesale & retail | 2020 |
| Utilities Made Simple Ltd | Information & communication | 2016 |
| Utility Energy Brokers Ltd | Administrative & support | 2024 |
| Utility Garage Ltd | Professional & scientific | 2025 |
| Utopia Labs Ltd | Other services | 2020 |
| UTS (Atlas) Limited | Financial services | 2025 |
| UTS Group Holdings Limited | Professional & scientific | 2021 |
| Utsav Banqueting Hall Ltd | Hospitality | 2019 |
| Utter Bedford Ltd | Information & communication | 2019 |
| Utterconnection Conveyancing Limited | Professional & scientific | 2026 |
| Uttoxeter Physiotherapy & Sports Injury Clinic Limited | Professional & scientific | 2013 |
| UVA Product & IT Services Limited | Information & communication | 2024 |
| Uvbrite Ltd | Wholesale & retail | 2007 |