| Wrenman Homes Ltd | Professional & scientific | 2017 |
| Wrenman Lancaster Ltd | Construction | 2017 |
| Wrenman Strategic Land Limited | Construction | 2022 |
| Wrenn Industry Limited | Financial services | 2023 |
| Wright Risk Limited | Financial services | 2021 |
| WT Business Consulting Ltd | Professional & scientific | 2017 |
| WT Infotech Private Limited | Information & communication | 2012 |
| WVC Lancaster Ltd | Construction | 2020 |
| WW Capital Management Ltd | Information & communication | 2020 |
| Wyre Drives & Patios Limited | Administrative & support | 2020 |
| Wyresdale Holdings Ltd | Financial services | 2023 |
| Wyreside Mushrooms Ltd | Agriculture & fishing | 2022 |
| X Force Group Limited | Arts & recreation | 2012 |
| X-Force UK Ltd | Wholesale & retail | 2011 |
| Xeroxpro Consulting Ltd | Information & communication | 2020 |
| Xiborg Solutions Ltd | Construction | 2026 |
| XMP Consulting Limited | Professional & scientific | 2026 |
| Yaaa Foods Ltd | Hospitality | 2021 |
| Yates Property Enterprise Limited | Real estate | 2024 |
| Yates Rail Ltd. | Construction | 2019 |
| Ydmt Consultants Limited | Professional & scientific | 1997 |
| YEM Theatre School Limited | Arts & recreation | 2025 |
| YES Flinked Limited | Professional & scientific | 2022 |
| YES Move Ltd | Real estate | 2020 |
| Yordas Digital Limited | Information & communication | 2006 |
| Yordas Group Limited | Financial services | 2017 |
| Yordas Limited | Professional & scientific | 2007 |
| Yorkshire Energy GAS Ltd | Construction | 2019 |
| YOU HQ Ltd | Other services | 2023 |
| Your Design Partner Ltd | Manufacturing | 2014 |
| Yourdentist (Lancaster) Limited | Health & social care | 2007 |
| YY Catering Limited | Hospitality | 2019 |
| YY Consulting Ltd | Information & communication | 2021 |
| YY Investing Ltd | Real estate | 2023 |
| Z Dance (Evesham) Limited | Arts & recreation | 2024 |
| Z Investment Holdings LLP | | 2015 |
| Z-Capital Ltd | Financial services | 2015 |
| Zain Phones Limited | Wholesale & retail | 2025 |
| ZD Franchise Limited | Arts & recreation | 2024 |
| Zeetta Limited | Hospitality | 2026 |
| Zelma Properties Ltd | Real estate | 2025 |
| ZEN Minded Limited | Wholesale & retail | 2013 |
| Zenith Built Heritage LLP | | 2026 |
| Zentek Digital Investigations Ltd | Information & communication | 2021 |
| Zero Cars Ltd | Transport & logistics | 2019 |
| Zest Dance Ltd | Arts & recreation | 2020 |
| Zest Publications Limited | Information & communication | 2013 |
| ZHD Ltd | Education | 2026 |
| Zosh Occupational Health Academy Ltd | Public administration | 2023 |
| Zosh Occupational Health Limited | Health & social care | 2019 |