| Sapphire Buildings (Bradford) Ltd | Real estate | 2017 |
| Sapphire Services (UK) Ltd | Wholesale & retail | 2014 |
| Sapphire Sky Holdings Limited | Financial services | 2020 |
| Sapphire Utility Solutions Limited | Water & waste | 2013 |
| Sapphirewing Limited | Health & social care | 2023 |
| Sapple Engineering Ltd | Professional & scientific | 2025 |
| Sapurvi Ltd | Information & communication | 2014 |
| Saqib Travels Ltd | Transport & logistics | 2023 |
| Saqr Hepworth Ltd | Real estate | 2024 |
| Sara ALI Limited | Transport & logistics | 2026 |
| Sara Korn Counselling Limited | Health & social care | 2021 |
| Sara Louise Ltd | Other services | 2022 |
| Sara M London Ltd | Wholesale & retail | 2024 |
| Sara Pugh Ltd | Wholesale & retail | 2020 |
| Sara Walker Independent Eyewear Agency Ltd | Wholesale & retail | 2024 |
| Sara's Beauty Limited | Other services | 2007 |
| Sarade Healthcare Limited | Administrative & support | 2017 |
| Sarah Crowley Limited | Professional & scientific | 2025 |
| Sarah Dewhirst Limited | Financial services | 2022 |
| Sarah Dougal IFA Ltd | Administrative & support | 2016 |
| Sarah Ellis Rehabilitation Services Ltd | Health & social care | 2025 |
| Sarah France Ltd | Health & social care | 2023 |
| Sarah Gordon Studio Ltd | Professional & scientific | 2020 |
| Sarah Hitchings Ltd | Arts & recreation | 2023 |
| Sarah Homes Limited | Construction | 2022 |
| Sarah Leeds Ltd | Wholesale & retail | 2019 |
| Sarah Love Limited | Information & communication | 2025 |
| Sarah Mcdermott Ltd | Professional & scientific | 2022 |
| Sarah Merrick Limited | Real estate | 2021 |
| Sarah Motors Limited | Wholesale & retail | 2020 |
| Sarah Wass Consulting Limited | Professional & scientific | 2019 |
| Saras Technology Limited | Manufacturing | 1998 |
| Sarason Limited | Education | 2013 |
| Sarawak Limited | Professional & scientific | 2017 |
| Sarayah & Co Ltd | Wholesale & retail | 2017 |
| Sarbast Limited | Wholesale & retail | 2026 |
| Sardar Telee Food Store Ltd | Wholesale & retail | 2024 |
| Sardara Properties Ltd | Real estate | 2025 |
| Sardarjee Ltd | Hospitality | 2020 |
| Sarela Investments Ltd | Financial services | 2017 |
| Sarelco Ltd | Professional & scientific | 2020 |
| Sariel Heseltine Ltd | Information & communication | 2017 |
| Saros Cleaning Limited | Administrative & support | 2024 |
| Sarras Street Food Ltd | Hospitality | 2024 |
| Sars Logistics Limited | Transport & logistics | 2019 |
| Sarsfield Building Developments Limited | Construction | 2023 |
| Saruz Ltd | Real estate | 2022 |
| Sarvamangal Limited | Wholesale & retail | 2025 |
| Sarvaya Ltd | Wholesale & retail | 2026 |
| SAS (Leeds) Ltd | Real estate | 2022 |
| SAS Installations Limited | Other services | 2022 |
| SAS Plasterers Limited | Construction | 2006 |
| Sasa Limited | Administrative & support | 2003 |
| Sasan Express Ltd | Wholesale & retail | 2025 |
| Sasareappiah Ltd | Transport & logistics | 2021 |
| Saschdan Ltd | Hospitality | 2026 |
| Sash Interiors Limited | Manufacturing | 2013 |
| Sasha Brow Bar Ltd. | Wholesale & retail | 2015 |
| Sasha Leeds Limited | Other services | 2015 |
| Sasha Luxury Limited | Wholesale & retail | 2020 |
| Sashaboutique Limited | Wholesale & retail | 2022 |
| Sashank Ltd | Hospitality | 2014 |
| Saskia Mews Management Company Limited | Households | 2016 |
| Satchwake Limited | Real estate | 2003 |
| Satellite Plate Production (Litho) Limited | | 1975 |
| Satellite Plate Production(Printing)Limited | | 1971 |
| Satish Kohli and Rekha Kohli T/A SK Investments Leeds Limited | Construction | 2020 |
| Satsense Limited | Professional & scientific | 2017 |
| Saturn Direct Limited | Professional & scientific | 1998 |
| Satya Roofing Solutions Ltd | Construction | 2025 |
| Sauce People Limited | Administrative & support | 2019 |
| Saudha, Society of Poetry and Indian Music | Arts & recreation | 2012 |
| Saul Clothing Ltd | Wholesale & retail | 2019 |
| Saul Studio Ltd | Professional & scientific | 2019 |
| Saur (UK) Limited | Professional & scientific | 1986 |
| Saur Services (Glasgow) Limited | Water & waste | 1998 |
| Saurabh Limited | Professional & scientific | 2024 |
| Sausome Creations Ltd | Manufacturing | 2022 |
| Sava Leeds Ltd | Hospitality | 2022 |
| Savage Holdings (London) Ltd | Financial services | 2026 |
| Savage Kidz Ltd | Wholesale & retail | 2024 |
| Savanna Distribution Ltd | Wholesale & retail | 2020 |
| Savanna Holidays Ltd | Hospitality | 2025 |
| Savannah Pharmaceuticals Limited | Wholesale & retail | 2025 |
| Savannah Property Solutions Limited | Professional & scientific | 2016 |
| Savant Distribution Limited | Health & social care | 1996 |
| Save 4 Energy Limited | Professional & scientific | 2023 |
| Save Face Limited | Information & communication | 2013 |
| Savera Healthcare Ltd | Health & social care | 2024 |
| Saveya Hair Ltd | Other services | 2018 |
| Saveya Homes Enterprise Ltd | Real estate | 2025 |
| Savi Cleaning Products (North) Ltd | Other services | 2014 |
| Savi Developments & Maintenance Limited | Construction | 2021 |
| Savi Developments Limited | Real estate | 2021 |
| Saviano Food Import Ltd | Hospitality | 2011 |
| Savile Road Garage Ltd | Wholesale & retail | 2019 |
| Saville & Woods Ltd. | Administrative & support | 1975 |
| Savings Champion.Co.Uk Limited | Information & communication | 2011 |
| Savious Ltd | Wholesale & retail | 2024 |
| Savison Ltd | Information & communication | 2010 |