| Stubbington Professional Services Ltd | Health & social care | 2021 |
| Stubru Limited | Wholesale & retail | 2013 |
| Stuch Ventures Limited | Transport & logistics | 2025 |
| Student Barrister Limited | Information & communication | 2023 |
| Student Minds | Health & social care | 2011 |
| Student Properties HQ (Hyde Park) Ltd | Real estate | 2018 |
| Studio 35 at Westgate Ltd | Other services | 2025 |
| Studio 42 Group Limited | Information & communication | 2024 |
| Studio 5 Tattoo Ltd | Other services | 2026 |
| Studio 82 Beauty Hub Ltd | Other services | 2024 |
| Studio 93 Ltd | Professional & scientific | 2021 |
| Studio Elephant Ltd | Professional & scientific | 2020 |
| Studio Fortune Ltd | Professional & scientific | 2026 |
| Studio Frazer Ltd | Professional & scientific | 2023 |
| Studio HG Ltd | Professional & scientific | 2026 |
| Studio Holloway Ltd | Professional & scientific | 2020 |
| Studio Input Ltd | Information & communication | 2025 |
| Studio Kaioti Limited | Information & communication | 2018 |
| Studio KS1 Ltd | Information & communication | 2018 |
| Studio Makal Ltd | Professional & scientific | 2022 |
| Studio Marrs Ltd | Professional & scientific | 2018 |
| Studio Nefce Limited | Information & communication | 2022 |
| Studio NO.1 Pilates Ltd | Other services | 2026 |
| Studio Play Nice Ltd | Professional & scientific | 2025 |
| Studio Pond Games Limited | Information & communication | 2023 |
| Studio South North Limited | Professional & scientific | 2026 |
| Studio Sudo Ltd | Professional & scientific | 2018 |
| Studio TCT Limited | Information & communication | 2025 |
| Studio TDH Creative Ltd | Professional & scientific | 2023 |
| Studio This Limited | Professional & scientific | 2023 |
| Studio TOM, Dick & Harry Ltd | Professional & scientific | 2015 |
| Studio Urban Limited | Financial services | 2020 |
| Studio Wald Ltd. | Wholesale & retail | 2021 |
| Studio Xinxin Ltd | Professional & scientific | 2025 |
| Studio Z G Ltd | Manufacturing | 2024 |
| STUDIO12 Barbershop Ltd | Other services | 2022 |
| Studiojye Ltd | Other services | 2018 |
| Studiopad Ltd | Professional & scientific | 2024 |
| Studiosahn Ltd | Information & communication | 2019 |
| Studioyeti Ltd | Professional & scientific | 2024 |
| Studland Homes Ltd | Construction | 2021 |
| Study Bridge Consultant Limited | Education | 2025 |
| Study Shed Global Consultants Ltd | Administrative & support | 2026 |
| Stuf Creative Ltd | Real estate | 2018 |
| Stuff 4 Offices Limited | Administrative & support | 2000 |
| Stuntrocket Ltd | Information & communication | 2015 |
| Sturgeon Consulting Ltd | Administrative & support | 2017 |
| Sturton Consulting Limited | Information & communication | 2019 |
| Stuzzi Leeds Limited | Hospitality | 2018 |
| Stuzzi Limited | Hospitality | 2014 |
| Styebank Apartments Limited | Real estate | 2008 |
| Style QNZ Limited | Wholesale & retail | 2025 |
| Style Sight Ltd | Wholesale & retail | 2023 |
| Style Studio Leeds Ltd | Other services | 2025 |
| Style YOU Pretty Ltd | Other services | 2022 |
| Styledbyzk Limited | Manufacturing | 2025 |
| Styleforgeai Ltd | Information & communication | 2026 |
| Styles & Wood Group Limited | Professional & scientific | 2005 |
| Stylish Treats Ltd | Wholesale & retail | 2025 |
| Styrin Motors Limited | Wholesale & retail | 2002 |
| Su-Recruit Ltd | Administrative & support | 2017 |
| SUB Feast Limited | Hospitality | 2019 |
| SUB Hub Care Group Ltd | Health & social care | 2025 |
| SUB Melt Ltd | Hospitality | 2025 |
| Sub-Link Solutions Ltd | Construction | 2017 |
| Suba Capital Holding Ltd | Information & communication | 2023 |
| Suba Capital UK Limited | Information & communication | 2025 |
| Subby Connect Ltd | Construction | 2026 |
| Subfit Limited | Construction | 2022 |
| Subfood Partners Ltd | Hospitality | 2020 |
| Subhan Flooring & Furnishing Limited | Wholesale & retail | 2025 |
| Subhan Halal Meat Shop Ltd | Wholesale & retail | 2023 |
| Subhan Rugs Limited | Wholesale & retail | 2020 |
| Sublime Health Limited | Health & social care | 2017 |
| Sublime Home Installations Ltd | Construction | 2010 |
| Sublime Short Stays Ltd | Hospitality | 2017 |
| Sublina UK Ltd | Wholesale & retail | 2026 |
| Subpixel Ltd | Professional & scientific | 2014 |
| Subsea Design (UK) Limited | Administrative & support | 2005 |
| Substructure (Piling) Limited | Construction | 2009 |
| Substructure Limited | Construction | 2006 |
| Subterra Mechanics Limited | Wholesale & retail | 1995 |
| Subvisionsmusic Limited | Arts & recreation | 2025 |
| Sucasa Enterprise Limited | Health & social care | 2022 |
| Succeed With Fulfilment Ltd | Professional & scientific | 2020 |
| Success Planet Ltd | Wholesale & retail | 2020 |
| Successful Events Limited | Administrative & support | 2014 |
| Successors to Wilson and Company Barnsley,Limited | Professional & scientific | 1938 |
| Succex World Co Ltd | Hospitality | 2013 |
| Such Finance Systems Limited | Information & communication | 2014 |
| Such Gozzby Ltd | Wholesale & retail | 2025 |
| SUD Companies Limited | Administrative & support | 2012 |
| Suda's Taste Ltd | Wholesale & retail | 2019 |
| Sudanese Daju Community, CIC | Professional & scientific | 2019 |
| Sudanese House Restaurant Leeds Ltd | Hospitality | 2025 |
| Sudanese Junior Doctors Association Limited | Health & social care | 2018 |
| Sudden Movements Limited | Arts & recreation | 2011 |
| Suds Cleaners Ltd | Other services | 2025 |
| SUE Brayshaw Ltd | Wholesale & retail | 2022 |
| SUE Graham Limited | Wholesale & retail | 1988 |