| Shack House Company Ltd | Construction | 2019 |
| Shackleton Recruitment Group Ltd | Administrative & support | 2024 |
| Shackletons Group Limited | Financial services | 2017 |
| Shackletons Limited | Manufacturing | 2000 |
| Shad Phone Clinic Ltd | Wholesale & retail | 2024 |
| Shades Canvas Ltd | Administrative & support | 2010 |
| Shades Event Support Ltd | Administrative & support | 2024 |
| Shadespan Limited | Construction | 2023 |
| Shadow Elox Limited | Professional & scientific | 2024 |
| Shadow Transport Limited | Transport & logistics | 2021 |
| Shadowline MTB Ltd | Administrative & support | 2026 |
| Shadows Paranormal Ltd | Arts & recreation | 2022 |
| Shadowtrak Ltd | Administrative & support | 2026 |
| Shadwell Chapel Management Company Limited | Real estate | 2015 |
| Shadwell Childcare Limited | Education | 2006 |
| Shadwell Computer Services Limited | Information & communication | 2014 |
| Shadwell Consulting Ltd | Health & social care | 2022 |
| Shadwell Dental Care Limited | Health & social care | 2007 |
| Shadwell Developments Limited | Construction | 2004 |
| Shadwell Independent Library Limited | Arts & recreation | 2012 |
| Shadwell Mead Management Company (1) Limited | Households | 1983 |
| Shadwell Mead Management Company (2) Limited | Households | 1986 |
| Shadwell Optical Ltd | Health & social care | 2011 |
| Shaek Limited | Professional & scientific | 2015 |
| Shafiqs Properties Limited | Real estate | 2024 |
| Shaftesbury Motors Limited | Real estate | 1933 |
| Shaftsbury Fisheries 2.0 Ltd | Hospitality | 2026 |
| Shaftsbury Fisheries Limited | Hospitality | 2018 |
| Shah Property Developments Ltd | Construction | 2020 |
| Shah Property Management Ltd | Real estate | 2006 |
| Shah Property Mgmt Ltd | Households | 2026 |
| Shah Security Guarding SSG Ltd | Administrative & support | 2026 |
| Shah Strategies Limited | Real estate | 2023 |
| Shah Travel (Hajj & Umra) Ltd | Administrative & support | 2005 |
| Shah-Uk Limited | Transport & logistics | 2025 |
| Shahd (Leeds) Limited | Wholesale & retail | 2020 |
| Shaheen Shah Trading Ltd | Wholesale & retail | 2026 |
| Shaheer Petroleum Ltd | Wholesale & retail | 2018 |
| Shahi Healthcare Limited | Health & social care | 2025 |
| Shahid FX Ltd | Administrative & support | 2025 |
| Shahin Mendy Ltd | Administrative & support | 2026 |
| Shahinoor Properties Limited | Real estate | 2022 |
| Shahleta Ltd | Real estate | 2025 |
| Shahnila Khan Limited | Other services | 2020 |
| Shahpar Properties Ltd | Real estate | 2024 |
| Shahzad Yousaf Ltd | Health & social care | 2013 |
| Shahzada Maily Builders Limited | Construction | 2023 |
| Shahzam Developments Limited | Other services | 2017 |
| Shahzimal Ltd | Wholesale & retail | 2025 |
| Shai NAN Kebab Ltd | Hospitality | 2024 |
| Shails Estate Limited | Real estate | 2025 |
| Shak's Vehicle Services Limited | Transport & logistics | 2022 |
| Shake the Cake Limited | Hospitality | 2023 |
| Shakeeh Ltd | Wholesale & retail | 2025 |
| Shakeology Ltd | Extraterritorial | 2022 |
| Shakespeare Advisory Limited | Professional & scientific | 2025 |
| Shakil Trading Limited | Other services | 2025 |
| Shalaw & Sons Investment Ltd | Real estate | 2024 |
| Shaleem World Ltd | Wholesale & retail | 2021 |
| Shalex Education Ltd | Education | 2023 |
| Shalex Properties Ltd | Real estate | 2024 |
| Shalimar (Leeds) Ltd | Hospitality | 2024 |
| Shaliya One Limited | Real estate | 2023 |
| Shallowdale Limited | Real estate | 1972 |
| Shalom Interpreting & Translation Ltd | Professional & scientific | 2023 |
| Sham News Ltd | Wholesale & retail | 2026 |
| Sham Residential Limited | Real estate | 2025 |
| Shamani Skincare Ltd | Other services | 2025 |
| Shambles Holding Limited | Financial services | 2016 |
| Shamicare Limited | Health & social care | 2019 |
| Shammahz Limited | Information & communication | 2012 |
| Shampan Group Ltd | Real estate | 2015 |
| Shampooch Parlour Ltd | Wholesale & retail | 2018 |
| Shamrock Home Help Limited | Health & social care | 2014 |
| Shamrock Meals at Home Ltd | Manufacturing | 2025 |
| Shamruck Limited | Health & social care | 2025 |
| Shams ADI Ltd | Education | 2024 |
| Shamzeco Limited | Wholesale & retail | 2024 |
| Shanco Civil Engineering Ltd | Construction | 2003 |
| Shanco Contracts Limited | Construction | 2013 |
| Shanco Group Limited | Financial services | 2015 |
| Shanco Holdings Limited | Financial services | 2020 |
| Shanco Property Group Limited | Real estate | 2023 |
| Shane Durrant Music Ltd | Arts & recreation | 2022 |
| Shanelia Luxe Hair Limited | Other services | 2026 |
| Shangrileeds Ltd | Administrative & support | 2014 |
| Shankland Barraclough Ltd | Real estate | 2023 |
| Shannydar Ltd | Transport & logistics | 2020 |
| Shans Online Limited | Wholesale & retail | 2022 |
| Shans Premier Supermarket Ltd | Wholesale & retail | 2023 |
| Shanti Estates Unlimited, Ltd | Real estate | 2021 |
| Shantia International Limited | Real estate | 2020 |
| Shantona Women's & Family Services Ltd. | Extraterritorial | 1998 |
| Shany Builders Ltd | Construction | 2021 |
| Shapa Store Limited | Wholesale & retail | 2025 |
| Shape & Base Limited | Construction | 2023 |
| Shape Club Ltd | Other services | 2020 |
| Shape Global Ltd | Information & communication | 2019 |
| Shape Tomorrow Limited | Professional & scientific | 2021 |
| Shapeshifters Leeds Ltd | Administrative & support | 2016 |