| Sprinkle of Sparkle Ltd | Wholesale & retail | 2025 |
| Sprinkle World Ltd | Hospitality | 2023 |
| Sprinkwell Mill Management Company Limited | Households | 2002 |
| Sprint Finishing Limited | Manufacturing | 1988 |
| Sprite Solar Ltd | Construction | 2025 |
| Spro Technologies Ltd | Information & communication | 2013 |
| Sprout Coaching Ltd | Professional & scientific | 2020 |
| Sprs Investments Limited | Real estate | 2025 |
| Spruce Products Limited | Administrative & support | 2021 |
| Spruce Workwear Ltd | Manufacturing | 2016 |
| Spry UK Consulting Ltd | Professional & scientific | 2024 |
| SPS Food Limited | Hospitality | 2021 |
| SPS Smith's Property Services Ltd | Construction | 2025 |
| Spsj Properties Ltd | Real estate | 2024 |
| Spsp Care Ltd | Health & social care | 2019 |
| SPT Analytics Limited | Information & communication | 2009 |
| SPT Enterprises Limited | Hospitality | 1988 |
| SPT Leeds Ltd | Wholesale & retail | 2023 |
| SPT Uniforms Ltd | Manufacturing | 2008 |
| Spudd Gaming Ltd | Arts & recreation | 2025 |
| Spuddys and Wraps Ltd | Hospitality | 2026 |
| Spuds and Bro's Limited | Hospitality | 2021 |
| SPV STC1 Limited | Construction | 2026 |
| SPV STC2 Limited | Construction | 2026 |
| SPV STC3 Limited | Construction | 2026 |
| SPW North Group Ltd | Hospitality | 2023 |
| Spyraldna Limited | Other services | 2021 |
| Spyrou Estates Ltd | Real estate | 2025 |
| SQ Healthcare Ltd | Public administration | 2024 |
| Sqestates Limited | Real estate | 2025 |
| Sqew Limited | Hospitality | 2018 |
| SQU1DGES Ltd | Wholesale & retail | 2025 |
| Squad Leeds Limited | Real estate | 2021 |
| Squadmin Ltd | Information & communication | 2022 |
| Squadron IT Services Limited | Information & communication | 2023 |
| Square About Leeds Limited | Hospitality | 2024 |
| Square About Potternewton Ltd | Hospitality | 2026 |
| Square Assets Ltd | Real estate | 2020 |
| Square Formations Ltd | Construction | 2020 |
| Square Landscaping Ltd | Administrative & support | 2011 |
| Square Marketing Limited | Other services | 2016 |
| Square Mile Freelance Limited | Real estate | 2010 |
| Square PEG Events Limited | Arts & recreation | 2015 |
| Square Pizza House Limited | Hospitality | 2020 |
| Square Place Limited | Real estate | 2015 |
| Square-I Ltd | Administrative & support | 2005 |
| Squarecubed Ltd | Information & communication | 2014 |
| Squared Away Bookkeeping Services Limited | Professional & scientific | 2013 |
| Squared Circle Group Limited | Professional & scientific | 2019 |
| Squarepeg Buses Ltd | Transport & logistics | 2015 |
| Squareset Ltd | Professional & scientific | 2015 |
| Squash Media & Marketing Limited | Arts & recreation | 2020 |
| Squash Media Limited | Arts & recreation | 2025 |
| Squash United Foundation | Health & social care | 2016 |
| Squeaky Clean (Northern) Limited | Administrative & support | 2006 |
| Squeeky Clean Cars Limited | Wholesale & retail | 2024 |
| Squid Island Lord Food Ltd | Wholesale & retail | 2024 |
| Squid Software Ltd | Information & communication | 2022 |
| Squire Company Limited | Extraterritorial | 1997 |
| Squire Hairdressing Limited | Other services | 2015 |
| Squire Nutrition Ltd | Manufacturing | 2026 |
| Squire W.Swift Limited | | 1941 |
| Squosh (Franchising) Limited | Other services | 2024 |
| SR City Stays Ltd | Wholesale & retail | 2015 |
| SR Financial Services Ltd | Financial services | 2020 |
| SR Installations (Yorkshire) Ltd | Construction | 2011 |
| SR Joinery and Building Ltd | Construction | 2018 |
| SR Kippax Ltd | Hospitality | 2024 |
| SR Painting & Decorating Ltd | Construction | 2012 |
| SR Partners Limited | Professional & scientific | 2006 |
| SR Properties (Yorkshire) Ltd | Real estate | 2023 |
| SR Property Services Ltd | Real estate | 2023 |
| SR Services (Yorkshire) Ltd | Hospitality | 2019 |
| SR Site Services Ltd | Construction | 2007 |
| SR Sood Ltd | Health & social care | 2010 |
| SR Stress Engineering Limited | Other services | 2000 |
| SR Surgical Services Ltd | Health & social care | 2023 |
| Sram Consulting Ltd | Information & communication | 2010 |
| Srao Solutions Ltd | Information & communication | 2019 |
| SRC Consultancy Limited | Information & communication | 2011 |
| Src-Search Limited | Administrative & support | 2019 |
| Srch Media Ltd | Professional & scientific | 2020 |
| Srcl Limited | Administrative & support | 1996 |
| SRE Jubilee Listerhills Limited | Real estate | 2021 |
| Sree Soft Ltd | Information & communication | 2015 |
| SRG Creative Ltd | Professional & scientific | 2020 |
| Srguk Limited | Wholesale & retail | 2018 |
| SRH Cars (Leeds) Ltd | Wholesale & retail | 2018 |
| SRI Chakra Limited | Information & communication | 2024 |
| SRI Chakra Software Solutions Ltd | Information & communication | 2012 |
| SRI Enterprises Limited | Professional & scientific | 2020 |
| SRI Investment Holdings Limited | Professional & scientific | 2018 |
| SRI NON Thai Kitchen Ltd | Hospitality | 2021 |
| SRI SAI Lakshmi Ltd | Information & communication | 2015 |
| SRI SRI SRI Hanumath Kali Vara Prasada Babu Spiritual Center CIC | Other services | 2024 |
| Sribalaji Infotech Limited | Information & communication | 2011 |
| Srilakshmi Tech Limited | Information & communication | 2022 |
| Srinon Leeds Ltd | Hospitality | 2025 |
| Sriyan Properties Limited | Real estate | 2022 |
| SRJ Restaurant Ltd | Hospitality | 2025 |