| Dragonfly Electronics Ltd | Wholesale & retail | 2012 |
| Dragonfly Home Interiors Limited | Construction | 2024 |
| Dragonfly Initiatives Limited | Real estate | 2024 |
| Dragonfly Investment Properties Limited | Real estate | 2025 |
| Dragonfly Lancs Ltd | Manufacturing | 2024 |
| Dragonfly Management Limited | Information & communication | 2004 |
| Dragonfly Online Ltd | Wholesale & retail | 2019 |
| Drai Media Ltd | Information & communication | 2021 |
| Draincare Holdings Limited | Financial services | 2022 |
| Drains First Limited | Water & waste | 2006 |
| Drake & Warters Limited | | 1933 |
| Drake Wealth Management Ltd | Financial services | 2018 |
| Drakes Plumbing & Heating Services Ltd | Construction | 2020 |
| Drannamahmad Ltd | Health & social care | 2023 |
| Dransfield Limited | Arts & recreation | 2000 |
| Dransfield Novelty Company Limited | Arts & recreation | 1946 |
| Drau Physiotherapy Ltd | Health & social care | 2023 |
| Draw (UK) Limited | Professional & scientific | 2013 |
| Draw the Line Permanent Cosmetics Limited | Other services | 2009 |
| Drawcivil Ltd | Professional & scientific | 2025 |
| Drawing Baud Solutions Ltd | Information & communication | 2023 |
| DRB Property Care Ltd | Construction | 2024 |
| Drca Group Ltd | Water & waste | 2024 |
| DRD Fast Buildings Limited | Construction | 2025 |
| Dreadnaut Ltd | Information & communication | 2021 |
| Dreadnought Films (BP) Limited | Information & communication | 2022 |
| Dream Abode Limited | Real estate | 2026 |
| Dream Big Digital Ltd | Other services | 2019 |
| Dream Carers Ltd | Health & social care | 2023 |
| Dream House (Leeds) Ltd | Real estate | 2018 |
| Dream International BED Ltd | Manufacturing | 2025 |
| Dream Machine Digital Ltd | Information & communication | 2020 |
| Dream Maintenance Limited | Construction | 2022 |
| Dream Properties & Assets Ltd | Financial services | 2024 |
| Dream Reality Ltd | Information & communication | 2020 |
| Dream Reality Media Ltd | Arts & recreation | 2024 |
| Dreamhouse Decorators Ltd | Construction | 2025 |
| Dreamkiln Ltd | Information & communication | 2024 |
| Dreamweaver Brands Ltd | Other services | 2016 |
| Dreamz Cutz Ltd | Other services | 2024 |
| Dreem Limited | Health & social care | 2018 |
| Dreier Digital Limited | Information & communication | 2018 |
| Dresler Smith Limited | Administrative & support | 2003 |
| Dress UP Leeds Ltd | Manufacturing | 2019 |
| Dress UP Ltd | Wholesale & retail | 2013 |
| Drew Property Ltd | Real estate | 2022 |
| Drhouserenovation Ltd | Construction | 2023 |
| Dri-Base Ltd | Construction | 2022 |
| Driffield Brothers Limited | Agriculture & fishing | 1963 |
| Drift Mist Limited | Manufacturing | 2022 |
| Drift Stop Limited | Arts & recreation | 2022 |
| Drighlington Dolphins Ltd | Education | 2020 |
| Drillray Properties Limited | Professional & scientific | 1988 |
| Drilltec (Northern) Limited | Wholesale & retail | 1998 |
| Drink Nova Ltd | Wholesale & retail | 2025 |
| Drinking Well Limited | Wholesale & retail | 2025 |
| Drinks of Manchester Limited | Manufacturing | 2015 |
| Drinks on Wheels Ltd | Wholesale & retail | 2024 |
| Drinq Soft Limited | Information & communication | 2024 |
| Dritzl Ltd | Professional & scientific | 2012 |
| Drive Automotive Ltd | Wholesale & retail | 2020 |
| Drive Away Cars Ltd | Wholesale & retail | 2024 |
| Drive Digital Media Ltd | Information & communication | 2020 |
| Drive Nation Ltd | Other services | 2018 |
| Drive Performance Limited | Wholesale & retail | 2021 |
| Drive Time Ltd | Real estate | 2013 |
| Drive Xperience Ltd | Education | 2024 |
| Drivelife Group Ltd | Financial services | 2025 |
| Drivelife Ltd | Wholesale & retail | 2020 |
| Driven Private Hire Ltd | Transport & logistics | 2025 |
| Driven Vehicle Rental Limited | Administrative & support | 2009 |
| Driver CPC Yorkshire Limited | Professional & scientific | 2010 |
| Driver Stop Ltd | Information & communication | 2017 |
| Driver Street Holdings Limited | Financial services | 2022 |
| Driver Vehicle Maintenance Ltd | Wholesale & retail | 2023 |
| Driver VIK Ltd | Transport & logistics | 2023 |
| Drivetorque Motorsport Limited | Wholesale & retail | 2015 |
| Driveways (Leeds) Limited | Construction | 2001 |
| Driving Down Limited | Administrative & support | 2020 |
| DRK Project Limited | Construction | 2018 |
| DRM & AL Ltd | Transport & logistics | 2025 |
| DRM Facades Limited | Wholesale & retail | 1998 |
| DRM Ventures Limited | Financial services | 2024 |
| DRO Electrics Limited | Energy | 2023 |
| Drointon Logistics Ltd | Transport & logistics | 2014 |
| Dromonby Bridge Farm Limited | Agriculture & fishing | 2015 |
| Drop Dead Beauty Ltd | Other services | 2023 |
| Drop Nights Limited | Other services | 2018 |
| Dropdak Ltd | Information & communication | 2026 |
| Dropz Limited | Information & communication | 2025 |
| Drpers Limited | Health & social care | 2022 |
| Drridhibansal Limited | Professional & scientific | 2026 |
| DRS C&P Limited | Health & social care | 2014 |
| DRS Deals Ltd | Wholesale & retail | 2023 |
| DRS Education Group Limited | Financial services | 2025 |
| DRS Estates Limited | Real estate | 2023 |
| DRS J and H Cain Limited | Health & social care | 2019 |
| Drsa Construction & Engineering Limited | Construction | 2025 |
| Drshni Medical Services Limited | Health & social care | 2011 |
| DRT Metal Recycling Limited | Water & waste | 2009 |