| Sabre Consultants Limited | Administrative & support | 2013 |
| Sabre Distribution Ltd | Wholesale & retail | 2014 |
| Sabrewing Limited | Health & social care | 2017 |
| Sabri Property Group Ltd | Real estate | 2025 |
| Sabtim Limited | Health & social care | 2016 |
| Sabura Club Limited | Hospitality | 2023 |
| Sabura Limited | Wholesale & retail | 2019 |
| Sabzee Ltd | Wholesale & retail | 2020 |
| SAC Leisure Ltd | Wholesale & retail | 2026 |
| Sacco Mann Limited | Administrative & support | 1996 |
| Sacco Mann Recruitment Group Limited | Financial services | 2026 |
| Sacco Mann Recruitment Holdings Limited | Financial services | 2019 |
| Sachina Hire Ltd | Other services | 2019 |
| Sacred Geometry Limited | Professional & scientific | 2019 |
| SAD Entertainment (Yorkshire) Ltd | Hospitality | 2024 |
| Sadalage Enterprises Ltd | Health & social care | 2024 |
| Sadaqat Limited | Health & social care | 2009 |
| Saddington Limited | Hospitality | 2024 |
| Saddiq Developments Ltd | Real estate | 2018 |
| Saddiq Group Ltd | Wholesale & retail | 2020 |
| Saddique Khan Properties Ltd | Real estate | 2024 |
| Saddle Hill Properties Ltd | Real estate | 2017 |
| Sadf Express Limited | Transport & logistics | 2022 |
| Sadhana Properties Limited | Real estate | 2021 |
| Sadhi UK Ltd | Hospitality | 2025 |
| Sadia Arshad Limited | Real estate | 2026 |
| Sadiq & Ghazan Ltd | Real estate | 2017 |
| Sadler Consultancy Ltd | Professional & scientific | 2016 |
| Sadra Painting Limited | Construction | 2020 |
| Saeed Joiner Ltd | Construction | 2024 |
| Saengjan Food Ltd | Hospitality | 2024 |
| SAF & Zahid Riaz Properties Ltd | Real estate | 2021 |
| SAF Associates (UK) Limited | Health & social care | 2010 |
| SAF Holdings Limited | Real estate | 2017 |
| SAF Property Solutions Ltd | Construction | 2020 |
| Safa Catering Supplies Ltd | Wholesale & retail | 2023 |
| Safa Express Limited | Transport & logistics | 2024 |
| Safa Horizon Ltd | Information & communication | 2018 |
| Safa Properties Leeds Ltd | Real estate | 2024 |
| Safaa Medical Services Limited | Health & social care | 2019 |
| Safari Art House Ltd | Arts & recreation | 2023 |
| Safari Cubs Ltd | Health & social care | 2018 |
| Safari Systems Limited | Education | 2016 |
| Safe & Sound Vehicle Systems Limited | Manufacturing | 2012 |
| Safe 'N' Secure (Windows & Doors) Limited | Construction | 2003 |
| Safe and Secure IT Solutions Limited | Information & communication | 2018 |
| Safe Electrics Contracting Ltd | Construction | 2024 |
| Safe Flames (Leeds) Limited | Construction | 2021 |
| Safe for Launch Limited | Professional & scientific | 2022 |
| Safe Hands Homecare (Yorkshire) Ltd | Health & social care | 2022 |
| Safe Motors Limited | Wholesale & retail | 2025 |
| Safe Nest Housing & Support CIC | Hospitality | 2026 |
| Safe Space Housing Limited | Hospitality | 2021 |
| Safe Space Installations Ltd | Construction | 2023 |
| Safe Space Labs Ltd | Education | 2023 |
| Safe Storage Leeds Ltd | Transport & logistics | 2026 |
| Safe Track Assets Limited | Information & communication | 2021 |
| Safeguard Armour Ltd | Wholesale & retail | 2010 |
| Safeguard HSE Consultancy Group Ltd | Professional & scientific | 2025 |
| Safeguard Software Limited | Information & communication | 2015 |
| Safehands Care Ltd | Health & social care | 2025 |
| Safehaven Companions CIC | Health & social care | 2025 |
| Safehavenfire Ltd | Wholesale & retail | 2025 |
| Safekey Property Group Ltd | Hospitality | 2025 |
| Safemore Risk Solutions Ltd | Professional & scientific | 2022 |
| Safeplace Services Ltd | Hospitality | 2024 |
| Safer Houses Ltd. | Real estate | 2022 |
| Safer Lives Ltd | Professional & scientific | 2018 |
| Saferguarding Security Services Limited | Administrative & support | 2023 |
| Safethrift Co-Operative Society C.I.C. | Financial services | 2026 |
| Safety Information Systems Limited | Information & communication | 1991 |
| Safety Inspections Group Ltd | Construction | 2020 |
| Safety Recoveries & Servicing Ltd | Wholesale & retail | 2023 |
| Safety UK (SW) Limited | Professional & scientific | 2014 |
| Safety UK Group Ltd | Financial services | 2023 |
| Safetydocs Ltd | Information & communication | 2023 |
| SAFETYSIGNS4YOU Ltd | Extraterritorial | 2021 |
| Safevape Ltd | Water & waste | 2025 |
| Saffag Properties Ltd | Real estate | 2019 |
| Saffag Ventures LLP | | 2024 |
| Saffprop Limited | Real estate | 2020 |
| Saffron (Garforth) Ltd | Hospitality | 2018 |
| Saffron Leeds Ltd | Hospitality | 2021 |
| Saffron Spice Acomb Ltd | Hospitality | 2021 |
| Safi IS Family UK Ltd | Wholesale & retail | 2024 |
| Safia Mustafa Holdings Ltd | Financial services | 2005 |
| SAFINA91 Ltd | Professional & scientific | 2020 |
| Safproper Limited | Manufacturing | 2024 |
| Saftronics Group Limited | Professional & scientific | 2010 |
| Saf’S Pizzas Ltd | Hospitality | 2025 |
| Sagacity Consulting Ltd | Professional & scientific | 2014 |
| Sage for ALL Ltd | Professional & scientific | 2022 |
| Sage Forensics Limited | Professional & scientific | 2025 |
| Sage Guitar Academy Ltd | Education | 2023 |
| Sage Mart Ltd | Wholesale & retail | 2024 |
| Sage Property Ltd | Real estate | 2020 |
| Sagedale Consulting Limited | Information & communication | 2021 |
| Sagen Electrical Ltd | Construction | 2024 |
| Sageview Care Ltd | Administrative & support | 2025 |
| Sagitta Properties Ltd | Real estate | 2021 |