| CWH Carpentry Ltd | Construction | 2024 |
| CX North Yorkshire Ltd | Professional & scientific | 2024 |
| Cyber Primed Limited | Information & communication | 2016 |
| D & S Angling Supplies Limited | Wholesale & retail | 2003 |
| D J Fuller Railway Safety Assessment Limited | Transport & logistics | 2015 |
| D L Garage Equipment Limited | Manufacturing | 2024 |
| DA Projects Limited | Construction | 2016 |
| Daily Care (Services) Ltd | Health & social care | 2012 |
| Dales Radio Limited | Information & communication | 2013 |
| Dalesford Ltd | Information & communication | 2021 |
| Daleside Brewery Limited | Manufacturing | 1998 |
| Dandelion Arts Limited | Arts & recreation | 2020 |
| Darley Meadows Limited | Construction | 2021 |
| Darnbrough & Co Ltd | Professional & scientific | 2008 |
| Dash Capital Ltd | Real estate | 2021 |
| Datatrans Communications Limited | Information & communication | 1998 |
| David Audsley Hairdressing Limited | Other services | 2011 |
| David IAN Limited | Wholesale & retail | 1988 |
| David Watson Building (Yorkshire) Limited | Construction | 2019 |
| DB Pharm Limited | Professional & scientific | 2023 |
| DCG Technologies Ltd | Information & communication | 2025 |
| Decksaver Design Holdings LLP | | 2016 |
| Deewat Limited | Real estate | 2024 |
| Delamont Ltd | Information & communication | 2005 |
| Delta-Im Ltd | Professional & scientific | 2014 |
| Denis Procter Associates Limited | Professional & scientific | 2001 |
| Dennis Heating Limited | Construction | 2025 |
| Designs by Jade Ltd | Arts & recreation | 2024 |
| DHM Developments & Consultancy Limited | Real estate | 2006 |
| Didomi Ltd | Extraterritorial | 2024 |
| Digitley Limited | Information & communication | 2018 |
| Dilraj Ltd | Hospitality | 2023 |
| Dilraj Takeaway Ltd | Hospitality | 2026 |
| Dimeg Investments Ltd | Hospitality | 2019 |
| Dimond Ventilation Limited | Wholesale & retail | 2019 |
| Direct UNI Bills Ltd | Other services | 2025 |
| Disco Dayze Limited | Arts & recreation | 2024 |
| Diveshack UK Ltd | Education | 2018 |
| DJB81 Limited | Professional & scientific | 2025 |
| DJN Accountants & Tax Advisors Ltd | Professional & scientific | 2023 |
| DJN Accountants Limited | Professional & scientific | 2009 |
| Dlmt Ltd | Education | 2016 |
| DLT Developments Limited | Construction | 2007 |
| DMM Training and Development Limited | Administrative & support | 2015 |
| Dominus Developments Limited | Real estate | 2003 |
| Donkey's Years Antiques Ltd | Wholesale & retail | 2017 |
| Douvan Ltd | Professional & scientific | 2016 |
| Dovecote Mews Management Company Limited | Households | 2025 |
| DPO4U Ltd | Professional & scientific | 2022 |
| DR Claire Ltd | Health & social care | 2018 |
| Drapers House SPV Limited | Real estate | 2024 |
| Driff Cothing Limited | Wholesale & retail | 2025 |
| Driskell Ltd | Information & communication | 2025 |
| DTC Plastering Ltd | Construction | 2021 |
| Dual Communications Limited | Administrative & support | 2011 |
| DUO Conference and Events Ltd | Administrative & support | 2011 |
| Dynoclean Limited | Administrative & support | 2017 |
| Dynoclean Restoration Ltd | Other services | 2025 |
| E & M Rivera Limited | Wholesale & retail | 2012 |
| E Beachill Ltd | Administrative & support | 2025 |
| E. a. T. Electrical Solutions Limited | Manufacturing | 2018 |
| Eagle and Crown Enterprises Limited | Real estate | 2023 |
| Earlswood Construction Ltd | Construction | 2019 |
| Eastwood Services (UK) Ltd | Agriculture & fishing | 2016 |
| Ecoperspective Ltd | Professional & scientific | 2009 |
| Ed-Diy Limited | Other services | 2020 |
| Eden Gardens Builders and Developers Ltd | Real estate | 2026 |
| Educational Insight Ltd | Professional & scientific | 2023 |
| EGM Group Ltd | Wholesale & retail | 2024 |
| EGM Landscapes Ltd | Administrative & support | 2016 |
| EGW Investments Limited | Financial services | 2025 |
| Eiger Estates Limited | Real estate | 2021 |
| Eight Park Parade Limited | Households | 2021 |
| EK Events Ltd | Administrative & support | 2018 |
| Elara Intelligence Ltd | Information & communication | 2025 |
| Eleanoraesthetics Ltd | Health & social care | 2024 |
| Electric Powertrain Limited | Extraterritorial | 2022 |
| Elite Scaffolding Yorkshire Limited | Administrative & support | 2012 |
| ELJ Construction Services Ltd | Professional & scientific | 2022 |
| ELM Aesthetics Limited | Health & social care | 2022 |
| Elora Glow Ltd | Real estate | 2026 |
| Elsworth Tuition Ltd | Education | 2022 |
| Eltranet Design Limited | Construction | 2015 |
| Elyst Limited | Wholesale & retail | 2022 |
| Empirio Consulting Limited | Professional & scientific | 2019 |
| Engineu Limited | Professional & scientific | 2015 |
| Engravia Digital Limited | Wholesale & retail | 2015 |
| Enyo Talent Ltd | Administrative & support | 2025 |
| Eskdale View Management Company Limited | Households | 2023 |
| Espressa Grill and Kebab Limited | Hospitality | 2023 |
| Espressa Pizza Limited | Hospitality | 2023 |
| Espressa Takeaway & Delivery Ltd | Hospitality | 2026 |
| Eternal Beauty Spa Ltd | Other services | 2005 |
| Eternegy Limited | Information & communication | 2015 |
| Euroczechit Training Ltd | Information & communication | 2010 |
| Even US Ltd | Information & communication | 2025 |
| Evidar Ltd | Real estate | 2021 |
| EVO Bespoke Solutions LLP | | 2011 |
| Evolution Tree Care (Yorkshire) Ltd | Agriculture & fishing | 2025 |
| EW Taylor Limited | Construction | 2015 |