| Esatto Limited | Manufacturing | 2016 |
| ESC Property Limited | Real estate | 2026 |
| Escape Games Leeds Ltd | Arts & recreation | 2021 |
| Escape Tots Ltd | Administrative & support | 2022 |
| Escapeworld Ltd | Wholesale & retail | 2024 |
| Escapism Academy Ltd | Professional & scientific | 2023 |
| Escapism Bar Group Limited | Hospitality | 2018 |
| Escastle Properties Ltd | Real estate | 2017 |
| Escroge Drive Ltd | Transport & logistics | 2025 |
| ESD Alpha Limited | Construction | 2025 |
| ESD Holiday Lets Ltd | Real estate | 2026 |
| ESD Surveying Limited | Professional & scientific | 2014 |
| ESE Bar DE Tapas Ltd | Hospitality | 2025 |
| ESE Tafri Collections Limited | Wholesale & retail | 2025 |
| Esega Limited | Health & social care | 2023 |
| Esehjr Limited | Health & social care | 2014 |
| ESG Mindset Ltd | Administrative & support | 2024 |
| Esgate Properties Limited | Real estate | 2019 |
| Eshaal Trading UK Ltd | Wholesale & retail | 2024 |
| Eshald Mansions (Management Company) Limited | Real estate | 2008 |
| Eshams Radiology Ltd | Health & social care | 2019 |
| Eshlin Homes Ltd | Real estate | 2017 |
| Eshlin Investments Ltd | Other services | 2022 |
| Eshopster Ltd | Wholesale & retail | 2023 |
| Eshton Castlevale (Catterick) Limited | Construction | 2020 |
| Eshton Castlevale (Northallerton) Limited | Real estate | 2020 |
| Eshton Developments (Stockton) Ltd | Construction | 2006 |
| Eshton Developments Ltd | Real estate | 2014 |
| Eshton Ltd | Real estate | 2001 |
| Eshton Menstone Ltd | Real estate | 2014 |
| Eshton New Ridge Ltd | Construction | 2006 |
| Eshton Oakfield Ltd | Real estate | 2009 |
| Eshton Property Development Ltd | Real estate | 2003 |
| Eshton Thirty One Limited | Construction | 2006 |
| ESI Water Limited | Professional & scientific | 2018 |
| Esi's Bites Ltd | Hospitality | 2022 |
| Esilam Ltd | Health & social care | 2022 |
| Esiri Health Care Limited | Health & social care | 2015 |
| ESJ Medical Ltd | Health & social care | 2015 |
| Esjs 1 Limited | Manufacturing | 1925 |
| Eskdale Holdings Ltd | Real estate | 2021 |
| Eskimo Joe's Limited | Manufacturing | 2014 |
| ESL (Yorkshire) Limited | Professional & scientific | 2021 |
| Eslington Limited | Manufacturing | 2021 |
| ESM Trans Ltd | Transport & logistics | 2018 |
| Esobi Limited | Health & social care | 2022 |
| Esoft Designs Ltd | Information & communication | 2019 |
| Esol Online Ltd | Education | 2022 |
| Espalier Property Project 008 Ltd | Real estate | 1998 |
| Espec Safety and Compliance Ltd | Professional & scientific | 2025 |
| Esplanade Director Limited | Professional & scientific | 2007 |
| Esplanade Group (Scarborough) International Limited | Financial services | 2010 |
| Esplanade Property Management Company (Scarborough) Ltd | Real estate | 2026 |
| Esplanade Secretarial Services Limited | Professional & scientific | 2007 |
| Espresso Plus Limited | Extraterritorial | 2002 |
| ESR Properties (Yorkshire) Ltd | Real estate | 2024 |
| ESR Talent Limited | Information & communication | 2023 |
| ESS - Security Limited | Construction | 2003 |
| ESS Bidco Limited | Financial services | 2023 |
| ESS Holdings Limited | Financial services | 2006 |
| ESS Installations PLC | Professional & scientific | 1993 |
| ESS Merger Limited | Extraterritorial | 2013 |
| ESS Properties Limited | Real estate | 2012 |
| ESS Textiles Limited | Manufacturing | 1955 |
| Essa Compny UK Ltd | Manufacturing | 2024 |
| Essanden Goods Limited | Wholesale & retail | 2025 |
| Essay Osman Logistics Limited | Transport & logistics | 2026 |
| Esse Property Group Limited | Real estate | 2019 |
| Essence Instruments Ltd | Professional & scientific | 2024 |
| Essence Kitchens and Bathrooms Ltd | Construction | 2025 |
| Essence Neurodevelopment Ltd | Professional & scientific | 2024 |
| Essencerealm Limited | Real estate | 1998 |
| Essential Consulting Group Limited | Professional & scientific | 2005 |
| Essential Planet Ltd | Wholesale & retail | 2023 |
| Essential Recruitment Limited | Administrative & support | 2014 |
| Essential Trading Limited | Wholesale & retail | 2025 |
| Essington Memorial Gardens Holdings Limited | Financial services | 2025 |
| Essington Memorial Gardens Limited | Real estate | 2023 |
| Esso Energy UK Limited | Construction | 2023 |
| EST Dambou ET Frère Ltd | Wholesale & retail | 2021 |
| EST Display Ltd | Information & communication | 2010 |
| Establishment of Medical Psychiatry Essex Limited | Health & social care | 2002 |
| Estadia Group Ltd | Information & communication | 2026 |
| Estate Agents by Rebecca Ltd | Administrative & support | 2023 |
| Estate Management (7) Limited | Households | 1993 |
| Estate Management 28 Limited | Households | 1997 |
| Estate Management 29 Limited | Professional & scientific | 1997 |
| Estate Management 57 Limited | Households | 1998 |
| Estate Management 68 Limited | Other services | 1999 |
| Estate Management 86 Limited | Professional & scientific | 2000 |
| Estates Management Services Limited | Real estate | 2018 |
| Estates Marlborough Management Co Limited | Households | 2022 |
| Estay Limited | Wholesale & retail | 1993 |
| Este Medical Group (Leeds) Ltd | Other services | 2017 |
| Este Medical Group Management Ltd | Health & social care | 2021 |
| Esteem Media Ltd | Information & communication | 2018 |
| Esteem Plus Ltd | Health & social care | 2020 |
| Estelle Thompson Photography Ltd | Professional & scientific | 2023 |
| Estery Care Limited | Health & social care | 2025 |
| Estey Healthcare Limited | Health & social care | 2015 |