| Defined Design Limited | Professional & scientific | 2024 |
| Defty Luca Limited | Health & social care | 2019 |
| Delta Cassidy Special Opportunities 1 Ltd | Construction | 2025 |
| Delta Food Systems Limited | Administrative & support | 2005 |
| Delta Gamma Advisors Limited | Financial services | 2015 |
| Dempsey's Diamonds Limited | Administrative & support | 2017 |
| Denetal Limited | Professional & scientific | 2001 |
| Denfield Advertising & Marketing Limited | Professional & scientific | 2001 |
| Dengar Developments Limited | Real estate | 2016 |
| Dengar Holdings Ltd | Real estate | 2025 |
| Dengar Property Investments Limited | Real estate | 2025 |
| Denka Seiken UK Limited | Health & social care | 2002 |
| Denmylne Limited | Construction | 2006 |
| Dental Spa Solutions Ltd | Health & social care | 2014 |
| Dental Team Qualifications Limited | Education | 2012 |
| Dental Team Training Limited | Administrative & support | 2011 |
| Deploy AI: Decide-Control-Deploy Ltd | Professional & scientific | 2026 |
| Deploy Users Ltd | Professional & scientific | 2018 |
| Deredis UK Ltd | Extraterritorial | 2013 |
| Derma Medical Group Limited | Other services | 2024 |
| Dermatica Ltd | Wholesale & retail | 2017 |
| Desa Warwickshire Ltd | Hospitality | 2022 |
| Design Automation Systems Limited | Information & communication | 2001 |
| Design Buro (Coventry) Holding Limited | Financial services | 2019 |
| Design Buro (Coventry) Limited | Professional & scientific | 1997 |
| Design by Mills Limited | Professional & scientific | 2016 |
| Design Creative Properties Ltd | Real estate | 2023 |
| Design Speed Ltd | Professional & scientific | 2017 |
| Designaw Ltd | Professional & scientific | 2018 |
| Designbytouch Limited | Manufacturing | 2006 |
| Desti'Nei Records Ltd | Information & communication | 2020 |
| Deus Consortium Property Limited | Real estate | 2021 |
| DEV DAN Herd Limited | Information & communication | 2017 |
| Devall George Ltd | Manufacturing | 2023 |
| Development Engineering and Enterprise Ltd | Manufacturing | 2005 |
| Devotion Care Ltd | Health & social care | 2023 |
| DFD Global Ltd | Wholesale & retail | 2018 |
| DGH (Freehold) Limited | Real estate | 2006 |
| DGH Electrical Services Ltd | Construction | 2020 |
| DGS Logistic Services Ltd | Transport & logistics | 2016 |
| Dhami Haulage Limited | Transport & logistics | 2003 |
| Dhami Ventures Limited | Households | 2017 |
| Dhcs Aviation Ltd | Transport & logistics | 2024 |
| Dhcs Cyber Ltd | Information & communication | 2024 |
| Dhill Glazing Limited | Construction | 2019 |
| Dhillon & Sons Holding Ltd | Real estate | 2025 |
| Dhillon Sons Ltd | Wholesale & retail | 2026 |
| Dhoke 2 Ltd | Hospitality | 2014 |
| Dial Global Limited | Administrative & support | 2019 |
| Diamond Carpentry & Renovations Ltd | Construction | 2025 |
| Diamond Hair by Kate Limited | Other services | 2023 |
| Diane Metcalfe Consulting Limited | Professional & scientific | 2017 |
| Dibble Developments Limited | Construction | 1964 |
| Dibitronfast Limited | Information & communication | 1994 |
| Diffuse Retail Limited | Wholesale & retail | 2023 |
| Digby Antiques Limited | Wholesale & retail | 2013 |
| Digby Motors Limited | Professional & scientific | 2006 |
| Digisonic Ltd | Information & communication | 2023 |
| Digital MC Ltd | Professional & scientific | 2017 |
| Digital Work Research Ltd | Information & communication | 2015 |
| Digitalica Limited | Information & communication | 2022 |
| Dility Ltd | Information & communication | 2021 |
| Dilrai Boutique Ltd | Wholesale & retail | 2022 |
| Dingli Machinery UK Limited | Construction | 2018 |
| Dinkys Playcafe Limited | Hospitality | 2020 |
| Diperrimed Ltd | Health & social care | 2023 |
| DIR3CT Ltd | Administrative & support | 2008 |
| Direct Advantage Limited | Information & communication | 2013 |
| Direct Building Control Ltd | Extraterritorial | 2010 |
| Dirigo Engineering Limited | Professional & scientific | 2013 |
| Disact Ltd | Professional & scientific | 2020 |
| Discover Phenomenal Limited | Professional & scientific | 2020 |
| Disrupt Search Limited | Administrative & support | 2026 |
| Divs Design Engineering Limited | Professional & scientific | 2016 |
| Dixon Alderton Law Ltd | Professional & scientific | 2016 |
| Dixon BDS Limited | Administrative & support | 2016 |
| DJB IT Solutions Limited | Information & communication | 2013 |
| DJC Electrical Limited | Construction | 2024 |
| DJC Initiatives Limited | Hospitality | 2013 |
| DJG Property Limited | Real estate | 2016 |
| Djlovett Trading Ltd | Wholesale & retail | 2025 |
| DJP Diving Ltd | Wholesale & retail | 2026 |
| DJT Contractors Limited | Professional & scientific | 2022 |
| DKG Communications Ltd | Information & communication | 2013 |
| DLH Creative Studio Ltd | Professional & scientific | 2022 |
| DLN Management Ltd | Professional & scientific | 2019 |
| DLN Property Investments Ltd | Real estate | 2025 |
| DM Prop Ltd | Real estate | 2021 |
| Dmak Capital Limited | Professional & scientific | 2025 |
| Dmcf Ltd | Real estate | 2025 |
| DMG Management Consultancy Limited | Professional & scientific | 2026 |
| DMR Building & Maintenance Ltd | Construction | 2025 |
| Dnatabasics Ltd | Extraterritorial | 2009 |
| DNB ID Ltd | Information & communication | 2026 |
| DNR Recruitment Group Ltd | Administrative & support | 2025 |
| Document Advisor Ltd | Professional & scientific | 2025 |
| Does QA Ltd | Information & communication | 2022 |
| Doglane Fishery Limited | Agriculture & fishing | 2016 |
| Dolphin Swimming Academy Limited | Education | 2016 |
| Dolton Calculations Limited | Professional & scientific | 2023 |