| Crystal Mcclory Limited | Arts & recreation | 2002 |
| Csee Holdings Limited | Real estate | 2024 |
| CSR Communications Ltd | Wholesale & retail | 2024 |
| CUBE3NERGY Ltd | Professional & scientific | 2023 |
| Cult Athletics Ltd | Wholesale & retail | 2025 |
| Curry and Harry Ltd | Hospitality | 2022 |
| Custom Climates Limited | Energy | 2011 |
| CW Competitions Ltd | Wholesale & retail | 2024 |
| Cyber Medici Limited | Information & communication | 2021 |
| CYBER123 Ltd | Administrative & support | 2017 |
| Cypress Court Management Limited | Administrative & support | 1973 |
| D & G Brown Commercials Limited | Transport & logistics | 2014 |
| D & M Enterprises (UK) Limited | Wholesale & retail | 2012 |
| D Follows Roofing Limited | Construction | 2012 |
| D H Drywall Ltd | Construction | 2012 |
| D&D Electrical Contractors Limited | Construction | 2012 |
| D'Chimes Consulting Ltd | Professional & scientific | 2024 |
| D.J.K.Leadwork & Roofing Specialists Ltd | Construction | 2020 |
| Daffodil Cleaning Services Ltd | Administrative & support | 2016 |
| Dairy Lane TML Ltd | Construction | 2025 |
| DAL Tiling Ltd | Construction | 2024 |
| Daniel Associates 1989 Ltd | Financial services | 2020 |
| David Michael Williams Limited | Real estate | 2012 |
| Davies and Harrison Limited | Real estate | 2023 |
| Dawson Heating Ltd | Construction | 2009 |
| Day Group Process Servers Limited | Administrative & support | 2015 |
| Days Waste Warriors Ltd | Water & waste | 2024 |
| DB Automotive Group Ltd | Wholesale & retail | 2017 |
| DB Strategy Group Limited | Professional & scientific | 2023 |
| DBK Aero Ltd | Transport & logistics | 2019 |
| DC Procurement Services Ltd | Professional & scientific | 2026 |
| Dean Ager Limited | Arts & recreation | 2016 |
| Dean Widdows Limited | Construction | 2003 |
| Deans Roofing & Building Limited | Construction | 2024 |
| Debatin UK Ltd | Wholesale & retail | 2009 |
| Define Engineers Ltd | Professional & scientific | 2017 |
| Defuse Training Limited | Education | 2008 |
| Delos Project Ltd | Real estate | 2022 |
| Deluxe Care Ltd | Health & social care | 2014 |
| Demon Designs Limited | Manufacturing | 2016 |
| Dennis & Robinson Limited | Manufacturing | 1948 |
| Designerbuilder Ltd | Hospitality | 2016 |
| Destination Bike Limited | Wholesale & retail | 2015 |
| Dexter Corporation Limited | Construction | 2003 |
| DF Audio Ltd | Professional & scientific | 2007 |
| DG Investment Management Limited | Extraterritorial | 2018 |
| DGQ Services Limited | Professional & scientific | 2008 |
| Diamond Waters Widewater RTM Company Limited | Other services | 2008 |
| Dice Saloon Limited | Wholesale & retail | 2015 |
| Dickie Ltd | Professional & scientific | 2018 |
| Diktyon Ltd | Financial services | 2024 |
| Diving Support UK Ltd | Professional & scientific | 2014 |
| Dixon Building Services Limited | Construction | 2014 |
| DJ MR Chips Ltd | Arts & recreation | 2025 |
| DJ8CH Limited | Construction | 2024 |
| DJM Windblade Limited | Professional & scientific | 2023 |
| DMH Electrical Installations Limited | Construction | 2021 |
| DNM Camping Ltd | Extraterritorial | 2024 |
| DNM Outdoor Ltd | Wholesale & retail | 2024 |
| DNM Retail Ltd | Extraterritorial | 2024 |
| DNS Holdings Limited | Real estate | 2025 |
| Done Roaming CIC | Real estate | 2025 |
| Doro Properties Ltd | Real estate | 2021 |
| Dotconnected Limited | Information & communication | 2004 |
| DPR Online Trading Ltd | Wholesale & retail | 2020 |
| Dregvas Property Limited | Real estate | 2021 |
| Drewnell Properties Limited | Construction | 1994 |
| Drip & Puff Ltd | Wholesale & retail | 2026 |
| DUO Worthing Limited | Hospitality | 2023 |
| Dure Adeel Ltd | Wholesale & retail | 2026 |
| Duxbury Advisory Limited | Other services | 2012 |
| DV Business Solutions Limited | Administrative & support | 2015 |
| Dynamic Art Nest Co Ltd | Administrative & support | 2019 |
| Dynamic Drawings Limited | Information & communication | 1996 |
| Dyson Gymnastics Ltd | Education | 2018 |
| E & S Financial Planning Ltd | Other services | 2019 |
| Earling Property Limited | Real estate | 2019 |
| East 70 Consultancy Ltd | Professional & scientific | 2025 |
| East Lodge (Lancing) Residents Company Limited | Households | 1989 |
| Eastern European Security Investments Limited Partnership | | 2017 |
| Eastmont Holdings Limited | Real estate | 2016 |
| Eco-Eye Limited | Manufacturing | 2012 |
| ED2 Digital Limited | Information & communication | 2020 |
| Edge Developments Ltd | Construction | 2020 |
| Edgeway Building Services Limited | Construction | 2012 |
| Edgeway Property Development Limited | Real estate | 2020 |
| Edifice Construction Consultancy Limited | Professional & scientific | 2022 |
| Editmike Limited | Information & communication | 2017 |
| Eesi General Partner LLP | | 2017 |
| Effective Governance Forum Ltd | Education | 2019 |
| Effective Shield Solutions Ltd | Construction | 2024 |
| EGB Precision Ltd | Manufacturing | 2019 |
| Elec Test Sussex Limited | Construction | 2020 |
| Electric Storm Youth Limited | Arts & recreation | 2007 |
| Electrocore UK, Ltd. | Wholesale & retail | 2015 |
| Elements Electrical Limited | Construction | 2024 |
| Elite Decorators Ltd | Construction | 2009 |
| Elite Heat Sussex Ltd | Construction | 2026 |
| Elite Line Telecom Limited | Information & communication | 2026 |
| Eltonstone Limited | Real estate | 1984 |