| Ensure Care Ltd | Health & social care | 2012 |
| Enterprise Energy Limited | Manufacturing | 2022 |
| Entify Expand Limited | Professional & scientific | 2018 |
| Entrepreneursity Training Limited | Professional & scientific | 2023 |
| Entrust Care Partnership C.I.C. | Other services | 2013 |
| Enviro Games Limited | Information & communication | 2022 |
| Enviro Heating & Plumbing Ltd | Construction | 2023 |
| Enviro Resources Consultants Limited | Professional & scientific | 2016 |
| EPH (2017) Limited | Construction | 2017 |
| Epic Italy Limited | Administrative & support | 2024 |
| Epicc Limited | Education | 2021 |
| Equable Management Limited | Professional & scientific | 2020 |
| Equable Partners Limited | Information & communication | 2020 |
| Equibetter Ltd | Professional & scientific | 2022 |
| Equinox Licensing Limited | Information & communication | 2006 |
| Equity Evolution Ltd | Real estate | 2003 |
| Ergo Figure Limited | Information & communication | 2017 |
| Ergo Planet UK Holdings Ltd | Wholesale & retail | 2010 |
| Ergo Planet UK Limited | Wholesale & retail | 2011 |
| Ernest Hardy Construction Ltd | Construction | 2020 |
| Ernest Hardy Ltd | Real estate | 2017 |
| ERP Executive Solutions Ltd | Professional & scientific | 2014 |
| Errol Martin Ltd | Professional & scientific | 2003 |
| Eryxgear Ltd | Wholesale & retail | 2020 |
| Escada Eyecare Limited | Health & social care | 2011 |
| Escape Leamingtonspa Ltd | Arts & recreation | 2020 |
| Escapefinity Limited | Arts & recreation | 2024 |
| Esephus Limited | Wholesale & retail | 2020 |
| ESJ Global Limited | Wholesale & retail | 2023 |
| ESL Recruitment Ltd | Administrative & support | 2025 |
| Esla Consulting Ltd | Energy | 2021 |
| Esme Fletcher Photography Ltd | Arts & recreation | 2018 |
| Espana Catering Limited | Hospitality | 2019 |
| Espana Limited | Hospitality | 2016 |
| Espina Estates Ltd | Real estate | 2019 |
| Esprit Land Limited | Real estate | 2004 |
| Esque Limited | Other services | 2002 |
| Essencia Homes Limited | Construction | 2005 |
| Essential Events Limited | Other services | 1996 |
| Essential Fruit Limited | Wholesale & retail | 2012 |
| Essential Logistics Solutions Limited | Extraterritorial | 2014 |
| Estate Agent English Homes Limited | Real estate | 2012 |
| Ester Cosmetics Ltd | Wholesale & retail | 2024 |
| Etari Ltd | Wholesale & retail | 2023 |
| Eternal Art & Design Tattoo Studio Limited | Other services | 2015 |
| Ethels Place Ltd | Hospitality | 2026 |
| Ethica Healthcare Ltd | Health & social care | 2023 |
| Etta James Limited | Real estate | 2024 |
| Etzeo Limited | Wholesale & retail | 2019 |
| Euro Leamington Market Limited | Wholesale & retail | 2026 |
| Euro MIN Market Limited | Wholesale & retail | 2025 |
| Europa Real Estate Limited | Real estate | 2025 |
| European Resourcing Solutions Ltd | Extraterritorial | 2015 |
| Eurozone Property Developments Limited | Real estate | 2006 |
| Eustace Consulting Services Ltd | Professional & scientific | 2024 |
| Eustace Designs Ltd | Manufacturing | 2021 |
| EV Driveline Limited | Manufacturing | 2022 |
| EV Mcnamara Holdings Ltd | Construction | 2021 |
| EVA Action Consultancy Ltd | Professional & scientific | 2024 |
| Evans Admin Limited | Professional & scientific | 2017 |
| Evans Alignment Limited | Wholesale & retail | 2023 |
| Evans CC Ltd | Wholesale & retail | 2021 |
| Evans Kitchens & Bathrooms Limited | Construction | 2018 |
| Evans Paraplanning Limited | Administrative & support | 2016 |
| EVE Clinics Aesthetic & Medical Ltd | Health & social care | 2025 |
| EVE Clinics LLP | | 2020 |
| EVE Lidderth Social Work Training and Consultancy Ltd | Health & social care | 2017 |
| Evendine Care Limited | Health & social care | 2001 |
| Event Operation Specialists Limited | Administrative & support | 2022 |
| Event Support Team Ltd | Transport & logistics | 2014 |
| Eventfulmoments Ltd | Hospitality | 2024 |
| Events From History Limited | Arts & recreation | 2014 |
| Eventsbyhch Limited | Hospitality | 2025 |
| Ever Clean Services Ltd | Administrative & support | 2026 |
| Evera Consulting Limited | Administrative & support | 2021 |
| Everest Clinic Ltd | Professional & scientific | 2023 |
| Everest Fitness Centre Ltd | Education | 2021 |
| Everest Indian Takeaway UK Limited | Hospitality | 2019 |
| Everest Property Holdings Ltd | Financial services | 2018 |
| Everglow Electrical Limited | Construction | 2026 |
| Everly Supplies Ltd | Wholesale & retail | 2026 |
| Everwell Dental Practice Ltd | Health & social care | 2025 |
| Everwell Property Limited | Financial services | 2025 |
| Everyware Holdings Limited | Financial services | 2021 |
| Everyware Limited | Information & communication | 2015 |
| Evexia Group Ltd | Health & social care | 2025 |
| Evolution Capital Resources Ltd | Extraterritorial | 2003 |
| Evolve Construction Midlands Ltd | Construction | 2025 |
| Evolved Hair Limited | Other services | 2012 |
| Evorai Limited | Information & communication | 2025 |
| EVS Services Limited | Professional & scientific | 2019 |
| EX Pats Pantry Ltd | Wholesale & retail | 2020 |
| Ex-Situ Limited | Professional & scientific | 2008 |
| Excavo Limited | Professional & scientific | 2021 |
| Excellence Speaks Volumes Limited | Information & communication | 2021 |
| Excellent BIM Consulting Ltd | Professional & scientific | 2025 |
| Excellerated Engineering Limited | Professional & scientific | 2025 |
| Excellsys Ltd | Professional & scientific | 2024 |
| Executive Cars Rugby Limited | Transport & logistics | 2018 |
| Exercise Anywhere Limited | Arts & recreation | 2004 |