| Design Agency Four Ltd | Professional & scientific | 2015 |
| Design Architecture London Ltd | Extraterritorial | 2014 |
| Design by Kiwi Ltd | Professional & scientific | 2018 |
| Design by MYS Ltd | Professional & scientific | 2018 |
| Design Leicester Ltd | Professional & scientific | 2023 |
| Design Locker Limited | Manufacturing | 2010 |
| Design ME Happy Ltd | Professional & scientific | 2020 |
| Design MEP Group Holdings Limited | Financial services | 2025 |
| Design MEP Holdings Ltd | Financial services | 2019 |
| Design MEP Investments Limited | Real estate | 2022 |
| Design MEP Limited | Professional & scientific | 2017 |
| Design Ninja Ltd | Professional & scientific | 2015 |
| Design Only Gardens Ltd | Administrative & support | 2023 |
| Design Patch Ltd | Administrative & support | 2012 |
| Design Services Consultant Limited | Professional & scientific | 2014 |
| Design Square Limited | Professional & scientific | 2008 |
| Design Studio Architects Limited | Professional & scientific | 2013 |
| Design Technical UK Ltd | Professional & scientific | 2026 |
| Design Technologies UK Ltd | Professional & scientific | 2008 |
| Design Three Sixty Limited | Real estate | 2023 |
| DESIGN68 Limited | Manufacturing | 2026 |
| Designeering Associates Ltd | Professional & scientific | 2010 |
| Designer Bathrooms (Leicester) Limited | Wholesale & retail | 2005 |
| Designer by Chance Ltd | Wholesale & retail | 2018 |
| Designer Clearance Brands Ltd | Wholesale & retail | 2026 |
| Designer Daisies Limited | Wholesale & retail | 2014 |
| Designer Kids Club Ltd | Wholesale & retail | 2024 |
| Designer Living Group Ltd | Professional & scientific | 2023 |
| Designer Metals Limited | Manufacturing | 2004 |
| Designer Mortgages Limited | Financial services | 2003 |
| Designer Wealth Ltd | Financial services | 2023 |
| Designer Workshop Limited | Manufacturing | 2015 |
| Desinica Ltd | Wholesale & retail | 2025 |
| Desire Kitchens Ltd | Manufacturing | 2020 |
| Desk Top Supplies Limited | Administrative & support | 2000 |
| Desmond (UK) Ltd | Transport & logistics | 2013 |
| Desor Associates Ltd | Professional & scientific | 2009 |
| Desor Consultancy Ltd | Professional & scientific | 2006 |
| Despierta Ltd | Health & social care | 2024 |
| Desquared Marketing Limited | Administrative & support | 2021 |
| Dessert House Earl Shilton Ltd | Hospitality | 2025 |
| Dessertedbros Ltd | Hospitality | 2026 |
| Desserts Brand UK Limited | Wholesale & retail | 2022 |
| Dessertsloaded Leicester Ltd | Hospitality | 2025 |
| Destiny Business Services (UK) Ltd | Professional & scientific | 2015 |
| Destinychi Ltd | Health & social care | 2021 |
| Destinydrive Logistics Ltd | Transport & logistics | 2026 |
| Destro Tech Limited | Information & communication | 2023 |
| Detailar Ltd | Wholesale & retail | 2024 |
| Detailor Group Ltd | Administrative & support | 2026 |
| Determination Creates Success Ltd | Wholesale & retail | 2025 |
| Detox Cosmetics Limited | Wholesale & retail | 2019 |
| Detroit Pizza Islington Ltd | Hospitality | 2023 |
| Deuce House Right to Manage Company Limited | Households | 2019 |
| DEV by DEV Ltd | Information & communication | 2023 |
| DEV Electrics Ltd | Construction | 2024 |
| DEV Fashions Ltd | Manufacturing | 2018 |
| DEV International Trading Limited | Wholesale & retail | 2025 |
| DEV Motors Ltd | Wholesale & retail | 2026 |
| DEV Realisations (2019) Limited | Construction | 1959 |
| DEV Sols Limited | Real estate | 2022 |
| DEV Transport Services Ltd | Transport & logistics | 2025 |
| DEV Vyas Limited | Wholesale & retail | 2003 |
| DEV55S Limited | Real estate | 2024 |
| Devanjo Limited | Real estate | 2017 |
| Devanshi Ltd | Extraterritorial | 2009 |
| Devdhruv Holdings Limited | Real estate | 2026 |
| Developed Edge Limited | Professional & scientific | 2012 |
| Developers Evolved Ltd | Administrative & support | 2009 |
| Developing Your Potential Recruitment Ltd | Administrative & support | 2011 |
| Development and Land Ltd | Real estate | 2021 |
| Development Joinery Ltd | Manufacturing | 2025 |
| Devesh (Leicester) Ltd | Wholesale & retail | 2023 |
| Devham Investments | Financial services | 2025 |
| Devi Consultants Ltd | Financial services | 2019 |
| Devil Maids Limited | Other services | 2023 |
| Devils Own Clothing Limited | Extraterritorial | 2013 |
| Devils Own Coffee Ltd | Wholesale & retail | 2025 |
| Devils Own Piercing Limited | Other services | 2022 |
| Devils Own Tattoo Studios Limited | Other services | 2011 |
| Devilz Bar Ltd | Manufacturing | 2025 |
| Devinco Ltd | Information & communication | 2018 |
| Devine Installations Ltd | Construction | 2026 |
| Devixa Labs Ltd | Information & communication | 2022 |
| Devji Solutions Limited | Administrative & support | 2012 |
| Devraj (UK) Limited | Health & social care | 2014 |
| Devrup Ltd | Wholesale & retail | 2025 |
| Devshi Investments Ltd | Real estate | 2021 |
| Devstree IT Solutions Limited | Information & communication | 2024 |
| DEW Drop Foods Ltd | Wholesale & retail | 2015 |
| Dewshi Ltd | Transport & logistics | 2021 |
| Dewston Endeavours Ltd | Transport & logistics | 2014 |
| Dewy Delight Ltd | Wholesale & retail | 2024 |
| Dexb Limited | Information & communication | 2023 |
| Dexterford Limited | Real estate | 1982 |
| Dexterjohnw Ltd | Wholesale & retail | 2025 |
| Dexterous Healthcare Services (Dhsl) Ltd | Health & social care | 2024 |
| Dextrous.Net Limited | Information & communication | 2001 |
| Dezign & Print Ltd | Manufacturing | 2021 |
| Dezign Management Ltd | Professional & scientific | 2011 |