| Smiley Happy People (Trethorne) Ltd | Health & social care | 2022 |
| Smiley Happy People Ltd | Health & social care | 2022 |
| Solarscape Ltd | Professional & scientific | 2024 |
| Solgen Commercial Ltd | Construction | 2002 |
| Solgen Holdings Ltd | Financial services | 2021 |
| South Farthing Limited | Wholesale & retail | 2026 |
| South West Care Solutions Ltd | Administrative & support | 2005 |
| South West Natural Solutions Ltd. | Professional & scientific | 2025 |
| South West Truck and Trailer Parts Limited | Wholesale & retail | 2013 |
| South West Utilities Solutions Ltd | Information & communication | 2022 |
| South Wheatley Environmental Trust | Energy | 2004 |
| Southern Court 2000 Car Sales Ltd | Wholesale & retail | 2023 |
| Southwest Accounts and Management Services Ltd | Professional & scientific | 2017 |
| Southwestvansales Ltd | Wholesale & retail | 2025 |
| SP Deckings Ltd | Construction | 2022 |
| Sparrow Stoves Ltd | Construction | 2023 |
| SPC Building Ltd | Construction | 2019 |
| Special Vehicle Services Limited | Wholesale & retail | 1986 |
| Sphere Systems Limited | Information & communication | 1997 |
| Spice Settlement Trust Limited(The) | Transport & logistics | 1951 |
| Split Climbing Ltd | Wholesale & retail | 2024 |
| Sport Craft Ltd | Education | 2023 |
| Sports Metals Ltd | Manufacturing | 2007 |
| Spraytech Limited | Agriculture & fishing | 1996 |
| Spreadburyinc Ltd | Wholesale & retail | 2020 |
| Spry's of Launceston Limited | Wholesale & retail | 1977 |
| Spume FM Limited | Information & communication | 2024 |
| SRD Shillaber Race Design Limited | Wholesale & retail | 2002 |
| ST Johns (Launceston) Limited | Households | 2016 |
| ST Nicholas Church (Tresmeer) Limited | Arts & recreation | 2022 |
| ST Tinney Ltd | Hospitality | 2018 |
| Stambridge Consultants Ltd | Wholesale & retail | 2025 |
| Stambridge Properties Ltd. | Financial services | 2023 |
| Steam Pipe Company Ltd | Hospitality | 2018 |
| Stella Rooflight Limited | Manufacturing | 2023 |
| Stenlakes Holdings Limited | Professional & scientific | 2004 |
| Stenmor Resources Ltd | Mining & quarrying | 2025 |
| Steppenwolf Ltd | Health & social care | 2019 |
| Stevenson Homes Limited | Construction | 2001 |
| Stourscombe JWP Ltd | Administrative & support | 2025 |
| Studio Zest Limited | Health & social care | 2014 |
| Summit Group (SW) Limited | Financial services | 2025 |
| Summit Group Civils Ltd | Construction | 2025 |
| Sun WAH 18 Limited | Hospitality | 2023 |
| Sun WAH 275 Limited | Hospitality | 2026 |
| Sunchaser Inns Ltd | Hospitality | 2016 |
| Sunny Launceston Ltd | Hospitality | 2025 |
| Sureline Blasting Limited | Professional & scientific | 2007 |
| Sureline Finishing Limited | Manufacturing | 2001 |
| Susceptum Consulting Limited | Professional & scientific | 2025 |
| Sustain Media Group Limited | Information & communication | 2017 |
| SW Valeting Car Wash Ltd | Administrative & support | 2025 |
| SWB Farms Limited | Agriculture & fishing | 2007 |
| Swell Breaks Ltd | Information & communication | 2026 |
| Swift 565 Limited | Wholesale & retail | 2002 |
| Swws Cornwall Ltd | Agriculture & fishing | 2015 |
| T J Pearce Groundworks Limited | Construction | 2023 |
| Tamar Automation Limited | Professional & scientific | 2018 |
| Tamar International Property Investment Ltd | Real estate | 2024 |
| Tamar Koffi Ltd | Wholesale & retail | 2012 |
| Tamar Self Storage Limited | Extraterritorial | 2020 |
| Tamar Softwash Ltd. | Administrative & support | 2025 |
| Tamar Valley Meats Limited | Wholesale & retail | 2006 |
| Tamar Vista Management Company Limited | Real estate | 2010 |
| Tckh Ltd | Professional & scientific | 2019 |
| Techfront SW Ltd | Administrative & support | 2025 |
| Tempus Fugit Ventures Limited | Education | 2002 |
| Terry Collins Design and Engineering Limited | Professional & scientific | 2007 |
| Terry Graves Electrical Limited | Construction | 2006 |
| TGB Consulting Services Limited | Professional & scientific | 2025 |
| THC CBD Company Limited | Wholesale & retail | 2020 |
| THE Art of Light Limited | Wholesale & retail | 1999 |
| THE Backstage BUS Limited | Administrative & support | 2018 |
| THE Bell Inn Limited | Hospitality | 2026 |
| THE Big FAT Burrito Co Ltd | Administrative & support | 2019 |
| THE Brate Group Ltd | Wholesale & retail | 2015 |
| THE BUG N PIN Ltd | Arts & recreation | 2025 |
| THE Cadogan Trading Company Limited | Professional & scientific | 1994 |
| THE Charles Causley Trust | Wholesale & retail | 2012 |
| THE Cornwall Garden Society | Education | 2002 |
| THE Enriching Group Limited | Construction | 2022 |
| THE Flawless Firm Ltd | Wholesale & retail | 2025 |
| THE Gentleman Magazine Limited | Information & communication | 2016 |
| THE Jetwash Co by G.A.W. Washes Ltd | Administrative & support | 2024 |
| THE John Holmes Partnership Ltd | Professional & scientific | 2019 |
| THE Knotted Napkin Co Ltd | Hospitality | 2023 |
| THE Lark Ascending Limited | Transport & logistics | 2001 |
| THE Launceston Rural Learning Trust | Education | 2012 |
| THE Launceston Timber Co Ltd | Manufacturing | 2022 |
| THE Little Bike Shop Ltd | Wholesale & retail | 2014 |
| THE Natural Fibre Company Holdings Limited | Manufacturing | 2019 |
| THE Natural Fibre Company Limited | Manufacturing | 2005 |
| THE Old Mill & Barn Ltd | Hospitality | 2020 |
| THE Outside Inn Cuisine Ltd | Hospitality | 2021 |
| THE Phone Ranger Ltd | Wholesale & retail | 2018 |
| THE Short Distilling Company Ltd | Manufacturing | 2020 |
| THE Sydenham Shooting Club Limited | Agriculture & fishing | 2012 |
| THE Technology Transformation Consultancy Ltd | Information & communication | 2019 |
| THE Walk in Shower Specialists Ltd | Extraterritorial | 2026 |
| Thesendmate Ltd | Information & communication | 2026 |