| Edgeware Limited | Wholesale & retail | 2000 |
| Edgewinbodycare Ltd | Wholesale & retail | 2025 |
| Edgmond Greatest Ltd | Hospitality | 2015 |
| Edgreen Fresh Farm Foods | | 2013 |
| EDI MEZ Limited | Administrative & support | 2025 |
| Edi-Cate Ltd | Professional & scientific | 2025 |
| Edinburgh Hospitality Limited | Hospitality | 2024 |
| Edith Care Ltd | Health & social care | 2014 |
| Edith Ziome Care Service Limited | Administrative & support | 2017 |
| Edman Service Ltd | Health & social care | 2022 |
| Edmond & Milburn Limited | Wholesale & retail | 1995 |
| Edmonton Green GB Limited | Wholesale & retail | 2022 |
| Ednomis Consulting Ltd | Information & communication | 2022 |
| EDS Rapid Ltd | Water & waste | 2026 |
| EDS Roofing Supplies (Midlands) Limited | Wholesale & retail | 1993 |
| Edsb Building Services Limited | Other services | 2019 |
| Edsb Finance Limited | Other services | 2018 |
| Edsb Integrated Solutions Limited | Other services | 2017 |
| Edsb Passive Fire Limited | Manufacturing | 2022 |
| Edsb Renewable Energy Limited | Construction | 2022 |
| Edson Harper Limited | Professional & scientific | 2013 |
| EDU Owls Academy CIC | Education | 2022 |
| EDU Vista Global Ltd | Professional & scientific | 2025 |
| Educare Day Nurseries and Nursery Schools Limited | Education | 2007 |
| Educate & Elevate Ltd | Education | 2026 |
| Education by Donovan Ltd | Administrative & support | 2026 |
| Education Development and Support Services Ltd | Education | 2021 |
| Education Engine | Other services | 2021 |
| Education Experience Ltd | Education | 2024 |
| Education Systems Support Limited | Information & communication | 2016 |
| Education Welfare Services (Midlands) Ltd | Education | 2013 |
| Educational AI Innovation Limited | Information & communication | 2025 |
| Educational Link Services Ltd | Education | 2024 |
| Educo Limited | Other services | 2002 |
| Educonvoy International Limited | Professional & scientific | 2025 |
| Eduglobal Ltd | Wholesale & retail | 2025 |
| Eduglobe Limited | Professional & scientific | 2012 |
| Eduglobe Mena Limited | Education | 2024 |
| Edupath Global Ltd | Education | 2025 |
| Edutech IT Systems Ltd | Other services | 2026 |
| Edutech Labs Global Ltd | Information & communication | 2025 |
| Edutech Solutions Ltd | Information & communication | 2006 |
| Eduzone Limited | Administrative & support | 2003 |
| Edvee Clothing Ltd | Manufacturing | 2019 |
| Edward Alexander NW Limited | Financial services | 2016 |
| Edward Court (2003 Management) Limited | Households | 2002 |
| Edward Harte Client Ltd | Professional & scientific | 2025 |
| Edward Hunt Property Group Limited | Real estate | 2022 |
| Edward James Mail Order Limited | Wholesale & retail | 2003 |
| Edward Logistics Ltd | Transport & logistics | 2015 |
| Edward Morris Properties Ltd | Real estate | 2025 |
| Edward Place (Ankerbold Road) Limited | Households | 2021 |
| Edwards Barber Ltd | Other services | 2026 |
| Edwin Cook Machines Tools Limited | Professional & scientific | 1941 |
| EDY2017 Ltd | Administrative & support | 2017 |
| EEG Capital Ltd | Financial services | 2026 |
| EEG Holdings Ltd | Financial services | 2024 |
| Eemia Limited | Wholesale & retail | 2012 |
| Eemotion Ltd | Wholesale & retail | 2021 |
| Eenergy Consultancy Limited | Energy | 1999 |
| Eenergy Insights Limited | Information & communication | 2021 |
| Eeram Ltd | Health & social care | 2017 |
| Eesha Limited | Real estate | 2009 |
| Eeshaanainfotech Ltd | Information & communication | 2025 |
| Eeshaanaittech Ltd | Information & communication | 2025 |
| Eezzy Ltd | Professional & scientific | 2023 |
| EF Health Ltd | Administrative & support | 2023 |
| EF Sparkling Cleaners Ltd | Administrative & support | 2023 |
| Efduk Ltd | Manufacturing | 2024 |
| Efes Express Local Ltd | Wholesale & retail | 2025 |
| Effect Digital Ltd | Information & communication | 2008 |
| Effective Consultants Ltd | Professional & scientific | 2022 |
| Effective Energy Assessors Limited | Professional & scientific | 2023 |
| Effective Energy Group Ltd | Financial services | 2015 |
| Effective Energy Investments Ltd | Extraterritorial | 2017 |
| Effective Energy Ltd | Professional & scientific | 2012 |
| Effective Energy Solutions Ltd | Professional & scientific | 2008 |
| Effective Group Investment Limited | Financial services | 2021 |
| Effective Home Ltd | Wholesale & retail | 2016 |
| Effective Renewables Ltd | Energy | 2017 |
| Effective Support Limited | Health & social care | 2023 |
| Effective Systems (GRP) Limited | Manufacturing | 2010 |
| Effective Utilities Ltd | Professional & scientific | 2016 |
| Efficient Support Services Ltd | Administrative & support | 2025 |
| Efficient Vision Services Ltd | Health & social care | 2025 |
| Efflotreat Limited | Professional & scientific | 2003 |
| EFG Estates Limited | Real estate | 2019 |
| EFG International Ltd | Manufacturing | 2013 |
| Efinance Corp Ltd | Professional & scientific | 2014 |
| Efrench Tuition Online Ltd | Education | 2018 |
| Efsane (Leic) Ltd | Hospitality | 2025 |
| EG Haulage Ltd | Transport & logistics | 2021 |
| EG2S Consulting Ltd | Professional & scientific | 2021 |
| Egaramic Services Limited | Information & communication | 2018 |
| Egatewayz Ltd | Wholesale & retail | 2025 |
| Egbuness Limited | Real estate | 2020 |
| Egdon Logistics Ltd | Transport & logistics | 2014 |
| Egerton Avenue 1970 Limited | Extraterritorial | 2014 |
| Egerton Pitt Ltd | Wholesale & retail | 2025 |
| Eggfree Cakebox Leicester UR Ltd | Wholesale & retail | 2017 |