| Dobeco Limited | Extraterritorial | 2025 |
| Dobhai Stores Narborough Ltd | Hospitality | 2016 |
| Dobry Sklep Limited | Wholesale & retail | 2015 |
| Dobson's Memorials Limited | Other services | 1997 |
| DOC SAM Transport Limited | Wholesale & retail | 2024 |
| DOC Waqf Limited | Real estate | 2022 |
| Docent Advisory Ltd | Professional & scientific | 2026 |
| Docherty's (Leicester) Ltd | Wholesale & retail | 2021 |
| Dock & Door Install Ltd | Construction | 2019 |
| Dockerill (Plant Hire) Ltd | Construction | 2009 |
| Docket Live Limited | Health & social care | 2011 |
| Docking Investments Limited | Professional & scientific | 2020 |
| Doctor AP Ltd | Health & social care | 2019 |
| Doctor Cares Laboratories Limited | Health & social care | 2025 |
| Doctor H.N. Shukla and Company Limited | Health & social care | 2015 |
| Doctor Herb Ltd | Wholesale & retail | 2018 |
| Doctor Locums Ltd | Health & social care | 2023 |
| Doctor Properties Ltd | Real estate | 2018 |
| Doctor SKP Ltd | Health & social care | 2022 |
| Doctor Solar Ltd | Construction | 2026 |
| Doctor Visit Limited | Health & social care | 2018 |
| Doctors on Wheels Limited | Health & social care | 2007 |
| Doctors Professional Services Limited | Health & social care | 2011 |
| Docucheck Ltd | Administrative & support | 2023 |
| Document Centric Solutions Ltd. | Information & communication | 2008 |
| Documentary Media Centre Limited | Professional & scientific | 2020 |
| Dodds Solicitors LLP | | 2011 |
| Dodo Recruitment Ltd | Administrative & support | 2023 |
| Dodona Research Limited | Information & communication | 1999 |
| Does Most Things Limited | Information & communication | 2014 |
| Dog EAT Dog Limited | Other services | 2017 |
| Dog Washer Ltd | Other services | 2026 |
| Dogar Rice Limited | Wholesale & retail | 2023 |
| DOGAR68 Ltd | Health & social care | 2026 |
| Dogged Developments Limited | Financial services | 2026 |
| Doggett Properties Limited | Real estate | 2022 |
| Doggy Daycare @ the Willows (Dunton Bassett) Ltd | Other services | 2024 |
| Doggy Daycare @ the Willows Ltd | Other services | 2021 |
| Doherty Surveyors Ltd | Real estate | 2017 |
| Doing More Print Ltd | Manufacturing | 2023 |
| Dokan Limited | Wholesale & retail | 2023 |
| Doksy Limited | Wholesale & retail | 2017 |
| Dolashad Devine Ltd Ltd | Real estate | 2025 |
| Dolce Vita Harmony Ltd | Wholesale & retail | 2025 |
| Dolcemassageone Limited | Professional & scientific | 2025 |
| Dolci (Bradford) Limited | Wholesale & retail | 2019 |
| Dolci (Liverpool) Limited | Hospitality | 2020 |
| Dolcienne Ltd | Wholesale & retail | 2019 |
| Dollies Cookies Limited | Manufacturing | 2017 |
| Dolls Care Ltd | Health & social care | 2025 |
| Dolphin Creations Ltd | Information & communication | 2024 |
| Dolvicta Desserts Limited | Hospitality | 2025 |
| DOM Nicole Absolute Fitness Limited | Arts & recreation | 2021 |
| DOM Payne Ltd | Administrative & support | 2016 |
| Domenare Properties Limited | Real estate | 1969 |
| Domet Ltd | Information & communication | 2025 |
| Domiciliary Care Services (UK) Limited | Health & social care | 2004 |
| Dominance Design Ltd | Wholesale & retail | 2025 |
| Dominic Sloane Aesthetics Ltd | Other services | 2023 |
| Dominion Body Repairs Ltd | Wholesale & retail | 2016 |
| Dominion Faith Church Limited | Other services | 2021 |
| Domos Shop Limited | Hospitality | 2026 |
| Domus Bardon Ltd | Real estate | 2012 |
| Domus Care Property Management Ltd | Real estate | 2025 |
| Domus Lxxxviii Ltd | Real estate | 2025 |
| Domus PVT Limited | Real estate | 2012 |
| DON Carlo's Takeaway Limited | Hospitality | 2021 |
| DON Carlo's Trading Ltd | Hospitality | 2020 |
| DON Julio & Sons Ltd | Transport & logistics | 2016 |
| Donald Byford Limited | Agriculture & fishing | 1973 |
| Donald's Chippy Ltd | Hospitality | 2023 |
| Doncaster High SUB Ltd | Hospitality | 2023 |
| Doncaster Road Dental Practice Limited | Health & social care | 2009 |
| Doncaster Road Garage Limited | Manufacturing | 2016 |
| Donceninga Ltd | Transport & logistics | 2018 |
| Donco Ltd | Wholesale & retail | 2025 |
| Dondi Holdings Ltd | Wholesale & retail | 2022 |
| Doner Express Limited | Hospitality | 2012 |
| Donersty Express Ltd | Hospitality | 2026 |
| Donersty Ltd | Hospitality | 2024 |
| Donersty to Go Ltd | Hospitality | 2026 |
| Dongyi Sourcing UK Limited | Manufacturing | 2020 |
| Donlan D Limited | Health & social care | 2025 |
| Donner Kitchen Limited | Hospitality | 2026 |
| Donnpals Ltd | Manufacturing | 2025 |
| Doon Spice Limited | Hospitality | 2023 |
| Doops Hair Ltd | Education | 2024 |
| Door & Loading Bay Services Limited | Construction | 2015 |
| Door 6 Holdings Limited | Professional & scientific | 2019 |
| Door 6 Limited | Professional & scientific | 2005 |
| Door to Door FIX Limited | Manufacturing | 2025 |
| Door Valley Ltd | Wholesale & retail | 2019 |
| Doors With Design Limited | Extraterritorial | 1992 |
| Dopatrain Ltd | Wholesale & retail | 2024 |
| Doppler Arts Ltd | Education | 2024 |
| Doppler Studio Ltd | Information & communication | 2022 |
| Doproconsulting Ltd | Professional & scientific | 2020 |
| Doralise Limited | Wholesale & retail | 2025 |
| Doran Plant Hire Ltd | Construction | 2013 |
| Doran Projects Ltd | Construction | 2022 |