| Cornish Timber Products Ltd | Manufacturing | 2023 |
| Cornwall & Devon Logistics Limited | Transport & logistics | 2018 |
| Cornwall & Devon Motocross Club Ltd | Arts & recreation | 2017 |
| Cornwall Carpets and Flooring Ltd | Construction | 2014 |
| Cornwall Renewable Developments Limited | Energy | 2011 |
| Cornwall Resilience Group Limited | Construction | 2024 |
| Cornwall Wash Centres Ltd | Administrative & support | 2023 |
| Country Chic Limited | Wholesale & retail | 2022 |
| CP Holdings SW Ltd | Transport & logistics | 2024 |
| CP Nitro Ltd | Administrative & support | 2003 |
| CPT Automation Ltd | Professional & scientific | 2024 |
| Craig Frain Plant Hire Ltd | Administrative & support | 2021 |
| Crawley & Masters Limited | | 1962 |
| Creative Storage Limited | Construction | 2003 |
| Crowndale Estates (Tavistock) Ltd | Real estate | 2018 |
| CS Carpentry and Roofing Ltd | Manufacturing | 2026 |
| D & C Properties (Cornwall) Limited | Real estate | 2024 |
| D K Sweets Ltd | Wholesale & retail | 2024 |
| D&T Dairy Engineering Limited | Professional & scientific | 2024 |
| D.W. Smith Tractor Sales Limited | Wholesale & retail | 1997 |
| Dairywell Estates Limited | Real estate | 2000 |
| Danny Smith Farrier Ltd | Agriculture & fishing | 2023 |
| Darkes Court Management Company Limited | Households | 2006 |
| Darkwood Consulting Limited | Information & communication | 2009 |
| Dart Wealth Management Limited | Administrative & support | 2017 |
| Dartmoor Shoot Catering Limited | Hospitality | 2018 |
| Dave KBS Limited | Wholesale & retail | 2012 |
| Davey's Livestock Transport Limited | Financial services | 1993 |
| David J Robinson Estate Agents and Auctioneers Ltd | Real estate | 2020 |
| David Rogers Plumbing & Heating Limited | Construction | 2014 |
| Davidstow & Westmoor Commons Limited | Agriculture & fishing | 2002 |
| Davidstow Creamery Direct Ltd | Agriculture & fishing | 2004 |
| DBD Contracts Limited | Transport & logistics | 2003 |
| DED Creative Ltd | Professional & scientific | 2024 |
| Deedplot Limited | Households | 1992 |
| Deep Thought Creative Ltd. | Professional & scientific | 2016 |
| Define Kitchens, Bathrooms and Bedrooms Ltd | Wholesale & retail | 2014 |
| Define Okehampton Ltd | Wholesale & retail | 2025 |
| Define Property Ltd | Real estate | 2020 |
| Degg CAD Services Ltd. | Information & communication | 2001 |
| Dejay Distribution Limited | Wholesale & retail | 1991 |
| Desmond and Company Limited | Extraterritorial | 2013 |
| Devon and Cornwall Logs Limited | Agriculture & fishing | 2014 |
| Devon Classic Buses Limited | Transport & logistics | 2025 |
| Dewcombe Ltd | Agriculture & fishing | 2026 |
| Diamond Road 1959 Limited | Extraterritorial | 2014 |
| Dillon Prime Limited | Information & communication | 2003 |
| DMS Technical Consultancy Ltd | Information & communication | 2024 |
| DOT Plays Piano Ltd | Education | 2025 |
| Dove Property Solutions SW Ltd | Real estate | 2025 |
| Dove SPV 1 Ltd | Real estate | 2026 |
| Downton DRY Cleaners Ltd | Other services | 2012 |
| Drained: Batteries NOT Included Ltd | Wholesale & retail | 2025 |
| Duchy Autos Limited | Wholesale & retail | 2017 |
| Duchy View Management Company Limited | Professional & scientific | 2007 |
| Duncan Williams Limited | Information & communication | 1983 |
| DW Construction (South West) Ltd | Construction | 2018 |
| Dwce Ltd | Agriculture & fishing | 2017 |
| DWM (Cornwall) Limited | Financial services | 2018 |
| Dynamic Descaler UK Limited | Wholesale & retail | 2007 |
| E & J Projects Ltd | Construction | 2016 |
| E Hayden Associates Ltd | Professional & scientific | 2021 |
| East Cornwall Lets Ltd | Real estate | 2020 |
| Eastmoor Common Limited | Agriculture & fishing | 2005 |
| Easytrail Limited | Real estate | 1988 |
| Ebuild UK Ltd | Wholesale & retail | 2009 |
| Eco Elevations Limited | Construction | 2019 |
| Eco Solutions Global Limited | Wholesale & retail | 2021 |
| Ecology Training UK Ltd | Professional & scientific | 2019 |
| Eden Trailers Ltd | Manufacturing | 2026 |
| Edymead Court Management Company Limited | Households | 2004 |
| Eivrah Limited | Other services | 2021 |
| EJ FRY Transport and Plant Hire Limited | Transport & logistics | 2012 |
| Ej's Motors Ltd | Wholesale & retail | 2024 |
| Ekho Logistics (UK) Ltd | Transport & logistics | 2024 |
| Electrascale Limited | Professional & scientific | 2026 |
| Ellacott Motors and MOT Centre Ltd | Wholesale & retail | 2021 |
| Elmsgrove Community Arts CIC | Information & communication | 2025 |
| Elmslea 1995 Limited | Health & social care | 2004 |
| Elvidge Gribble Ltd | Administrative & support | 2003 |
| Elworth Management Company Limited | Households | 2005 |
| Elys Homes Limited | Households | 2022 |
| Email Hippo Limited | Information & communication | 2015 |
| Endeavour Shellfish Ltd | Agriculture & fishing | 2022 |
| Energy Assessment South West Ltd | Other services | 2020 |
| Engineering Technical Support Ltd | Professional & scientific | 2024 |
| English Guernsey Cattle Society(The) | Agriculture & fishing | 1927 |
| Enigma Audio Group Limited | Manufacturing | 2018 |
| Ennandkay Ltd | Real estate | 2024 |
| Equicare Ltd | Agriculture & fishing | 2023 |
| Erudition Consultancy Ltd | Education | 2024 |
| ESG Boilercare Limited | Administrative & support | 2006 |
| Eurocoupling Limited | Professional & scientific | 1989 |
| Evans Developments Limited | Construction | 2006 |
| Everify Limited | Information & communication | 2011 |
| Exciting Education Ltd | Education | 2015 |
| Exeter Disability Centre Limited | Administrative & support | 2002 |
| Express Hand Car Wash Launceston Ltd | Administrative & support | 2023 |
| Faces by Laura Limited | Health & social care | 2026 |
| Fair Oak Properties Exeter Limited | Real estate | 2015 |