| Dunning Development Ltd | Information & communication | 2024 |
| E C Habitats Limited | Professional & scientific | 2026 |
| E C Heritage Ltd | Construction | 2015 |
| E-Arth Property Services Ltd | Real estate | 2025 |
| E-Vate EOT Limited | Financial services | 2026 |
| E-Vate Ltd | Professional & scientific | 2010 |
| E.C.L. Hardman Ltd | Real estate | 2016 |
| E.D.M.S. (U.K.) Limited | Administrative & support | 2014 |
| Earthware Limited | Information & communication | 2007 |
| Easier Said Than Run Club Ltd | Wholesale & retail | 2024 |
| Eastwalk Properties Ltd | Real estate | 2011 |
| Easylink Freight Limited | Transport & logistics | 2021 |
| EB NOW Limited | Administrative & support | 2024 |
| EBA Group Limited | Professional & scientific | 2008 |
| Eccles Partners Limited | Real estate | 2019 |
| Eccleston City Estates Limited | Real estate | 2014 |
| Eco-Homeuk Ltd | Construction | 2020 |
| Ecsus Design Limited | Professional & scientific | 2014 |
| Eddie Alexander Limited | Professional & scientific | 2022 |
| Eden Luxury Travel Limited | Administrative & support | 2016 |
| Edgar Naylor Ltd | Wholesale & retail | 2024 |
| Edge Product Development Limited | Professional & scientific | 2001 |
| Edict Limited | Information & communication | 2014 |
| Edmundson Distribution Limited | Extraterritorial | 1960 |
| Edmundson Electrical Limited | Wholesale & retail | 1991 |
| Edmundson Electrical Pension Trustees Limited | Other services | 1979 |
| Edmundson Export Limited | Extraterritorial | 2006 |
| Edward Investments Group Limited | Real estate | 2025 |
| Edward Williams Consulting Ltd | Professional & scientific | 2019 |
| EE Haulage Holdings Limited | Financial services | 2024 |
| EFM Fleet Services Limited | Wholesale & retail | 2015 |
| Egde Ltd | Information & communication | 2024 |
| Egerton Property Services Ltd | Households | 2020 |
| Egertons Fleet Management Limited | Wholesale & retail | 2015 |
| Egertons Highways Services Limited | Wholesale & retail | 2018 |
| Egertons Holdings Limited | Financial services | 2016 |
| Egertons Recovery Limited | Extraterritorial | 2012 |
| EGN Digital Ltd | Information & communication | 2014 |
| EJC Services Ltd | Information & communication | 2025 |
| Electric Center Limited | Extraterritorial | 1976 |
| Electricenter Limited | Extraterritorial | 1980 |
| ELEV8 Consulting (Cheshire) Ltd | Professional & scientific | 2026 |
| Elite Dream Bedding Limited | Extraterritorial | 2014 |
| Elite Fitness and Health Limited | Health & social care | 2012 |
| Elixir Consultancy Limited | Professional & scientific | 2026 |
| Elliff Limited | Information & communication | 2011 |
| Ellis Mitchell Properties Limited | Extraterritorial | 1987 |
| Elmridge Investments Ltd | Real estate | 2019 |
| Elmside Care Limited | Professional & scientific | 2008 |
| Eloise Design Solutions Limited | Professional & scientific | 2025 |
| Elsar Group Ltd | Professional & scientific | 2023 |
| Elwilhar Limited | Real estate | 2025 |
| Ember INK Publishing Limited | Information & communication | 2025 |
| EMC Capital Ltd | Financial services | 2020 |
| EMC Estates Ltd | Real estate | 2024 |
| EMC Fleet Installations Limited | Professional & scientific | 2010 |
| EMC Property Holdings Ltd | Real estate | 2015 |
| EMC Surface Technologies Limited | Manufacturing | 2011 |
| Emerse Health Ltd | Professional & scientific | 2011 |
| Emma Beaumont Bespoke Ltd | Other services | 2017 |
| Emma Beaumont Design Ltd | Other services | 2017 |
| Emma Williams Studio Ltd | Arts & recreation | 2023 |
| Empathy Healthcare Limited | Health & social care | 2014 |
| Empower Dance Ltd | Education | 2026 |
| Enca Properties Ltd | Construction | 2015 |
| Encompass Connections Limited | Energy | 2022 |
| Encompass Electricity Limited | Energy | 2021 |
| Encompass Environmental & Renewables Limited | Professional & scientific | 2022 |
| Encompass GAS Limited | Energy | 2021 |
| Encompass Metering and Data Limited | Hospitality | 2022 |
| Encompass Utilities Limited | Financial services | 2021 |
| Encompass Water Limited | Water & waste | 2021 |
| Enerbee Energy Solutions Limited | Professional & scientific | 2025 |
| Energy Portfolio (UK) Ltd | Energy | 2023 |
| Energy Portfolio Ltd | Energy | 2012 |
| Engage AO Ltd | Health & social care | 2022 |
| Engineering Services Partnership Limited | Professional & scientific | 1997 |
| Engineering Talks Limited | Education | 2023 |
| Engraive Ltd | Information & communication | 2025 |
| Enigma Console Solutions Ltd | Wholesale & retail | 2024 |
| Ennis Commercial Vehicle Sales Limited | Wholesale & retail | 2017 |
| Ensenar Limited | Education | 2019 |
| Entilely Commercial Tiling Limited | Construction | 2005 |
| Environclean UK Ltd | Administrative & support | 2020 |
| EOS Tradelink Limited | Wholesale & retail | 2010 |
| Equiport Limited | Manufacturing | 1994 |
| Equityway Andover Ltd | Construction | 2025 |
| Equityway Bradford Ltd | Construction | 2024 |
| Equityway Care Ltd | Financial services | 2025 |
| Equityway Holdings Ltd | Financial services | 2022 |
| Equityway Kidsgrove Ltd | Construction | 2024 |
| Equityway Tunstall Ltd | Construction | 2024 |
| Equus Polymer Limited | Manufacturing | 1975 |
| Eran House Management Company Limited | Real estate | 2007 |
| Eric Edwards Haulage Contractor Limited | Transport & logistics | 1981 |
| ERP Rsrch Ltd | Professional & scientific | 2026 |
| Esmee Studio London Limited | Arts & recreation | 2012 |
| Euro Screens Limited | Information & communication | 2002 |
| Eurogenerators (UK) Limited | Administrative & support | 2006 |
| Eurostart UK Ltd | Professional & scientific | 2012 |