| Saltd and Batterd Limited | Hospitality | 2025 |
| Salts Studios Limited | Information & communication | 2025 |
| Salty WOK Limited | Hospitality | 2025 |
| Saluka Properties Limited | Real estate | 2017 |
| Salus Padel (Bradford) Limited | Arts & recreation | 2025 |
| Salus Padel Communities CIC | Education | 2026 |
| Salus Padel Limited | Arts & recreation | 2025 |
| Salus Studios Ltd | Information & communication | 2026 |
| Salutary Ventures Limited | Real estate | 2026 |
| Salutohabeco Ltd | Health & social care | 2015 |
| Salva Legacy Ltd | Professional & scientific | 2025 |
| Salvage the Slay Ltd | Wholesale & retail | 2025 |
| Salvati Commercial Ltd | Real estate | 2025 |
| Salvo’S Restaurant Ltd | Hospitality | 2026 |
| Salwan Al-Biatty Locum Limited | Health & social care | 2018 |
| SAM & JO Properties Ltd | Real estate | 2021 |
| SAM Alexander Properties Ltd | Real estate | 2020 |
| SAM and Sons Property's Management Limited | Real estate | 2019 |
| SAM Bhagat Consulting Ltd | Administrative & support | 2018 |
| SAM Civil Engineering Ltd | Construction | 2026 |
| SAM Consultants London Limited | Professional & scientific | 2012 |
| SAM D Property Ltd | Real estate | 2024 |
| SAM Dickinson Performance Ltd | Arts & recreation | 2026 |
| SAM Diner Ltd | Hospitality | 2019 |
| SAM E Drums Ltd | Arts & recreation | 2025 |
| SAM Euro Ltd | Wholesale & retail | 2022 |
| SAM Joseph Music Ltd | Information & communication | 2018 |
| SAM Long Construction Limited | Construction | 2015 |
| SAM Smart Cleans Ltd | Administrative & support | 2025 |
| Sam&Boys Ltd | Hospitality | 2023 |
| Sam's Cafe (Keightley) Ltd | Hospitality | 2024 |
| Sam's GIN Bar Ltd | Hospitality | 2019 |
| Sam-Pro Prestige Educational Consultant Limited | Education | 2025 |
| Samaa Babel Ltd | Professional & scientific | 2019 |
| Samad (Yorkshire) Limited | Hospitality | 2019 |
| Samaita Properties Ltd | Real estate | 2019 |
| Saman's Property Ltd | Real estate | 2024 |
| Samara Asset Management Ltd | Real estate | 2016 |
| Samara Group Ltd | Financial services | 2019 |
| Samara Properties Limited | Hospitality | 2016 |
| Samazing Ltd | Health & social care | 2014 |
| Samb Property Development Ltd | Households | 2023 |
| Samba Allstars Ltd | Arts & recreation | 2023 |
| Sambuca (Leeds) Ltd | Hospitality | 2019 |
| Sambuca Armley Ltd | Hospitality | 2022 |
| Sambuca Lounge Ltd | Hospitality | 2016 |
| Sambuca Morley Ltd | Hospitality | 2023 |
| Samco Global Ltd | Wholesale & retail | 2021 |
| Samcom Investments Limited | Extraterritorial | 2014 |
| Same Day Nationwide Limited | Transport & logistics | 2025 |
| Same Day Solutions Limited | Transport & logistics | 2022 |
| Samedayteeth Limited | Health & social care | 2013 |
| Sameer K Limited | Administrative & support | 2015 |
| Samek Enterprises Limited | Wholesale & retail | 2020 |
| Samem Ltd | Other services | 2019 |
| Sameva Property Limited | Real estate | 2004 |
| Sami Bhai Ltd | Wholesale & retail | 2024 |
| Samicrs Limited | Transport & logistics | 2022 |
| Samii Painting Limited | Manufacturing | 2025 |
| Samin Investments Ltd | Real estate | 2022 |
| Samira’S Bubble Ltd | Real estate | 2024 |
| Samling Ltd | Real estate | 2025 |
| Sammon Building Contractors Ltd | Construction | 2013 |
| Sammon Properties Ltd | Real estate | 2016 |
| Sammy Casey-Marten Training Limited | Education | 2017 |
| Samn DEV Ltd | Information & communication | 2024 |
| Samngqa Limited | Health & social care | 2016 |
| SAMOSA4U Ltd | Manufacturing | 2017 |
| Sampharm Ltd | Health & social care | 2021 |
| Sample Connect Limited | Transport & logistics | 2013 |
| Samplephonics Ltd | Information & communication | 2008 |
| Sampson Management Services Limited | Professional & scientific | 2023 |
| Samson Maintenance Plans Limited | Other services | 2011 |
| Samson's Transport Services Ltd | Transport & logistics | 2021 |
| Samsoomi Limited | Wholesale & retail | 2025 |
| Samtek Limited | Extraterritorial | 2001 |
| Samtron Properties Limited | Real estate | 2021 |
| Samuel Alexander Consulting Ltd | Administrative & support | 2018 |
| Samuel Brown Ltd | Professional & scientific | 2023 |
| Samuel C Smaldon Ltd | Administrative & support | 2012 |
| Samuel Capitanu Ltd | Construction | 2023 |
| Samuel Catalin Ltd | Transport & logistics | 2025 |
| Samuel Grant (Holdings) Ltd | Professional & scientific | 2014 |
| Samuel Grant (Leeds) Limited | Wholesale & retail | 1992 |
| Samuel Grant Group Limited | Professional & scientific | 1921 |
| Samuel Hope Jewellery Limited | Extraterritorial | 2004 |
| Samuel MC Limited | Transport & logistics | 2025 |
| Samulak Ltd | Transport & logistics | 2013 |
| Samways Business Support Services Limited | Professional & scientific | 2017 |
| Samy Trans Limited | Administrative & support | 2025 |
| SAMYSMY95 Limited | Transport & logistics | 2025 |
| Samāveśa School of Yoga Limited | Education | 2024 |
| Sam’S Cure Ltd | Other services | 2025 |
| Sana Gamar Ltd | Health & social care | 2026 |
| Sana Khan Ltd | Professional & scientific | 2021 |
| Sana Mente Care Ltd | Health & social care | 2024 |
| Sanabosh Ltd | Real estate | 2022 |
| Sanacare Limited | Health & social care | 2019 |
| Sanati Homes Limited | Real estate | 2025 |
| Sancerre (Yorkshire) Ltd | Hospitality | 2023 |