| Eagna Limited | Professional & scientific | 2019 |
| EAI 555 Ltd | Construction | 2014 |
| EAM Plumbing & Maintenance Limited | Construction | 2023 |
| Eamonn Cassidy Wealth Management Ltd | Financial services | 2007 |
| EAN Ltd | Wholesale & retail | 2018 |
| EAR WAX Removal Leicester Ltd | Health & social care | 2025 |
| Earfinity Limited | Health & social care | 2022 |
| Earl Rivers Ltd | Real estate | 2024 |
| Earl Shilton Cleaners Ltd | Administrative & support | 2025 |
| Earl Shilton Town Cricket & Sports Club,Limited | Arts & recreation | 1921 |
| Earlsheaton Notable Ltd | Wholesale & retail | 2015 |
| Earlston Developments Ltd | Construction | 2020 |
| Early Days Limited | Extraterritorial | 2008 |
| Early Learners' Nursery Schools Limited | Education | 2011 |
| Early Minds Ltd | Financial services | 2021 |
| Early Years Properties Limited | Real estate | 2021 |
| Early Years Quality Counts Limited | Education | 2021 |
| Earnest Investments Ltd | Real estate | 2018 |
| Earnway Limited | Administrative & support | 2025 |
| Earology Leicester Ltd | Health & social care | 2024 |
| Earsential & Derma Care Limited | Health & social care | 2025 |
| Earth Heart Sky Mind Ltd | Other services | 2024 |
| Earthfields Superb Ltd | Wholesale & retail | 2014 |
| Earthsense Group Limited | Financial services | 2021 |
| Earthsense Systems Limited | Professional & scientific | 2016 |
| Earthworks Elite Ltd | Construction | 2025 |
| Eas...Love Coming Home Ltd | Wholesale & retail | 2019 |
| Easa (UK) Ltd | Professional & scientific | 2016 |
| Easco Limited | Real estate | 2022 |
| Easco Properties Limited | Real estate | 2023 |
| Ease at Home Care Limited | Health & social care | 2024 |
| Ease Rides Ltd | Transport & logistics | 2025 |
| Easeway Travel Limited | Administrative & support | 2025 |
| Eash Consulting Ltd | Real estate | 1999 |
| East & West Properties Limited | Real estate | 2016 |
| East 2 West Furniture Company Limited | Wholesale & retail | 2003 |
| East African Voice Association Ltd. | Information & communication | 2008 |
| East Anglian Venues Limited | Hospitality | 2010 |
| East Bond Estates Ltd | Real estate | 2020 |
| East Bond Limited | Real estate | 2019 |
| East Coast Jeeps UK (2019) Ltd | Wholesale & retail | 2019 |
| East Deli Ltd | Wholesale & retail | 2026 |
| East Food & Drink Distribution Ltd | Wholesale & retail | 2018 |
| East Goscote Pharma Limited | Health & social care | 2025 |
| East Goscote Property Ltd | Construction | 2024 |
| East Goscote Roofing Limited | Construction | 2015 |
| East London Properties (UK) Ltd | Real estate | 2014 |
| East Midland Cars Limited | Wholesale & retail | 2022 |
| East Midland Electrical Contractors Ltd | Construction | 2022 |
| East Midland Marathi Association | Other services | 2015 |
| East Midlands Accountancy and Management Services Limited | Professional & scientific | 2000 |
| East Midlands Accountancy Limited | Professional & scientific | 2016 |
| East Midlands Boundary Fencing Ltd | Construction | 2025 |
| East Midlands Brickwork Ltd | Construction | 2025 |
| East Midlands Business Limited | Professional & scientific | 2023 |
| East Midlands Cancer Care Limited | Other services | 2026 |
| East Midlands Clutch Centre Limited | Wholesale & retail | 2018 |
| East Midlands Clutches Ltd | Manufacturing | 2024 |
| East Midlands College Ltd | Administrative & support | 2025 |
| East Midlands Community Housing Ltd | Construction | 2024 |
| East Midlands Construction Limited | Construction | 2023 |
| East Midlands Couriers Ltd | Transport & logistics | 2019 |
| East Midlands Electronics LLP | | 2010 |
| East Midlands Facilities Management Limited | Construction | 2025 |
| East Midlands Fencing Limited | Construction | 1995 |
| East Midlands Homes Limited | Construction | 2020 |
| East Midlands Industrial Doors Ltd | Construction | 2022 |
| East Midlands Landscape (Contractors) Limited | Administrative & support | 2006 |
| East Midlands Landscaping Ltd | Administrative & support | 1987 |
| East Midlands Leisure Group Limited | Wholesale & retail | 2016 |
| East Midlands Metals (Derby) Limited | Wholesale & retail | 2021 |
| East Midlands Orthodontics Labs Limited | Manufacturing | 2013 |
| East Midlands Orthodontics Limited | Administrative & support | 2012 |
| East Midlands Pharma Limited | Wholesale & retail | 2005 |
| East Midlands Public Affairs Ltd | Professional & scientific | 2024 |
| East Midlands Regional Venture Capital Fund NO. 1 L.P. | | 2002 |
| East Midlands Screens Limited | Wholesale & retail | 2013 |
| East Midlands Sealants Ltd | Construction | 2026 |
| East Midlands Security & Fire Limited | Professional & scientific | 2017 |
| East Midlands Technology Ltd | Information & communication | 2023 |
| East Midlands Trading Limited | Wholesale & retail | 2011 |
| East Midlands Vans Ltd | Wholesale & retail | 2010 |
| East Mids Air Conditioning Ltd | Administrative & support | 2019 |
| East Mids Oven Cleaning Ltd | Administrative & support | 2022 |
| East Mids Van Centre Ltd | Wholesale & retail | 2025 |
| East Park Grocers Ltd | Wholesale & retail | 2026 |
| East Park Investments Ltd | Real estate | 2019 |
| East Park Newcastle Ltd | Real estate | 2026 |
| East Park Taxi Limited | Transport & logistics | 2018 |
| East Priors Ltd | Administrative & support | 2018 |
| East Rksalles Ltd | Wholesale & retail | 2024 |
| East Street Lanes Limited | Arts & recreation | 2018 |
| East to West Flavour Limited | Hospitality | 2024 |
| East View Farms Ltd | Agriculture & fishing | 2016 |
| East West Community Centre Limited | Health & social care | 2012 |
| East-Mid Services Ltd | Administrative & support | 2021 |
| EAST2WEST97 Ltd | Manufacturing | 2022 |
| Eastacombe Haulage Ltd | Transport & logistics | 2014 |
| Eastbourne Advantage Ltd | Wholesale & retail | 2015 |
| Eastbourne House Ltd | Health & social care | 2015 |