| Reframe Hair Studio Ltd | Other services | 2023 |
| Refresh Recovery Limited | Financial services | 2007 |
| Refreshjet Pressure Washing Ltd | Administrative & support | 2023 |
| Refreshsmile Ltd | Wholesale & retail | 2024 |
| Refrigerant GAS Supplies Ltd | Wholesale & retail | 2018 |
| Refrigeration and Cooling System Experts Ltd | Manufacturing | 2021 |
| Reg.Hill Plumbers Limited | Extraterritorial | 2017 |
| Regain Pain Management Ltd | Health & social care | 2022 |
| Regain Performance Management Ltd | Other services | 2024 |
| Regal Court (Beverley) Management Company Limited | Households | 2001 |
| Regal FAD Group Ltd | Manufacturing | 2025 |
| Regal Fire and Security Ltd | Administrative & support | 2018 |
| Regal Item Limited | Wholesale & retail | 2026 |
| Regal Property Solutions Ltd | Real estate | 2024 |
| Regal Sapphire Investments Limited | Financial services | 2025 |
| Regal Skincare Ltd | Wholesale & retail | 2017 |
| Regal Sweets and Treats Ltd | Manufacturing | 2014 |
| Regal Wholesale Electrical Limited | | 1952 |
| Regan Park Developments Ltd | Construction | 2025 |
| Regarding Recruitment Limited | Administrative & support | 2009 |
| Regen Alwoodley Limited | Health & social care | 2021 |
| Regen Durham Limited | Health & social care | 2021 |
| Regen Hub | Education | 2021 |
| Regen Hull Limited | Health & social care | 2021 |
| Regen Physio Ltd | Health & social care | 2019 |
| Regen Physio Rotherham Limited | Health & social care | 2020 |
| Regen Tickhill Limited | Health & social care | 2021 |
| Regenco (Winchburgh) Limited | Construction | 2007 |
| Regency Court (Leeds) Limited | Households | 1964 |
| Regency Gold Exchange Limited | Wholesale & retail | 2025 |
| Regency Online Shopping Limited | Other services | 2019 |
| Regency Place (Tockwith) Management Company Limited | Real estate | 2022 |
| Regency Smart Shop Ltd. | Wholesale & retail | 2019 |
| Regenerate Asset Management Ltd | Financial services | 2019 |
| Regenerate Holdings Ltd | Financial services | 2022 |
| Regenerate Innovations Ltd | Professional & scientific | 2024 |
| Regenerate Outcomes Ltd. | Professional & scientific | 2020 |
| Regenerate Ventures Limited | Professional & scientific | 2021 |
| Regeneration Physiotherapy Limited | Health & social care | 2012 |
| Regenerative Agroforestry (UK) Ltd | Financial services | 2026 |
| Regenerative Pharma Consulting Ltd | Professional & scientific | 2017 |
| Regent House Property Maintenance Limited | Construction | 2014 |
| Regent Lion Properties Limited | Professional & scientific | 1956 |
| Regent Manor Ltd | Real estate | 2025 |
| Regent Oak Recruitment Ltd | Administrative & support | 2019 |
| Regent One Estates Ltd | Construction | 2014 |
| Regent Property Limited | Construction | 2008 |
| Regent Rise International Limited | Wholesale & retail | 2026 |
| Regents Green (Grassmoor) Management Company Limited | Households | 2016 |
| Regiis Ceramics (Residential) Limited | Construction | 2025 |
| Regiis Ceramics Ltd | Construction | 2021 |
| Reginald Remedy Limited | Wholesale & retail | 2025 |
| Regional Business Services Limited | Professional & scientific | 1995 |
| Regional Media Services Limited | Administrative & support | 2009 |
| Regional Media Services Properties Ltd | Financial services | 2025 |
| Regional Paints Limited | Wholesale & retail | 2004 |
| Regrace City Limited | Hospitality | 2025 |
| Regrace City Restaurant Ltd | Hospitality | 2025 |
| Regyment Ltd | Arts & recreation | 2025 |
| Regza Store Ltd | Wholesale & retail | 2018 |
| Reha Solutions Limited | Information & communication | 2025 |
| Rehabwell 360 Physiotherapy and Healthcare Ltd | Health & social care | 2025 |
| Rehman Fast Food Ltd | Hospitality | 2026 |
| Rehman Michael (Accountants) Limited | Professional & scientific | 2011 |
| Rehman Michael (Holdings) Limited | Professional & scientific | 2011 |
| Rehmantrade Ltd | Financial services | 2025 |
| Rehoboth International Holdings Ltd | Professional & scientific | 2020 |
| Rehumanise CIC | Health & social care | 2025 |
| Reid and Stone Roofing Limited | Construction | 2020 |
| Reiden Property Ltd | Construction | 2025 |
| Reign Healthcare Ltd | Health & social care | 2022 |
| Reignites Ltd | Information & communication | 2026 |
| Reigns Consultancy Ltd | Transport & logistics | 2016 |
| Reimagining General Practice Apms Services Ltd | Health & social care | 2019 |
| Reimagining General Practice Health Support Services Ltd | Professional & scientific | 2017 |
| Rein Oaks Ltd | Water & waste | 2025 |
| Reinfratek Limited | Information & communication | 2015 |
| Reinwoods Limited | Real estate | 2023 |
| Reish Ltd | Real estate | 2023 |
| Rejoice Care Ltd | Health & social care | 2018 |
| Rejuvaskin & Laser Clinic Ltd | Professional & scientific | 2015 |
| Rejuvenate by SAM Limited | Administrative & support | 2023 |
| Rejuvenate Productions Limited | Professional & scientific | 2003 |
| Rejuvencare Ltd | Wholesale & retail | 2023 |
| REK International Logistics and Trading Limited | Wholesale & retail | 2025 |
| Rekka Ltd | Education | 2025 |
| Reksio Limited | Wholesale & retail | 2023 |
| Relate Care Solutions Ltd | Health & social care | 2018 |
| Relate Education Consultancy Ltd | Education | 2024 |
| Relational Children's Social Work Services (NRS) Ltd | Health & social care | 2023 |
| Relative Connections Limited | Administrative & support | 2009 |
| Relax Holiday Lets Limited | Hospitality | 2025 |
| Relax Trip Ltd | Transport & logistics | 2024 |
| Relaxaco Sleigh Beds Ltd | Manufacturing | 2019 |
| Rele Limited | Education | 2020 |
| Rele London Ltd | Wholesale & retail | 2023 |
| Released Ltd | Information & communication | 2015 |
| Relevance Catering Limited | Hospitality | 2021 |
| Relevance Consulting Limited | Information & communication | 2018 |
| Reliabell Fire & Security Limited | Construction | 2015 |