| S Chapman Holdings Limited | Real estate | 2023 |
| S-Cape Travel UK Limited | Administrative & support | 2021 |
| Sandbanks Capital Partners Limited | Professional & scientific | 2011 |
| Santarino (Market Square) Limited | Hospitality | 2021 |
| Sayer Scaffolding Ltd | Construction | 2023 |
| SBA Services Limited | Professional & scientific | 1994 |
| Scott & Skye Ltd | Wholesale & retail | 2024 |
| Simpson Plumbing & Heating Limited | Construction | 2012 |
| Somo Creation CIC | Arts & recreation | 2024 |
| South Manchester Resurfacing Ltd | Construction | 2022 |
| Stainmore Properties Limited | Real estate | 1997 |
| Stainmore Railway Company Limited | Wholesale & retail | 2000 |
| Stainmore Summit Limited | Agriculture & fishing | 2012 |
| Station Yard Developments Limited | Construction | 2016 |
| Stephen Barnes Accountancy Ltd | Professional & scientific | 2010 |
| Strombus Limited | Professional & scientific | 2008 |
| Style Shed Events Ltd | Administrative & support | 2022 |
| Syncronology Limited | Information & communication | 2005 |
| T R Handley Limited | Wholesale & retail | 1987 |
| Tarn Outdoor Centre Ltd | Hospitality | 2000 |
| THE Bank House Group Limited | Arts & recreation | 2016 |
| THE Biltong MAN Limited | Manufacturing | 2011 |
| THE Black Bull at Nateby Limited | Hospitality | 2022 |
| THE Branding Iron Ltd | Wholesale & retail | 2025 |
| THE Eco Merchandise Company Ltd | Professional & scientific | 2020 |
| THE Event Merchandise Company Ltd | Professional & scientific | 2020 |
| THE Facade Collective Architectural Solutions Ltd | Construction | 2025 |
| THE Green Tree Pharmacy Limited | Wholesale & retail | 2001 |
| THE Little Bike Company Limited | Wholesale & retail | 2012 |
| THE Pennine Hotel Limited | Hospitality | 2017 |
| THE Rigging Element Limited | Construction | 2024 |
| THE Student Merchandise Company Ltd | Professional & scientific | 2020 |
| THE Transformation Rooms Ltd | Arts & recreation | 2022 |
| THE Western Dales Community BUS Service Limited | Transport & logistics | 2012 |
| Thewheeliebinclub Ltd | Administrative & support | 2025 |
| Thomas Metcalfe Electrical Limited | Construction | 2020 |
| TIM Coburn Ltd | Professional & scientific | 2008 |
| Trytext Limited | Extraterritorial | 2014 |
| Tttaxis Ltd | Transport & logistics | 2026 |
| Tunstall Tractors Limited | Manufacturing | 1997 |
| Type & Test Limited | Information & communication | 2005 |
| Upper Eden Community Interest Company | Information & communication | 2011 |
| Upper Eden Home Care Services Limited | Health & social care | 2005 |
| Vale Farriery Limited | Other services | 2014 |
| Village Stores (Brough) Limited | Wholesale & retail | 2003 |
| Village Stores (Kirkby Stephen) Ltd | Wholesale & retail | 2023 |
| Walkers ARE Welcome CIC | Other services | 2015 |
| Walkingworld Limited | Information & communication | 2001 |
| Watershed Training Limited | Education | 1997 |
| Watt Translates Ltd | Professional & scientific | 2021 |
| WE ARE Team Limited | Arts & recreation | 2014 |
| Wearmouth Plant Hire Ltd | Construction | 2003 |
| Westmorland Scaffolding Ltd | Construction | 2023 |
| Westmorland Web Ltd | Information & communication | 2022 |
| Westwood Farm Management Limited | Real estate | 2006 |
| White Rhino Developments Limited | Real estate | 2024 |
| Wilkinson Property Services (Hartley) Ltd | Construction | 2011 |
| Winton Manor Court Limited | Real estate | 2003 |
| WM Building (Kirkby Stephen) Ltd | Construction | 2025 |
| Wpjl Innovations Ltd | Information & communication | 2025 |
| WPS Supplies Limited | Wholesale & retail | 2011 |
| Yorkshire Tours Limited | Extraterritorial | 2019 |